Related papers: Raman Spectroscopy and Machine Learning-based Opti…
Identifying pathogens in complex samples such as blood, urine, and wastewater is critical to detect infection and inform optimal treatment. Surface-enhanced Raman spectroscopy (SERS) and machine learning (ML) can distinguish among multiple…
Diabetic Retinopathy (DR) is a serious and common complication of diabetes, caused by prolonged high blood sugar levels that damage the small retinal blood vessels. If left untreated, DR can progress to retinal vein occlusion and stimulate…
Early and accurate detection of Parkinson's disease (PD) is a crucial diagnostic challenge carrying immense clinical significance, for effective treatment regimens and patient management. For instance, a group of subjects termed SWEDD who…
We have developed a coherent Raman imaging platform using broadband coherent anti-Stokes Raman scattering (BCARS) that provides an unprecedented combination of speed, sensitivity, and spectral breadth. The system utilizes a unique…
Artificial intelligence (AI) systems can detect disease-related acoustic patterns in cough sounds, offering a scalable and cost-effective approach to tuberculosis (TB) screening in high-burden, resource-limited settings. Previous studies…
Parkinson's disease is a widespread neurodegenerative condition necessitating early diagnosis for effective intervention. This paper introduces an innovative method for diagnosing Parkinson's disease through the analysis of human EEG…
Identification of abnormalities in red blood cells (RBC) is key to diagnosing a range of medical conditions from anaemia to liver disease. Currently this is done manually, a time-consuming and subjective process. This paper presents an…
Cancer is the second leading cause of death in the world. Diagnosing cancer early on can save many lives. Pathologists have to look at tissue microarray (TMA) images manually to identify tumors, which can be time-consuming, inconsistent and…
In this paper, we propose a standardized framework for automatic tuberculosis (TB) detection from cough audio and routinely collected clinical data using machine learning. While TB screening from audio has attracted growing interest,…
The motivation of this work is the use of non-invasive and low cost techniques to obtain a faster and more accurate diagnosis of systemic sclerosis (SSc), rheumatic, autoimmune, chronic and rare disease. The technique in question is Near…
Label-free vibrational imaging by stimulated Raman scattering (SRS) provides unprecedented insight into real-time chemical distributions in living systems. Specifically, SRS in the fingerprint region can resolve multiple chemicals in a…
Tuberculosis remains a critical global health issue, particularly in resource-limited and remote areas. Early detection is vital for treatment, yet the lack of skilled radiologists underscores the need for artificial intelligence…
Tuberculosis (TB) is a top-10 cause of death worldwide. Though the WHO recommends chest radiographs (CXRs) for TB screening, the limited availability of CXR interpretation is a barrier. We trained a deep learning system (DLS) to detect…
Tuberculosis relapse is a barrier to shorter treatment. It is thought that lipid rich cells, phenotypically resistant to antibiotics, may play a major role. Most studies investigating relapse use sputum samples although tissue bacteria may…
This study investigates the application of surface-enhanced Raman spectroscopy (SERS) as a diagnostic tool for myasthenia gravis, a severe neuromuscular disorder characterized by muscle weakness and fatigue. Blood serum samples were…
Glaucoma leads to permanent vision disability by damaging the optical nerve that transmits visual images to the brain. The fact that glaucoma does not show any symptoms as it progresses and cannot be stopped at the later stages, makes it…
Bacteraemia, a bloodstream infection with high morbidity and mortality rates, poses significant diagnostic challenges. Accurate diagnosis through blood cultures is resource-intensive. Developing a machine learning model to predict blood…
Tuberculosis (TB) is the leading cause of death from an infectious disease globally, with the highest burden in low- and middle-income countries. In these regions, limited healthcare access and high patient-to-provider ratios impede…
Theranostics, the combination of diagnosis and therapy, has long held promise as a means to achieving personalised precision cancer treatments. However, despite its potential, theranostics has yet to realise significant clinical…
Parkinson's disease (PD) is a degenerative and progressive neurological condition. Early diagnosis can improve treatment for patients and is performed through dopaminergic imaging techniques like the SPECT DaTscan. In this study, we propose…