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Fast spin-echo (FSE) pulse sequences for Magnetic Resonance Imaging (MRI) offer important imaging contrast in clinically feasible scan times. T2-shuffling is widely used to resolve temporal signal dynamics in FSE acquisitions by exploiting…

Image reconstruction in low-count PET is particularly challenging because gammas from natural radioactivity in Lu-based crystals cause high random fractions that lower the measurement signal-to-noise-ratio (SNR). In model-based image…

Most existing methods usually formulate the non-blind deconvolution problem into a maximum-a-posteriori framework and address it by manually designing kinds of regularization terms and data terms of the latent clear images. However,…

Despite perfectly interpolating the training data, deep neural networks (DNNs) can often generalize fairly well, in part due to the "implicit regularization" induced by the learning algorithm. Nonetheless, various forms of regularization,…

While much work has been devoted to understanding the implicit (and explicit) regularization of deep nonlinear networks in the supervised setting, this paper focuses on unsupervised learning, i.e., autoencoders are trained with the…

We present deformable unsupervised medical image registration using a randomly-initialized deep convolutional neural network (CNN) as regularization prior. Conventional registration methods predict a transformation by minimizing…

Deep neural network based methods are the state of the art in various image restoration problems. Standard supervised learning frameworks require a set of noisy measurement and clean image pairs for which a distance between the output of…

Natural images tend to mostly consist of smooth regions with individual pixels having highly correlated spectra. This information can be exploited to recover hyperspectral images of natural scenes from their incomplete and noisy…

Coded aperture is a promising approach for capturing the 4-D light field (LF), in which the 4-D data are compressively modulated into 2-D coded measurements that are further decoded by reconstruction algorithms. The bottleneck lies in the…

Reconstructing an image from its Radon transform is a fundamental computed tomography (CT) task arising in applications such as X-ray scans. In many practical scenarios, a full 180-degree scan is not feasible, or there is a desire to reduce…

Regularization for denoising in magnetic resonance imaging (MRI) is typically achieved using convex regularization functions. Recently, deep learning techniques have been shown to provide superior denoising performance. However, this comes…

Low-Dose computer tomography (LDCT) is an ideal alternative to reduce radiation risk in clinical applications. Although supervised-deep-learning-based reconstruction methods have demonstrated superior performance compared to conventional…

Deep learning (DL) has recently emerged to address the heavy storage and computation requirements of the baseline dictionary-matching (DM) for Magnetic Resonance Fingerprinting (MRF) reconstruction. Fed with non-iterated back-projected…

Objective: Acquiring fully sampled training data is challenging for many MRI applications. We present a self-supervised image reconstruction method, termed ReSiDe, capable of recovering images solely from undersampled data. Materials and…

We construct custom regularization functions for use in supervised training of deep neural networks. Our technique is applicable when the ground-truth labels themselves exhibit internal structure; we derive a regularizer by learning an…

The unrolling method has been investigated for learning variational models in X-ray computed tomography. However, it has been observed that directly unrolling the regularization model through gradient descent does not produce satisfactory…

Deep learning (DL) has shown promise for faster, high quality accelerated MRI reconstruction. However, supervised DL methods depend on extensive amounts of fully-sampled (labeled) data and are sensitive to out-of-distribution (OOD) shifts,…

In this work we propose a deep learning network for deformable image registration (DIRNet). The DIRNet consists of a convolutional neural network (ConvNet) regressor, a spatial transformer, and a resampler. The ConvNet analyzes a pair of…

Purpose: To develop and assess a deep learning (DL) pipeline to learn dynamic MR image reconstruction from publicly available natural videos (Inter4K). Materials and Methods: Learning was performed for a range of DL architectures (VarNet,…

Magnetic Resonance Imaging (MRI) is a widely used imaging technique, however it has the limitation of long scanning time. Though previous model-based and learning-based MRI reconstruction methods have shown promising performance, most of…