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Despite the growing availability of Electronic Health Record (EHR) data, researchers often face substantial barriers in effectively using these data for translational research due to their complexity, heterogeneity, and lack of standardized…

The Electronic Health Record (EHR) is an essential part of the modern medical system and impacts healthcare delivery, operations, and research. Unstructured text is attracting much attention despite structured information in the EHRs and…

Computation and Language · Computer Science 2023-06-29 Irene Li , Keen You , Yujie Qiao , Lucas Huang , Chia-Chun Hsieh , Benjamin Rosand , Jeremy Goldwasser , Dragomir Radev

The demand for emergency department (ED) services is increasing across the globe, particularly during the current COVID-19 pandemic. Clinical triage and risk assessment have become increasingly challenging due to the shortage of medical…

The adoption of digital systems in healthcare has resulted in the accumulation of vast electronic health records (EHRs), offering valuable data for machine learning methods to predict patient health outcomes. However, single-visit records…

Machine Learning · Computer Science 2024-11-19 Eric Yang , Pengfei Hu , Xiaoxue Han , Yue Ning

We conduct a scoping review of existing approaches for synthetic EHR data generation, and benchmark major methods with proposed open-source software to offer recommendations for practitioners. We search three academic databases for our…

Machine Learning · Computer Science 2025-06-05 Xingran Chen , Zhenke Wu , Xu Shi , Hyunghoon Cho , Bhramar Mukherjee

The growing demand for machine learning in healthcare requires processing increasingly large electronic health record (EHR) datasets, but existing pipelines are not computationally efficient or scalable. In this paper, we introduce…

Machine Learning · Computer Science 2024-11-18 Ethan Steinberg , Michael Wornow , Suhana Bedi , Jason Alan Fries , Matthew B. A. McDermott , Nigam H. Shah

Among various aspects of ensuring the responsible design of AI tools for healthcare applications, addressing fairness concerns has been a key focus area. Specifically, given the wide spread of electronic health record (EHR) data and their…

Machine Learning · Computer Science 2025-06-30 Mirza Farhan Bin Tarek , Raphael Poulain , Rahmatollah Beheshti

The recent release of large-scale healthcare datasets has greatly propelled the research of data-driven deep learning models for healthcare applications. However, due to the nature of such deep black-boxed models, concerns about…

Machine Learning · Computer Science 2021-02-16 Chuizheng Meng , Loc Trinh , Nan Xu , Yan Liu

The pivotal shift from traditional paper-based records to sophisticated Electronic Health Records (EHR), enabled systematic collection and analysis of patient data through descriptive statistics, providing insight into patterns and trends…

Artificial Intelligence · Computer Science 2025-02-18 Muhammet Alkan , Hester Huijsdens , Yola Jones , Fani Deligianni

Sepsis is a leading cause of mortality in intensive care units (ICUs), yet existing research often relies on outdated datasets, non-reproducible preprocessing pipelines, and limited coverage of clinical interventions. We introduce…

Machine Learning · Computer Science 2025-10-29 Yong Huang , Zhongqi Yang , Amir Rahmani

Predicting disease trajectories from electronic health records (EHRs) is a complex task due to major challenges such as data non-stationarity, high granularity of medical codes, and integration of multimodal data. EHRs contain both…

Machine Learning · Computer Science 2025-02-26 Sifal Klioui , Sana Sellami , Youssef Trardi

Electronic Health Records (EHRs) contain rich yet complex information, and their automated analysis is critical for clinical decision-making. Despite recent advances of large language models (LLMs) in clinical workflows, their ability to…

Computation and Language · Computer Science 2025-11-26 Yusheng Liao , Chaoyi Wu , Junwei Liu , Shuyang Jiang , Pengcheng Qiu , Haowen Wang , Yun Yue , Shuai Zhen , Jian Wang , Qianrui Fan , Jinjie Gu , Ya Zhang , Yanfeng Wang , Yu Wang , Weidi Xie

There are a few challenges related to the task of biomedical named entity recognition, which are: the existing methods consider a fewer number of biomedical entities (e.g., disease, symptom, proteins, genes); and these methods do not…

Computation and Language · Computer Science 2022-07-05 Shaina Raza , Brian Schwartz

Electronic health records (EHRs) contain a vast amount of high-dimensional multi-modal data that can accurately represent a patient's medical history. Unfortunately, most of this data is either unstructured or semi-structured, rendering it…

Computation and Language · Computer Science 2023-12-06 Ashwyn Sharma , David I. Feldman , Aneesh Jain

Phenotyping consists in applying algorithms to identify individuals associated with a specific, potentially complex, trait or condition, typically out of a collection of Electronic Health Records (EHRs). Because a lot of the clinical…

The inherent complexity of structured longitudinal Electronic Health Records (EHR) data poses a significant challenge when integrated with Large Language Models (LLMs), which are traditionally tailored for natural language processing.…

Computation and Language · Computer Science 2024-02-13 Yinghao Zhu , Zixiang Wang , Junyi Gao , Yuning Tong , Jingkun An , Weibin Liao , Ewen M. Harrison , Liantao Ma , Chengwei Pan

Access to electronic health records (EHRs) for digital health research is often limited by privacy regulations and institutional barriers. Synthetic EHRs have been proposed as a way to enable safe and sovereign data sharing; however,…

Machine Learning · Computer Science 2026-03-10 Guanglin Zhou , Armin Catic , Motahare Shabestari , Matthew Young , Chaiquan Li , Katrina Poppe , Sebastiano Barbieri

Reliable prediction of pediatric obesity can offer a valuable resource to providers, helping them engage in timely preventive interventions before the disease is established. Many efforts have been made to develop ML-based predictive models…

The availability of both structured and unstructured databases, such as electronic health data, social media data, patent data, and surveys that are often updated in real time, among others, has grown rapidly over the past decade. With this…

Databases · Computer Science 2023-07-26 Rebecca C. Steorts

In recent years, human in silico trials have gained significant traction as a powerful approach to evaluate the effects of drugs, clinical interventions, and medical devices. In silico trials not only minimise patient risks but also reduce…

Computational Engineering, Finance, and Science · Computer Science 2025-03-06 Ruben Doste , Julia Camps , Zhinuo Jenny Wang , Lucas Arantes Berg , Maxx Holmes , Hannah Smith , Marcel Beetz , Lei Li , Abhirup Banerjee , Vicente Grau , Blanca Rodriguez