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DNA sequencing is the physical/biochemical process of identifying the location of the four bases (Adenine, Guanine, Cytosine, Thymine) in a DNA strand. As semiconductor technology revolutionized computing, modern DNA sequencing technology…

Distributed, Parallel, and Cluster Computing · Computer Science 2020-05-06 S. Karen Khatamifard , Zamshed Chowdhury , Nakul Pande , Meisam Razaviyayn , Chris Kim , Ulya R. Karpuzcu

Motivation: Deep learning architectures have recently demonstrated their power in predicting DNA- and RNA-binding specificities. Existing methods fall into three classes: Some are based on Convolutional Neural Networks (CNNs), others use…

Machine Learning · Computer Science 2019-01-31 Ameni Trabelsi , Mohamed Chaabane , Asa Ben Hur

Neural networks are an increasingly attractive algorithm for natural language processing and pattern recognition. Deep networks with >50M parameters are made possible by modern GPU clusters operating at <50 pJ per op and more recently,…

Advancement in Processor technology has made it easy to handle data-intensive workloads, but limiting main memory advances has created performance bottlenecks. In DRAM, there have been improvements in DRAM access latency as well as…

Hardware Architecture · Computer Science 2021-05-24 Saurabh Jaiswal , Shailendra Kumar Gupta , Soumya Soubhagya Dandapat

Content addressable memory is popular in intelligent computing systems as it allows parallel content-searching in memory. Emerging CAMs show a promising increase in bitcell density and a decrease in power consumption than pure CMOS…

Systems and Control · Electrical Eng. & Systems 2024-09-17 Yihan Pan , Adrian Wheeldon , Mohammed Mughal , Shady Agwa , Themis Prodromakis , Alexantrou Serb

AI chips commonly employ SRAM memory as buffers for their reliability and speed, which contribute to high performance. However, SRAM is expensive and demands significant area and energy consumption. Previous studies have explored replacing…

Hardware Architecture · Computer Science 2023-12-07 Duy-Thanh Nguyen , Abhiroop Bhattacharjee , Abhishek Moitra , Priyadarshini Panda

Neural networks (NNs) are growing in importance and complexity. A neural network's performance (and energy efficiency) can be bound either by computation or memory resources. The processing-in-memory (PIM) paradigm, where computation is…

Hardware Architecture · Computer Science 2023-03-28 Geraldo F. Oliveira , Juan Gómez-Luna , Saugata Ghose , Amirali Boroumand , Onur Mutlu

Arising disruptive memory technologies continuously make their way into the memory hierarchy at various levels. Racetrack memory is one promising candidate for future memory due to the overall low energy consumption, access latency and high…

Hardware Architecture · Computer Science 2025-03-03 Christian Hakert , Shuo-Han Chen , Kay Heider , Roland Kühn , Yun-Chih Chen , Jens Teubner , Jian-Jia Chen

With the emergence of Non-Volatile Memories (NVMs) and their shortcomings such as limited endurance and high power consumption in write requests, several studies have suggested hybrid memory architecture employing both Dynamic Random Access…

Operating Systems · Computer Science 2018-05-08 Reza Salkhordeh , Hossein Asadi

Gene prioritization (identifying genes potentially associated with a biological process) is increasingly tackled with Artificial Intelligence. However, existing methods struggle with the high dimensionality and incomplete labelling of…

Processing-in-memory (PIM), as a novel computing paradigm, provides significant performance benefits from the aspect of effective data movement reduction. SRAM-based PIM has been demonstrated as one of the most promising candidates due to…

Hardware Architecture · Computer Science 2023-11-01 Cenlin Duan , Jianlei Yang , Xiaolin He , Yingjie Qi , Yikun Wang , Yiou Wang , Ziyan He , Bonan Yan , Xueyan Wang , Xiaotao Jia , Weitao Pan , Weisheng Zhao

Persistent Memory (PM) technologies enable program recovery to a consistent state in a case of failure. To ensure this crash-consistent behavior, programs need to enforce persist ordering by employing mechanisms, such as logging and…

Computational Engineering, Finance, and Science · Computer Science 2023-04-03 Yasas Seneviratne , Korakit Seemakhupt , Sihang Liu , Samira Khan

Convolutional neural networks (CNN) have become a ubiquitous algorithm with growing applications in mobile and edge settings. We describe a compute-in-memory (CIM) technique called FPIRM using Racetrack Memory (RM) to accelerate CNNs for…

Emerging Technologies · Computer Science 2022-08-02 Sébastien Ollivier , Xinyi Zhang , Yue Tang , Chayanika Choudhuri , Jingtong Hu , Alex K. Jones

DNA sequence classification is a fundamental task in computational biology with vast implications for applications such as disease prevention and drug design. Therefore, fast high-quality sequence classifiers are significantly important.…

Machine Learning · Computer Science 2023-11-07 Marcel Khalifa , Barak Hoffer , Orian Leitersdorf , Robert Hanhan , Ben Perach , Leonid Yavits , Shahar Kvatinsky

Deep neural networks (DNNs) have revolutionized the field of artificial intelligence and have achieved unprecedented success in cognitive tasks such as image and speech recognition. Training of large DNNs, however, is computationally…

On-device learning allows AI models to adapt to user data, thereby enhancing service quality on edge platforms. However, training AI on resource-limited devices poses significant challenges due to the demanding computing workload and the…

Hardware Architecture · Computer Science 2023-12-27 Sai Qian Zhang , Thierry Tambe , Nestor Cuevas , Gu-Yeon Wei , David Brooks

Near-Data Processing refers to an architectural hardware and software paradigm, based on the co-location of storage and compute units. Ideally, it will allow to execute application-defined data- or compute-intensive operations in-situ, i.e.…

Databases · Computer Science 2019-05-14 Tobias Vincon , Andreas Koch , Ilia Petrov

With the imminent slowing down of DRAM scaling, Phase Change Memory (PCM) is emerging as a lead alternative for main memory technology. While PCM achieves low energy due to various technology-specific advantages, PCM is significantly slower…

Hardware Architecture · Computer Science 2015-04-17 Hamza Bin Sohail , Balajee Vamanan , T. N. Vijaykumar

DNA-based storage is an emerging technology that enables digital information to be archived in DNA molecules. This method enjoys major advantages over magnetic and optical storage solutions such as exceptional information density, enhanced…

Information Theory · Computer Science 2024-03-13 Daniella Bar-Lev , Itai Orr , Omer Sabary , Tuvi Etzion , Eitan Yaakobi

Large Language Models (LLMs) are increasingly deployed on edge devices with Neural Processing Units (NPUs), yet the decode phase remains memory-intensive, limiting performance. Processing-in-Memory (PIM) offers a promising solution, but…

Distributed, Parallel, and Cluster Computing · Computer Science 2026-05-18 Hai Huang