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Sequence alignment algorithms are a basic and critical component of many bioinformatics fields. With rapid development of sequencing technology, the fast growing reference database volumes and longer length of query sequence become new…

Distributed, Parallel, and Cluster Computing · Computer Science 2017-01-09 Bo Xu , Changlong Li , Hang Zhuang , Jiali Wang , Qingfeng Wang , Jinhong Zhou , Xuehai Zhou

The performance gains obtained by large language models (LLMs) are closely linked to their substantial computational and memory requirements. Quantized LLMs offer significant advantages with extremely quantized models, motivating the…

Hardware Architecture · Computer Science 2026-04-07 Ahmed J. Abdelmaksoud , Cristian Sestito , Shiwei Wang , Themis Prodromakis

Recent hardware acceleration advances have enabled powerful specialized accelerators for finite element computations, spiking neural network inference, and sparse tensor operations. However, existing approaches face fundamental limitations:…

Hardware Architecture · Computer Science 2026-01-09 Chuanzhen Wang , Leo Zhang , Eric Liu

Neural networks (NNs) are growing in importance and complexity. A neural network's performance (and energy efficiency) can be bound either by computation or memory resources. The processing-in-memory (PIM) paradigm, where computation is…

Hardware Architecture · Computer Science 2023-03-28 Geraldo F. Oliveira , Juan Gómez-Luna , Saugata Ghose , Amirali Boroumand , Onur Mutlu

Multidimensional Retiming is one of the most important optimization techniques to improve timing parameters of nested loops. It consists in exploring the iterative and recursive structures of loops to redistribute computation nodes on cycle…

Programming Languages · Computer Science 2012-05-22 Yaroub Elloumi , Mohamed Akil , Mohamed Hedi Bedoui

Developing a structured method for analyzing various aspects of a system requires a novel methodology. This study is aimed at developing such as methodology through combining two major matrix methods, namely, Design Structure Matrix (DSM)…

Systems and Control · Electrical Eng. & Systems 2019-07-02 Hossein Sabzian , Seyyed Mostafa Seyyed Hashemi , Ehsan Kamrani

Simple graph algorithms such as PageRank have been the target of numerous hardware accelerators. Yet, there also exist much more complex graph mining algorithms for problems such as clustering or maximal clique listing. These algorithms are…

Atomistic simulation drives scientific advances in modern material science and accounts for a significant proportion of wall time on High Performance Computing facilities. It is important that algorithms are efficient and implementations…

Distributed, Parallel, and Cluster Computing · Computer Science 2020-07-21 William Robert Saunders , James Grant , Eike Hermann Müller

Generalized sparse matrix-matrix multiplication is a key primitive for many high performance graph algorithms as well as some linear solvers such as multigrid. We present the first parallel algorithms that achieve increasing speedups for an…

Distributed, Parallel, and Cluster Computing · Computer Science 2016-08-09 Aydın Buluç , John R. Gilbert

Graphics Processing Units (GPUs) have become the standard in accelerating scientific applications on heterogeneous systems. However, as GPUs are getting faster, one potential performance bottleneck with GPU-accelerated applications is the…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-05-01 Jonah Ekelund , Stefano Markidis , Ivy Peng

Continual learning on edge platforms remains challenging because recurrent networks depend on energy-intensive training procedures and frequent data movement that are impractical for embedded deployments. This work introduces M2RU, a…

Machine Learning · Computer Science 2025-12-29 Abdullah M. Zyarah , Dhireesha Kudithipudi

Modern central processing units (CPUs) feature single-instruction, multiple-data pipelines to accelerate compute-intensive floating-point and fixed-point workloads. Traditionally, these pipelines and corresponding instruction set…

Distributed, Parallel, and Cluster Computing · Computer Science 2024-09-30 Stefan Remke , Alexander Breuer

Our goal in this dissertation is to provide tools, programming models, and system support for PIM architectures (with a focus on DRAM-based solutions), to ease the adoption of PIM in current and future systems. To this end, we make at least…

Hardware Architecture · Computer Science 2025-08-28 Geraldo F. Oliveira

Among the algorithms that are likely to play a major role in future exascale computing, the fast multipole method (FMM) appears as a rising star. Our previous recent work showed scaling of an FMM on GPU clusters, with problem sizes in the…

Numerical Analysis · Computer Science 2012-10-30 Rio Yokota , Lorena Barba

The Nvidia GPU architecture has introduced new computing elements such as the \textit{tensor cores}, which are special processing units dedicated to perform fast matrix-multiply-accumulate (MMA) operations and accelerate \textit{Deep…

Distributed, Parallel, and Cluster Computing · Computer Science 2019-03-12 Roberto Carrasco , Raimundo Vega , Cristóbal A. Navarro

We present GSPMD, an automatic, compiler-based parallelization system for common machine learning computations. It allows users to write programs in the same way as for a single device, then give hints through a few annotations on how to…

Many of today's deep neural network accelerators, e.g., Google's TPU and NVIDIA's tensor core, are built around accelerating the general matrix multiplication (i.e., GEMM). However, supporting convolution on GEMM-based accelerators is not…

Distributed, Parallel, and Cluster Computing · Computer Science 2021-10-11 Yangjie Zhou , Mengtian Yang , Cong Guo , Jingwen Leng , Yun Liang , Quan Chen , Minyi Guo , Yuhao Zhu

Modern computing workloads commonly involve matrix-matrix multiplication (mmul) as a core computing pattern. Coarse-Grained Reconfigurable Arrays (CGRAs) can flexibly and efficiently support it, since they combine operation-level…

Hardware Architecture · Computer Science 2026-04-29 Yuxuan Wang , María José Belda , Fernando Castro , Katzalin Olcoz , David Atienza , Giovanni Ansaloni

The accurate assembly of the system matrix is an important step in any code that solves partial differential equations on a mesh. We either explicitly set up a matrix, or we work in a matrix-free environment where we have to be able to…

Mathematical Software · Computer Science 2020-06-19 Charles D. Murray , Tobias Weinzierl

The currently dominant AI/ML workloads, such as Large Language Models (LLMs), rely on the efficient execution of General Matrix-Matrix Multiplication (GEMM) operations. Thus, most systems are equipped with dedicated matrix hardware…

Hardware Architecture · Computer Science 2026-04-01 Luigi Altamura , Alessio Cicero , Mateo Vázquez Maceiras , Mohammad Ali Maleki , Pedro Trancoso