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Related papers: A Dataset for N-ary Relation Extraction of Drug Co…

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Combination drug therapies are treatment regimens that involve two or more drugs, administered more commonly for patients with cancer, HIV, malaria, or tuberculosis. Currently there are over 350K articles in PubMed that use the "combination…

Computation and Language · Computer Science 2023-03-30 Yuhang Jiang , Ramakanth Kavuluru

Medication Extraction and Mining play an important role in healthcare NLP research due to its practical applications in hospital settings, such as their mapping into standard clinical knowledge bases (SNOMED-CT, BNF, etc.). In this work, we…

Computation and Language · Computer Science 2024-12-31 Pablo Romero , Lifeng Han , Goran Nenadic

Most information extraction methods focus on binary relations expressed within single sentences. In high-value domains, however, $n$-ary relations are of great demand (e.g., drug-gene-mutation interactions in precision oncology). Such…

Computation and Language · Computer Science 2019-06-28 Robin Jia , Cliff Wong , Hoifung Poon

Biomedical Information Extraction is an exciting field at the crossroads of Natural Language Processing, Biology and Medicine. It encompasses a variety of different tasks that require application of state-of-the-art NLP techniques, such as…

Computation and Language · Computer Science 2017-05-17 Surag Nair

Relation extraction between drugs plays a crucial role in identifying drug drug interactions and predicting side effects. The advancement of machine learning methods in relation extraction, along with the development of large medical text…

Computation and Language · Computer Science 2025-10-28 Ali Fata , Hossein Rahmani , Parinaz Soltanzadeh , Amirhossein Derakhshan , Behrouz Minaei Bidgoli

Drug combination therapy is a well-established strategy for disease treatment with better effectiveness and less safety degradation. However, identifying novel drug combinations through wet-lab experiments is resource intensive due to the…

Machine Learning · Computer Science 2023-01-18 Zhihang Hu , Qinze Yu , Yucheng Guo , Taifeng Wang , Irwin King , Xin Gao , Le Song , Yu Li

Over the years several studies have demonstrated the ability to identify potential drug-drug interactions via data mining from the literature (MEDLINE), electronic health records, public databases (Drugbank), etc. While each one of these…

Computers and Society · Computer Science 2015-07-21 Juan M. Banda , Tobias Kuhn , Nigam H. Shah , Michel Dumontier

Mining relationships between treatment(s) and medical problem(s) is vital in the biomedical domain. This helps in various applications, such as decision support system, safety surveillance, and new treatment discovery. We propose a deep…

Machine Learning · Computer Science 2018-07-02 Veera Raghavendra Chikka , Kamalakar Karlapalem

How do we most effectively treat a disease or condition? Ideally, we could consult a database of evidence gleaned from clinical trials to answer such questions. Unfortunately, no such database exists; clinical trial results are instead…

Computation and Language · Computer Science 2020-05-15 Jay DeYoung , Eric Lehman , Ben Nye , Iain J. Marshall , Byron C. Wallace

Past work in relation extraction has focused on binary relations in single sentences. Recent NLP inroads in high-value domains have sparked interest in the more general setting of extracting n-ary relations that span multiple sentences. In…

Computation and Language · Computer Science 2017-08-15 Nanyun Peng , Hoifung Poon , Chris Quirk , Kristina Toutanova , Wen-tau Yih

One of the promising methods for the treatment of complex diseases such as cancer is combinational therapy. Due to the combinatorial complexity, machine learning models can be useful in this field, where significant improvements have…

Machine Learning · Computer Science 2020-01-08 Işıksu Ekşioğlu , Mehmet Tan

Relation extraction is a fundamental problem in natural language processing. Most existing models are defined for relation extraction in the general domain. However, their performance on specific domains (e.g., biomedicine) is yet unclear.…

Computation and Language · Computer Science 2021-12-14 Yongkang Li

The development of deep neural networks has improved representation learning in various domains, including textual, graph structural, and relational triple representations. This development opened the door to new relation extraction beyond…

Computation and Language · Computer Science 2022-12-22 Masaki Asada

Automated Drug Combination Extraction (DCE) from large-scale biomedical literature is crucial for advancing precision medicine and pharmacological research. However, existing relation extraction methods primarily focus on binary…

Computation and Language · Computer Science 2026-03-10 Zhijun Wang , Ling Luo , Dinghao Pan , Huan Zhuang , Lejing Yu , Yuanyuan Sun , Hongfei Lin

Drug-drug interaction (DDI) is a vital information when physicians and pharmacists intend to co-administer two or more drugs. Thus, several DDI databases are constructed to avoid mistakenly combined use. In recent years, automatically…

Computation and Language · Computer Science 2017-05-19 Zibo Yi , Shasha Li , Jie Yu , Qingbo Wu

More than 200 generic drugs approved by the U.S. Food and Drug Administration for non-cancer indications have shown promise for treating cancer. Due to their long history of safe patient use, low cost, and widespread availability,…

The surging amount of biomedical literature & digital clinical records presents a growing need for text mining techniques that can not only identify but also semantically relate entities in unstructured data. In this paper we propose a text…

Computation and Language · Computer Science 2021-12-28 Hasham Ul Haq , Veysel Kocaman , David Talby

Disease-symptom datasets are significant and in demand for medical research, disease diagnosis, clinical decision-making, and AI-driven health management applications. These datasets help identify symptom patterns associated with specific…

Computation and Language · Computer Science 2025-09-09 Abdullah Al Shafi , Rowzatul Zannat , Abdul Muntakim , Mahmudul Hasan

The effective extraction of ranked disease-symptom relationships is a critical component in various medical tasks, including computer-assisted medical diagnosis or the discovery of unexpected associations between diseases. While existing…

Information Retrieval · Computer Science 2020-01-16 Markus Zlabinger , Sebastian Hofstätter , Navid Rekabsaz , Allan Hanbury

Relation extraction is a critical task in the field of natural language processing with numerous real-world applications. Existing research primarily focuses on monolingual relation extraction or cross-lingual enhancement for relation…

Artificial Intelligence · Computer Science 2024-03-26 Lingxing Kong , Yougang Chu , Zheng Ma , Jianbing Zhang , Liang He , Jiajun Chen
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