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While micro-CT systems are instrumental in preclinical research, clinical micro-CT imaging has long been desired with cochlear implantation as a primary example. The structural details of the cochlear implant and the temporal bone require a…
Strong speckle noise is inherent to optical coherence tomography (OCT) imaging and represents a significant obstacle for accurate quantitative analysis of retinal structures which is key for advances in clinical diagnosis and monitoring of…
Echocardiogram is the most commonly used imaging modality in cardiac assessment duo to its non-invasive nature, real-time capability, and cost-effectiveness. Despite its advantages, most clinical echocardiograms provide only two-dimensional…
Quantitative estimation of contrast agent concentration is made possible by spectral CT and material decomposition. There are several approaches to modulate the sensitivity of the imaging system to obtain the different spectral channels…
Three-dimensional coronary magnetic resonance angiography (CMRA) demands reconstruction algorithms that can significantly suppress the artifacts from a heavily undersampled acquisition. While unrolling-based deep reconstruction methods have…
Advanced atherosclerosis in the coronary arteries is one of the leading causes of deaths worldwide while being preventable and treatable. In order to image atherosclerotic lesions (plaque), intravascular optical coherence tomography (IVOCT)…
Motion-compensated MR reconstruction (MCMR) is a powerful concept with considerable potential, consisting of two coupled sub-problems: Motion estimation, assuming a known image, and image reconstruction, assuming known motion. In this work,…
The reconstruction of three-dimensional models of coronary arteries is of great significance for the localization, evaluation and diagnosis of stenosis and plaque in the arteries, as well as for the assisted navigation of interventional…
Speckle is an intrinsic pattern in optical coherence tomography (OCT) that obscures fine image features and degrades effective resolution. In this study, we propose a numerical speckle reduction method based on the dispersed scatterer model…
The segmentation and classification of cardiac magnetic resonance imaging are critical for diagnosing heart conditions, yet current approaches face challenges in accuracy and generalizability. In this study, we aim to further advance the…
Artifacts in kilo-Voltage CT (kVCT) imaging degrade image quality, impacting clinical decisions. We propose a deep learning framework for metal artifact reduction (MAR) and domain transformation from kVCT to Mega-Voltage CT (MVCT). The…
In this work, we proposed a continuous-acquisition strategy using a gradient echo (GRE) inversion recovery sequence based on spiral trajectories to simultaneously obtain the $T_1$ mapping and CINE imaging. The acquisition is using a…
Automatically identifying the structural substrates underlying cardiac abnormalities can potentially provide real-time guidance for interventional procedures. With the knowledge of cardiac tissue substrates, the treatment of complex…
Deep fully convolutional neural network (FCN) based architectures have shown great potential in medical image segmentation. However, such architectures usually have millions of parameters and inadequate number of training samples leading to…
In cardiac magnetic resonance imaging, fully-automatic segmentation of the heart enables precise structural and functional measurements to be taken, e.g. from short-axis MR images of the left-ventricle. In this work we propose a recurrent…
Optical coherence tomography (OCT) is a high-resolution three-dimensional imaging technique that enables non-destructive measurements of surface and subsurface microstructures. Recent developments of OCT operating in the mid-infrared (MIR)…
In recent years, machine learning (ML) based reconstruction has been widely investigated and employed in cardiac magnetic resonance (CMR) imaging. ML-based reconstructions can deliver clinically acceptable image quality under substantially…
We present a deep learning framework for volumetric speckle reduction in optical coherence tomography (OCT) based on a conditional generative adversarial network (cGAN) that leverages the volumetric nature of OCT data. In order to utilize…
Estimating the shape and motion state of the myocardium is essential in diagnosing cardiovascular diseases.However, cine magnetic resonance (CMR) imaging is dominated by 2D slices, whose large slice spacing challenges inter-slice shape…
X-ray computed microtomography ({\mu}-CT) is a non-destructive technique that can generate high-resolution 3D images of the internal anatomy of medical and biological samples. These images enable clinicians to examine internal anatomy and…