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Mitosis nuclei count is one of the important indicators for the pathological diagnosis of breast cancer. The manual annotation needs experienced pathologists, which is very time-consuming and inefficient. With the development of deep…

Computer Vision and Pattern Recognition · Computer Science 2022-12-29 Huadeng Wang , Zhipeng Liu , Rushi Lan , Zhenbing Liu , Xiaonan Luo , Xipeng Pan , Bingbing Li

Motivation: Multi-omics integration can improve cancer subtyping, but modality informativeness and noise vary across cancer types and patients. Existing graph-based methods optimize modality weights jointly with the classification objective…

Machine Learning · Computer Science 2026-04-28 Boyang Fan , Hengchuang Yin , Siyu Yi , Yifan Wang , Zhicheng Li , Leijiyu Zhou , Jiancheng Lv , Wei Ju

Breast cancer is the most common cancer and is the leading cause of cancer death among women worldwide. Detection of breast cancer, while it is still small and confined to the breast, provides the best chance of effective treatment.…

Background: Breast density, as derived from mammographic images and defined by the American College of Radiology's Breast Imaging Reporting and Data System (BI-RADS), is one of the strongest risk factors for breast cancer. Breast ultrasound…

Mammographic density is a dynamic risk factor for breast cancer and affects the sensitivity of mammography-based screening. While automated machine and deep learning-based methods provide more consistent and precise measurements compared to…

Current analysis of tumor proliferation, the most salient prognostic biomarker for invasive breast cancer, is limited to subjective mitosis counting by pathologists in localized regions of tissue images. This study presents the first…

Computer Vision and Pattern Recognition · Computer Science 2016-10-12 Manan Shah , Christopher Rubadue , David Suster , Dayong Wang

We propose a new method for breast cancer screening from DCE-MRI based on a post-hoc approach that is trained using weakly annotated data (i.e., labels are available only at the image level without any lesion delineation). Our proposed…

Computer Vision and Pattern Recognition · Computer Science 2019-02-05 Gabriel Maicas , Andrew P. Bradley , Jacinto C. Nascimento , Ian Reid , Gustavo Carneiro

Segmenting a MRI images into homogeneous texture regions representing disparate tissue types is often a useful preprocessing step in the computer-assisted detection of breast cancer. That is why we proposed new algorithm to detect cancer in…

Computer Vision and Pattern Recognition · Computer Science 2010-01-26 H. B. Kekre , Tanuja K. Sarode , Saylee M. Gharge

Breast cancer has become one of the most prevalent cancers by which people all over the world are affected and is posed serious threats to human beings, in a particular woman. In order to provide effective treatment or prevention of this…

Image and Video Processing · Electrical Eng. & Systems 2021-07-15 Pouya Hallaj Zavareh , Atefeh Safayari , Hamidreza Bolhasani

Deep neural networks (DNNs) show promise in breast cancer screening, but their robustness to input perturbations must be better understood before they can be clinically implemented. There exists extensive literature on this subject in the…

Although digital breast tomosynthesis (DBT) improves diagnostic performance over full-field digital mammography (FFDM), false-positive recalls remain a concern in breast cancer screening. We developed a multi-modal artificial intelligence…

Image and Video Processing · Electrical Eng. & Systems 2025-04-14 Jungkyu Park , Jan Witowski , Yanqi Xu , Hari Trivedi , Judy Gichoya , Beatrice Brown-Mulry , Malte Westerhoff , Linda Moy , Laura Heacock , Alana Lewin , Krzysztof J. Geras

Trustworthy classifiers are essential to the adoption of machine learning predictions in many real-world settings. The predicted probability of possible outcomes can inform high-stakes decision making, particularly when assessing the…

Machine Learning · Computer Science 2023-02-22 Kiri L. Wagstaff , Thomas G. Dietterich

Breast Cancer is a major cause of death worldwide among women. Hematoxylin and Eosin (H&E) stained breast tissue samples from biopsies are observed under microscopes for the primary diagnosis of breast cancer. In this paper, we propose a…

Computer Vision and Pattern Recognition · Computer Science 2018-07-26 Aditya Golatkar , Deepak Anand , Amit Sethi

Dynamic Contrast Enhanced-Magnetic Resonance Imaging (DCE-MRI) is widely used to complement ultrasound examinations and x-ray mammography during the early detection and diagnosis of breast cancer. However, images generated by various MRI…

Image and Video Processing · Electrical Eng. & Systems 2021-06-18 Gourav Modanwal , Adithya Vellal , Maciej A. Mazurowski

Predicting breast cancer recurrence risk is a critical clinical challenge. This study investigates the potential of computational pathology to stratify patients using deep learning on routine Hematoxylin and Eosin (H&E) stained whole-slide…

Computer Vision and Pattern Recognition · Computer Science 2025-12-23 Jinqiu Chen , Huyan Xu

Mammography is the most widely used gold standard for screening breast cancer, where, mass detection is considered as the prominent step. Detecting mass in the breast is, however, an arduous problem as they usually have large variations…

Computer Vision and Pattern Recognition · Computer Science 2019-07-11 Md. Kamrul Hasan , Tajwar Abrar Aleef

As machine learning (ML) continue to be integrated into healthcare systems that affect clinical decision making, new strategies will need to be incorporated in order to effectively detect and evaluate subgroup disparities to ensure…

Machine Learning · Computer Science 2021-07-19 Charles Lu , Andreanne Lemay , Katharina Hoebel , Jayashree Kalpathy-Cramer

A computer-aided detection (CADe) system for the identification of microcalcification clusters in digital mammograms has been developed. It is mainly based on the application of wavelet transforms for image filtering and neural networks for…

Medical Physics · Physics 2009-04-15 P. Delogu , M. E. Fantacci , A. Retico , A. Stefanini , A. Tata

Objectives: To assess evaluative methodologies for comparative measurements of test sensitivity in clinical mammographic screening trials of computer-aided detection (CAD) technologies. Materials and Methods: This meta-analysis was…

Medical Physics · Physics 2013-02-07 Jacob Levman

Federated learning enables collaborative training of deep learning models across institutions without sharing sensitive patient data. However, its performance is often limited by small datasets and non-independent, identically distributed…

Image and Video Processing · Electrical Eng. & Systems 2026-04-17 Hongyi Pan , Ziliang Hong , Gorkem Durak , Ziyue Xu , Ulas Bagci