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Coronavirus Disease 2019 (COVID-19) spread globally in early 2020, causing the world to face an existential health crisis. Automated detection of lung infections from computed tomography (CT) images offers a great potential to augment the…

Image and Video Processing · Electrical Eng. & Systems 2020-05-25 Deng-Ping Fan , Tao Zhou , Ge-Peng Ji , Yi Zhou , Geng Chen , Huazhu Fu , Jianbing Shen , Ling Shao

This work introduces a novel epidemiological model that simultaneously considers multiple viral strains, reinfections due to waning immunity response over time and an optimal control formulation. This enables us to derive optimal mitigation…

Systems and Control · Electrical Eng. & Systems 2021-09-10 Edilson F. Arruda , Dayse H. Pastore , Clauda M. Dias , Shyam S. Das

The fast transmission rate of COVID-19 worldwide has made this virus the most important challenge of year 2020. Many mitigation policies have been imposed by the governments at different regional levels (country, state, county, and city) to…

Applications · Statistics 2022-05-04 Yue Bai , Abolfazl Safikhani , George Michailidis

The COVID-19 pandemic has proved to be one of the most disruptive public health emergencies in recent memory. Among non-pharmaceutical interventions, social distancing and lockdown measures are some of the most common tools employed by…

Dynamical Systems · Mathematics 2021-02-16 Carl Corcoran , John Michael Clark

Capturing the structured mixing within a population is key to the reliable projection of infectious disease dynamics and hence informed control. Both heterogeneity in the number of contacts and age-structured mixing have been repeatedly…

Social and Information Networks · Computer Science 2026-03-17 Luke Murray Kearney , Emma L Davis , Matt J Keeling

This paper introduces a new optimal control model to describe and control the dynamics of infectious diseases. In the present model, the average time of isolation (i.e. hospitalization) of infectious population is the main time-dependent…

Optimization and Control · Mathematics 2015-05-06 Robin J. Evans , Musa Mammadov

The special epistemic characteristics of the COVID-19, such as the long incubation period and the infection through asymptomatic cases, put severe challenge to the containment of its outbreak. By the end of March 2020, China has…

Populations and Evolution · Quantitative Biology 2020-09-07 Xiaoqi Zhang , Zheng Ji , Yanqiao Zheng , Xinyue Ye , Dong Li

Consistent segmentation of COVID-19 patient's CT scans across multiple time points is essential to assess disease progression and response to therapy accurately. Existing automatic and interactive segmentation models for medical images only…

Image and Video Processing · Electrical Eng. & Systems 2023-06-02 Michelle Xiao-Lin Foo , Seong Tae Kim , Magdalini Paschali , Leili Goli , Egon Burian , Marcus Makowski , Rickmer Braren , Nassir Navab , Thomas Wendler

Real epidemic spreading networks often composed of several kinds of networks interconnected with each other, and the interrelated networks have the different topologies and epidemic dynamics. Moreover, most human diseases are derived from…

Physics and Society · Physics 2017-06-21 Zhongpu Xu , Xinchu Fu

The screening testing is an effective tool to control the early spread of an infectious disease such as COVID-19. When the total testing capacity is limited, we aim to optimally allocate testing resources among n counties. We build a…

Methodology · Statistics 2022-03-28 Yaxuan Huang , Zheng Tracy Ke , Jiashun Jin

The COVID-19 epidemic that emerged in Wuhan China at the end of 2019 hit Italy particularly hard, yielding the implementation of strict national lockdown rules (Phase 1). There is now a hot ongoing debate in Italy and abroad on what the…

In this paper, a mathematical model is proposed to analyze the dynamic behavior of COVID-19. Based on inter-city networked coupling effects, a fractional-order SEIHDR system with the real-data from 23 January to 18 March, 2020 of COVID-19…

Physics and Society · Physics 2020-05-01 Zhenzhen Lu , Yongguang Yu , YangQuan Chen , Guojian Ren , Conghui Xu , Shuhui Wang , Zhe Yin

Epidemics occur in all shapes and forms: infections propagating in our sparse sexual networks, rumours and diseases spreading through our much denser social interactions, or viruses circulating on the Internet. With the advent of large…

Physics and Society · Physics 2013-09-02 Laurent Hébert-Dufresne , Antoine Allard , Jean-Gabriel Young , Louis J. Dubé

To curb the spread of COVID-19, many governments around the world have implemented tiered lockdowns with varying degrees of stringency. Lockdown levels are typically increased when the disease spreads and reduced when the disease abates. A…

Populations and Evolution · Quantitative Biology 2020-11-16 Laurentz E. Olivier , Stefan Botha , Ian K. Craig

As a common strategy of contagious disease containment, lockdowns will inevitably weaken the economy. The ongoing COVID-19 pandemic underscores the trade-off arising from public health and economic cost. An optimal lockdown policy to…

Optimization and Control · Mathematics 2022-01-26 Qianqian Ma , Yang-Yu Liu , Alex Olshevsky

The outbreak of a pandemic, such as COVID-19, causes major health crises worldwide. Typical measures to contain the rapid spread usually include effective vaccination and strict interventions (Nature Human Behaviour, 2021). Motivated by…

Social and Information Networks · Computer Science 2025-03-31 Gargi Bakshi , Sujoy Bhore , Suraj Shetiya

We propose a general Bayesian approach to modeling epidemics such as COVID-19. The approach grew out of specific analyses conducted during the pandemic, in particular an analysis concerning the effects of non-pharmaceutical interventions…

Applications · Statistics 2021-01-01 Samir Bhatt , Neil Ferguson , Seth Flaxman , Axel Gandy , Swapnil Mishra , James A. Scott

Multiple lines of evidence strongly suggest that infection hotspots, where a single individual infects many others, play a key role in the transmission dynamics of COVID-19. However, most of the existing epidemiological models fail to…

The COVID-19 crisis has shown that we can only prevent the risk of mass contagion through timely, large-scale, coordinated, and decisive actions. However, frequently the models used by experts [from whom decision-makers get their main…

Applications · Statistics 2021-03-08 Mauricio Herrera

The adoption of containment measures to reduce the amplitude of the epidemic peak is a key aspect in tackling the rapid spread of an epidemic. Classical compartmental models must be modified and studied to correctly describe the effects of…

Populations and Evolution · Quantitative Biology 2021-05-18 G. Albi , L. Pareschi , M. Zanella