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Pathological speech analysis has been of interest in the detection of certain diseases like depression and Alzheimer's disease and attracts much interest from researchers. However, previous pathological speech analysis models are commonly…

Audio and Speech Processing · Electrical Eng. & Systems 2024-11-08 Fei Yang , Xuenan Xu , Mengyue Wu , Kai Yu

Parkinson's disease (PD) is a neuro-degenerative disorder that affects movement, speech, and coordination. Timely diagnosis and treatment can improve the quality of life for PD patients. However, access to clinical diagnosis is limited in…

Computer Vision and Pattern Recognition · Computer Science 2024-02-19 Md. Zarif Ul Alam , Md Saiful Islam , Ehsan Hoque , M Saifur Rahman

Objective: We present the PaHaW Parkinson's disease handwriting database, consisting of handwriting samples from Parkinson's disease (PD) patients and healthy controls. Our goal is to show that kinematic features and pressure features in…

Computer Vision and Pattern Recognition · Computer Science 2024-11-06 Peter Drotár , Jiří Mekyska , Irena Rektorová , Lucia Masarová , Zdeněk Smékal , Marcos Faundez-Zanuy

Parkinson's disease (PD) is a slowly progressing neurodegenerative disease with early manifestation of motor signs. Objective measurements of motor signs are of vital importance for diagnosing, monitoring and developing disease modifying…

Alzheimer's Disease (AD) is nowadays the most common form of dementia, and its automatic detection can help to identify symptoms at early stages, so that preventive actions can be carried out. Moreover, non-intrusive techniques based on…

Computation and Language · Computer Science 2020-11-21 Mireia Farrús , Joan Codina-Filbà

Oculomotor alterations constitute a promising biomarker to detect and characterize Parkinson's disease (PD), even in prodromal stages. Currently, only global and simplified eye movement trajectories are employed to approximate the complex…

Computer Vision and Pattern Recognition · Computer Science 2025-02-26 Juan Niño , Luis Guayacán , Santiago Gómez , Fabio Martínez

Recent advances in Artificial Intelligence (AI) and the exploration of noninvasive, objective biomarkers, such as speech signals, have encouraged the development of algorithms to support the early diagnosis of neurodegenerative diseases,…

In this study, we executed a genomic analysis with the objective of selecting a set of genes (possibly small) that would help in the detection and classification of samples from patients affected by Parkinson Disease. We performed a…

Machine Learning · Computer Science 2016-02-24 Giancarlo Crocetti , Michael Coakley , Phil Dressner , Wanda Kellum , Tamba Lamin

Parkinson's disease (PD) poses a growing global health challenge, with Bangladesh experiencing a notable rise in PD-related mortality. Early detection of PD remains particularly challenging in resource-constrained settings, where…

Machine Learning · Computer Science 2025-05-20 Riad Hossain , Muhammad Ashad Kabir , Arat Ibne Golam Mowla , Animesh Chandra Roy , Ranjit Kumar Ghosh

Memory disorders are a central factor in the decline of functioning and daily activities in elderly individuals. The confirmation of the illness, initiation of medication to slow its progression, and the commencement of occupational therapy…

Sound · Computer Science 2024-02-08 Marko Niemelä , Mikaela von Bonsdorff , Sami Äyrämö , Tommi Kärkkäinen

In this paper, we present a speaker-independent dysarthric speech recognition system, with a focus on evaluating the recently released Speech Accessibility Project (SAP-1005) dataset, which includes speech data from individuals with…

Alzheimer's disease (AD) is a common form of dementia that severely impacts patient health. As AD impairs the patient's language understanding and expression ability, the speech of AD patients can serve as an indicator of this disease. This…

Audio and Speech Processing · Electrical Eng. & Systems 2023-07-07 Hongmin Cai , Xiaoke Huang , Zhengliang Liu , Wenxiong Liao , Haixing Dai , Zihao Wu , Dajiang Zhu , Hui Ren , Quanzheng Li , Tianming Liu , Xiang Li

Objective: Voice disorders significantly compromise individuals' ability to speak in their daily lives. Without early diagnosis and treatment, these disorders may deteriorate drastically. Thus, automatic classification systems at home are…

Audio and Speech Processing · Electrical Eng. & Systems 2023-04-27 Heng-Cheng Kuo , Yu-Peng Hsieh , Huan-Hsin Tseng , Chi-Te Wang , Shih-Hau Fang , Yu Tsao

Real-world digital Parkinson's disease assessment faces challenges such as heterogeneous modalities, cross-device bias, and incomplete labeling. Existing methods often focus on average predictive performance, lacking the reliability…

Machine Learning · Computer Science 2026-05-12 Wenbin Wei , Ruixiang Gao , Suyuan Yao , Xuanzhen Zhao , Cheng Huang , Hen-Wei Huang

Parkinson's disease (PD) belongs to the class of neurodegenerative disorders that affect the central nervous system. It is usually defined as the gradual loss of dopaminergic neurons in the substantia nigra pars compacta, which causes both…

Neurons and Cognition · Quantitative Biology 2024-11-01 Hina Shaheen , Roderick Melnik

Alzheimer's disease (AD) is a progressive neurodegenerative disease and recently attracts extensive attention worldwide. Speech technology is considered a promising solution for the early diagnosis of AD and has been enthusiastically…

Audio and Speech Processing · Electrical Eng. & Systems 2021-10-05 Ying Qin , Wei Liu , Zhiyuan Peng , Si-Ioi Ng , Jingyu Li , Haibo Hu , Tan Lee

We developed dysarthric speech intelligibility classifiers on 551,176 disordered speech samples contributed by a diverse set of 468 speakers, with a range of self-reported speaking disorders and rated for their overall intelligibility on a…

Audio and Speech Processing · Electrical Eng. & Systems 2023-03-17 Subhashini Venugopalan , Jimmy Tobin , Samuel J. Yang , Katie Seaver , Richard J. N. Cave , Pan-Pan Jiang , Neil Zeghidour , Rus Heywood , Jordan Green , Michael P. Brenner

Understanding how individuals with Parkinson's disease (PD) describe cognitive experiences in their daily lives can offer valuable insights into disease-related cognitive and emotional changes. However, extracting such information from…

Computation and Language · Computer Science 2025-11-13 Varada Khanna , Nilay Bhatt , Ikgyu Shin , Sule Tinaz , Yang Ren , Hua Xu , Vipina K. Keloth

With the development of digital technology, machine learning has paved the way for the next generation of tinnitus diagnoses. Although machine learning has been widely applied in EEG-based tinnitus analysis, most current models are…

Signal Processing · Electrical Eng. & Systems 2022-05-09 Yun Li , Zhe Liu , Lina Yao , Molly Lucas , Jessica J. M. Monaghan , Yu Zhang

Parkinson's disease (PD) is a progressive neurological disorder primarily affecting motor function resulting in tremor at rest, rigidity, bradykinesia, and postural instability. The physical severity of PD impairments can be quantified…

Computer Vision and Pattern Recognition · Computer Science 2020-07-20 Mandy Lu , Kathleen Poston , Adolf Pfefferbaum , Edith V. Sullivan , Li Fei-Fei , Kilian M. Pohl , Juan Carlos Niebles , Ehsan Adeli
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