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Consider a big data multiple testing task, where, due to storage and computational bottlenecks, one is given a very large collection of p-values by splitting into manageable chunks and distributing over thousands of computer nodes. This…

Methodology · Statistics 2018-05-08 Subhadeep Mukhopadhyay

In this paper we present an unsupervised method to learn the weights with which the scores of multiple classifiers must be combined in classifier fusion settings. We also introduce a novel metric for ranking instances based on an index…

Machine Learning · Computer Science 2015-02-09 Anurag Kumar , Bhiksha Raj

Data-driven most powerful tests are statistical hypothesis decision-making tools that deliver the greatest power against a fixed null hypothesis among all corresponding data-based tests of a given size. When the underlying data…

Statistics Theory · Mathematics 2023-03-15 Albert Vexler , Alan D. Hutson

Multiple heterogeneous data sources are becoming increasingly available for statistical analyses in the era of big data. As an important example in finite-population inference, we develop a unified framework of the test-and-pool approach to…

Methodology · Statistics 2023-05-30 Chenyin Gao , Shu Yang

Diagnostic test accuracy studies observe the result of a gold standard procedure that defines the presence or absence of a disease and the result of a diagnostic test. They typically report the number of true positives, false positives,…

Methodology · Statistics 2020-08-19 Aristidis K. Nikoloulopoulos

Equivalence tests, otherwise known as parity or similarity tests, are frequently used in ``bioequivalence studies" to establish practical equivalence rather than the usual statistical significant difference. In this article, we propose an…

Methodology · Statistics 2025-07-29 Daniel Ochieng

The literature on hypothesis testing with data-dependent and post-hoc significance levels relies on a particular extension of the Type-I error to data-dependent levels. Existing arguments for this extension are heuristic, and primarily…

Statistics Theory · Mathematics 2026-05-28 Nick W. Koning

Permutation tests enable testing statistical hypotheses in situations when the distribution of the test statistic is complicated or not available. In some situations, the test statistic under investigation is multivariate, with the multiple…

Methodology · Statistics 2023-11-08 Zdeněk Hlávka , Daniel Hlubinka , Šárka Hudecová

Unmeasured confounding, selection bias, and measurement error are well-known sources of bias in epidemiologic research. Methods for assessing these biases have their own limitations. Many quantitative sensitivity analysis approaches…

Methodology · Statistics 2021-08-11 Louisa H. Smith , Maya B. Mathur , Tyler J. VanderWeele

We study the problem of multiple hypothesis testing for multidimensional data when inter-correlations are present. The problem of multiple comparisons is common in many applications. When the data is multivariate and correlated, existing…

Statistics Theory · Mathematics 2015-06-02 Mahdis Azadbakhsh , Xin Gao , Hanna Jankowski

We investigate a generalized empirical likelihood approach in a two-group setting where the constraints on parameters have a form of U-statistics. In this situation, the summands that consist of the constraints for the empirical likelihood…

Methodology · Statistics 2015-05-04 Jihnhee Yu , Luge Yang , Albert Vexler , Alan D. Hutson

For a given testing problem, let $U_1,...,U_n$ be individually valid and conditionally on the data i.i.d.\ P-variables (often called P-values). For example, the data could come in groups, and each $U_i$ could be based on subsampling just…

Methodology · Statistics 2011-08-22 Lutz Mattner

This article proposes an alternative to the Hosmer-Lemeshow (HL) test for evaluating the calibration of probability forecasts for binary events. The approach is based on e-values, a new tool for hypothesis testing. An e-value is a random…

Methodology · Statistics 2023-02-28 Alexander Henzi , Marius Puke , Timo Dimitriadis , Johanna Ziegel

There is a useful counterpart of conformal prediction for e-values, called conformal e-prediction. Conformal prediction can serve as basis for testing the assumption of exchangeability, leading to conformal testing. Similarly, conformal…

Statistics Theory · Mathematics 2024-11-05 Vladimir Vovk , Ilia Nouretdinov , Alex Gammerman

Significance testing based on p-values has been implicated in the reproducibility crisis in scientific research, with one of the proposals being to eliminate them in favor of Bayesian analyses. Defenders of the p-values have countered that…

Methodology · Statistics 2023-05-02 Christos Argyropoulos , Andy P Grieve

We consider the problem of testing for treatment effect heterogeneity in observational studies, and propose a nonparametric test based on multisample U-statistics. To account for potential confounders, we use reweighted data where the…

Methodology · Statistics 2021-03-30 Maozhu Dai , Weining Shen , Hal S. Stern

Correlated observations are ubiquitous phenomena in a plethora of scientific avenues. Tackling this dependence among test statistics has been one of the pertinent problems in simultaneous inference. However, very little literature exists…

Statistics Theory · Mathematics 2024-11-20 Monitirtha Dey

In this paper we introduce a novel procedure for improving multiple testing procedures (MTPs) under scenarios when the null hypothesis $p$-values tend to be stochastically larger than standard uniform (referred to as 'inflated'). An…

Methodology · Statistics 2025-08-29 Jules L. Ellis , Jakub Pecanka , Jelle Goeman

We are concerned with a situation in which we would like to test multiple hypotheses with tests whose p-values cannot be computed explicitly but can be approximated using Monte Carlo simulation. This scenario occurs widely in practice. We…

Methodology · Statistics 2018-10-17 Axel Gandy , Georg Hahn

Both, Bayes Theorem and the cMPE-Method serve for establishing relations between systems of probabilities. By the cMPE-Method non-conditional probabilities are added, by the DPE-Method, they are subtracted, however, in both versions…

Statistics Theory · Mathematics 2007-06-13 R. Gottlob