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BioNetGen is an open-source software package for rule-based modeling of complex biochemical systems. Version 2.2 of the software introduces numerous new features for both model specification and simulation. Here, we report on these…

There is a need for open-source libraries in emission tomography that (i) use modern and popular backend code to encourage community contributions and (ii) offer support for the multitude of reconstruction techniques available in recent…

A plethora of protein language models have been released in recent years. Yet comparatively little work has addressed how to best sample from them to optimize desired biological properties. We fill this gap by proposing a flexible,…

Machine Learning · Computer Science 2026-05-08 Calvin McCarter , Nick Bhattacharya , Sebastian W. Ober , Hunter Elliott

As data science and machine learning methods are taking on an increasingly important role in the materials research community, there is a need for the development of machine learning software tools that are easy to use (even for nonexperts…

Computational Physics · Physics 2020-06-26 Ryan Jacobs , Tam Mayeshiba , Ben Afflerbach , Luke Miles , Max Williams , Matthew Turner , Raphael Finkel , Dane Morgan

This article introduces a metamodel for the Business Model Canvas (BMC) using the Unified Modelling Language (UML), together with a dedicated Domain-Specific Modelling Language (DSML) tool. Although the BMC is widely adopted by both…

Software Engineering · Computer Science 2026-02-16 Nordine Benkeltoum

We propose SPHINX-X, an extensive Multimodality Large Language Model (MLLM) series developed upon SPHINX. To improve the architecture and training efficiency, we modify the SPHINX framework by removing redundant visual encoders, bypassing…

Computer Vision and Pattern Recognition · Computer Science 2025-03-24 Dongyang Liu , Renrui Zhang , Longtian Qiu , Siyuan Huang , Weifeng Lin , Shitian Zhao , Shijie Geng , Ziyi Lin , Peng Jin , Kaipeng Zhang , Wenqi Shao , Chao Xu , Conghui He , Junjun He , Hao Shao , Pan Lu , Hongsheng Li , Yu Qiao , Peng Gao

PyMOLfold is a flexible and open-source plugin designed to seamlessly integrate AI-based protein structure prediction and visualization within the widely used PyMOL molecular graphics system. By leveraging state-of-the-art protein folding…

Biomolecules · Quantitative Biology 2025-02-04 Colby T. Ford , Samee Ullah , Dinler Amaral Antunes , Tarsis Gesteira Ferreira

This paper introduces diffusion protein language model (DPLM), a versatile protein language model that demonstrates strong generative and predictive capabilities for protein sequences. We first pre-train scalable DPLMs from…

Machine Learning · Computer Science 2024-10-17 Xinyou Wang , Zaixiang Zheng , Fei Ye , Dongyu Xue , Shujian Huang , Quanquan Gu

There has been an explosion in interest in machine learning (ML) in recent years due to its applications to science and engineering. However, as ML techniques have advanced, tools for explaining and visualizing novel ML algorithms have…

Machine Learning · Computer Science 2023-11-16 Alec Helbling , Duen Horng Chau

BioScape is a concurrent language motivated by the biological landscapes found at the interface of biology and biomaterials. It has been motivated by the need to model antibacterial surfaces, biofilm formation, and the effect of DNAse in…

Logic in Computer Science · Computer Science 2012-11-21 Adriana Compagnoni , Mariangiola Dezani-Ciancaglini , Paola Giannini , Karin Sauer , Vishakha Sharma , Angelo Troina

Although Raman spectroscopy is widely used for the investigation of biomedical samples and has a high potential for use in clinical applications, it is not common in clinical routines. One of the factors that obstruct the integration of…

Data Analysis, Statistics and Probability · Physics 2022-01-20 Darina Storozhuk , Oleg Ryabchykov , Juergen Popp , Thomas Bocklitz

Scikit-learn is a Python module integrating a wide range of state-of-the-art machine learning algorithms for medium-scale supervised and unsupervised problems. This package focuses on bringing machine learning to non-specialists using a…

In Business Process Management (BPM), effectively comprehending process models is crucial yet poses significant challenges, particularly as organizations scale and processes become more complex. This paper introduces a novel framework…

Extracting structured information from unstructured text is crucial for modeling real-world processes, but traditional schema mining relies on semi-structured data, limiting scalability. This paper introduces schema-miner, a novel tool that…

Nowadays the analysis of dynamics of and on networks represents a hot topic in the Social Network Analysis playground. To support students, teachers, developers and researchers in this work we introduce a novel framework, namely NDlib, an…

Social and Information Networks · Computer Science 2018-01-19 Giulio Rossetti , Letizia Milli , Salvatore Rinzivillo , Alina Sirbu , Fosca Giannotti , Dino Pedreschi

A 3D scene graph represents a compact scene model by capturing both the objects present and the semantic relationships between them, making it a promising structure for robotic applications. To effectively interact with users, an embodied…

Computer Vision and Pattern Recognition · Computer Science 2025-08-07 Tatiana Zemskova , Dmitry Yudin

Large Language Models (LLMs) are increasingly applied in the fields of mechanical engineering and materials science. As models that establish connections through the interface of language, LLMs can be applied for step-wise reasoning through…

Applied Physics · Physics 2025-07-22 Adrian Ehrenhofer , Thomas Wallmersperger , Gianaurelio Cuniberti

$\textit{Pymc-learn}$ is a Python package providing a variety of state-of-the-art probabilistic models for supervised and unsupervised machine learning. It is inspired by $\textit{scikit-learn}$ and focuses on bringing probabilistic machine…

Machine Learning · Statistics 2018-11-05 Daniel Emaasit

Any cutting-edge scientific research project requires a myriad of computational tools for data generation, management, analysis and visualization. Python is a flexible and extensible scientific programming platform that offered the perfect…

Quantitative Methods · Quantitative Biology 2008-03-14 Julius B. Lucks

This paper presents evomap, a Python package for dynamic mapping. Mapping methods are widely used across disciplines to visualize relationships among objects as spatial representations, or maps. However, most existing statistical software…

Mathematical Software · Computer Science 2025-11-07 Maximilian Matthe
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