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The novel coronavirus (SARS-CoV-2) has led to a pandemic. The current testing regime based on Reverse Transcription-Polymerase Chain Reaction for SARS-CoV-2 has been unable to keep up with testing demands, and also suffers from a relatively…

Rapid testing is essential to fighting pandemics such as COVID-19, the disease caused by the SARS-CoV-2 virus. Exhaled human breath contains multiple volatile molecules providing powerful potential for non-invasive diagnosis of diverse…

Rapid, sensitive detection of biomolecules is important for improved testing methods for viruses as well as biomarkers and environmental hormones. For example, testing for SARS-CoV-2 is essential in the fight against the COVID-19 pandemic.…

Formulating accurate and robust classification strategies is a key challenge of developing diagnostic and antibody tests. Methods that do not explicitly account for disease prevalence and uncertainty therein can lead to significant…

Methodology · Statistics 2022-02-01 Paul N. Patrone , Anthony J. Kearsley

To support the ongoing management of viral respiratory diseases, many countries are moving towards an integrated model of surveillance for SARS-CoV-2, influenza, and other respiratory pathogens. While many surveillance approaches catalysed…

After emerging in China in late 2019, the novel Severe acute respiratory syndrome-like coronavirus 2 (SARS-CoV-2) spread worldwide and as of early 2021, continues to significantly impact most countries. Only a small number of coronaviruses…

Future SARS-CoV-2 virus outbreak COVID-XX might possibly occur during the next years. However the pathology in humans is so recent that many clinical aspects, like early detection of complications, side effects after recovery or early…

Image and Video Processing · Electrical Eng. & Systems 2020-05-29 D. Gil , K. Díaz-Chito , C. Sánchez , A. Hernández-Sabaté

Large-scale testing is considered key to assess the state of the current COVID-19 pandemic. Yet, the link between the reported case numbers and the true state of the pandemic remains elusive. We develop mathematical models based on…

Applications · Statistics 2021-02-04 Michel Besserve , Simon Buchholz , Bernhard Schölkopf

This paper presents a critical analysis of the literature and perspective research ideas for modeling the epidemics caused by the SARS-CoV-2 virus. It goes beyond deterministic population dynamics to consider several key complexity features…

Populations and Evolution · Quantitative Biology 2025-01-24 Giulia Bertaglia , Andrea Bondesan , Diletta Burini , Raluca Eftimie , Lorenzo Pareschi , Giuseppe Toscani

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has a variable clinical presentation that ranges from asymptomatic, to severe disease with cytokine storm. The mortality rates also differ across the globe, ranging from 0.5-13%.…

COVID-19 has affected the world tremendously. It is critical that biological experiments and clinical designs are informed by computational approaches for time- and cost-effective solutions. Comparative analyses particularly can play a key…

Biomolecules · Quantitative Biology 2020-04-10 Goksel Misirli

Diagnosis of COVID-19 is necessary to prevent and control the disease. Deep learning methods have been considered a fast and accurate method. In this paper, by the parallel combination of three well-known pre-trained networks, we attempted…

Image and Video Processing · Electrical Eng. & Systems 2022-08-17 Faezeh Amouzegar , Hamid Mirvaziri , Mostafa Ghazizadeh-Ahsaee , Mahdi Shariatzadeh

Coronavirus Disease 2019 (COVID-19) is a rapidly emerging respiratory disease caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Due to the rapid human-to-human transmission of SARS-CoV-2, many healthcare systems…

Machine Learning · Computer Science 2020-12-01 Patrick Schwab , August DuMont Schütte , Benedikt Dietz , Stefan Bauer

The SARS-CoV-2 pandemic has added new urgency to the study of viral mechanisms of infection. But while vaccines offer a measure of protection against this specific outbreak, a new era of pandemics has been predicted. In addition to this,…

Biological Physics · Physics 2022-10-25 Betony Adams , Ilya Sinayskiy , Rienk van Grondelle , Francesco Petruccione

Due to SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2) being a novel virus, there are currently no known effective antiviral drugs capable of slowing its progress. To accelerate the discovery of potential drug candidates,…

Biomolecules · Quantitative Biology 2020-09-29 Lokesh Agrawal , Thanasis Poullikkas , Scott Eisenhower , Carlo Monsanto , Ranjith Kumar Bakku

The SARS-CoV-2 virus and COVID-19 disease have posed unprecedented and overwhelming demand, challenges and opportunities to domain, model and data driven modeling. This paper provides a comprehensive review of the challenges, tasks,…

Computers and Society · Computer Science 2021-08-05 Longbing Cao , Qing Liu

With the ongoing global pandemic of coronavirus disease 2019 (COVID-19), there is an increasing quest for more accessible, easy-to-use, rapid, inexpensive, and high accuracy diagnostic tools. Traditional disease diagnostic methods such as…

SARS-CoV-2 is a severe respiratory infection that infects humans. Its outburst entitled it as a pandemic emergence. To get a grip on this, outbreak specific preventive and therapeutic interventions are urgently needed. It must be said that,…

Quantitative Methods · Quantitative Biology 2020-05-07 Giulia Russo , Marzio Pennisi , Marco Viceconti , Francesco Pappalardo

Mathematical models describing SARS-CoV-2 dynamics and the corresponding immune responses in patients with COVID-19 can be critical to evaluate possible clinical outcomes of antiviral treatments. In this work, based on the concept of virus…

Summary: Polymerase chain reaction-based assays are the current gold standard for detecting and diagnosing SARS-CoV-2. However, as SARS-CoV-2 mutates, we need to constantly assess whether existing PCR-based assays will continue to detect…