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Tracking of plant cells in images obtained by microscope is a challenging problem due to biological phenomena such as large number of cells, non-uniform growth of different layers of the tightly packed plant cells and cell division.…

Computer Vision and Pattern Recognition · Computer Science 2023-09-22 Md Shazid Islam , Arindam Dutta , Calvin-Khang Ta , Kevin Rodriguez , Christian Michael , Mark Alber , G. Venugopala Reddy , Amit K. Roy-Chowdhury

Single-cell RNA sequencing (scRNA-seq), especially temporally resolved datasets, enables genome-wide profiling of gene expression dynamics at single-cell resolution across discrete time points. However, current technologies provide only…

Genomics · Quantitative Biology 2025-11-19 Yue Ling , Peiqi Zhang , Zhenyi Zhang , Peijie Zhou

Cell segmentation is a major bottleneck in extracting quantitative single-cell information from microscopy data. The challenge is exasperated in the setting of microstructured environments. While deep learning approaches have proven useful…

Quantitative Methods · Quantitative Biology 2021-01-08 Tim Prangemeier , Christian Wildner , André O. Françani , Christoph Reich , Heinz Koeppl

Tracking living cells in video sequence is difficult, because of cell morphology and high similarities between cells. Tracking-by-detection methods are widely used in multi-cell tracking. We perform multi-cell tracking based on the cell…

Computer Vision and Pattern Recognition · Computer Science 2019-06-27 Zibin Zhou , Fei Wang , Wenjuan Xi , Huaying Chen , Peng Gao , Chengkang He

We propose a 3D convolutional neural network to simultaneously segment and detect cell nuclei in confocal microscopy images. Mirroring the co-dependency of these tasks, our proposed model consists of two serial components: the first part…

Image and Video Processing · Electrical Eng. & Systems 2018-09-07 Sundaresh Ram , Vicky T. Nguyen , Kirsten H. Limesand , Mert R. Sabuncu

This paper studies the fast adaptive beamforming for the multiuser multiple-input single-output downlink. Existing deep learning-based approaches assume that training and testing channels follow the same distribution which causes task…

Information Theory · Computer Science 2021-09-21 Juping Zhang , Yi Yuan , Gan Zheng , Ioannis Krikidis , Kai-Kit Wong

Cell counting is a ubiquitous, yet tedious task that would greatly benefit from automation. From basic biological questions to clinical trials, cell counts provide key quantitative feedback that drive research. Unfortunately, cell counting…

Computer Vision and Pattern Recognition · Computer Science 2018-03-02 Carlos X. Hernández , Mohammad M. Sultan , Vijay S. Pande

This paper presents a new deep regression model, which we call DeepDistance, for cell detection in images acquired with inverted microscopy. This model considers cell detection as a task of finding most probable locations that suggest cell…

Computer Vision and Pattern Recognition · Computer Science 2019-08-30 Can Fahrettin Koyuncu , Gozde Nur Gunesli , Rengul Cetin-Atalay , Cigdem Gunduz-Demir

We propose an automatic preprocessing and ensemble learning for segmentation of cell images with low quality. It is difficult to capture cells with strong light. Therefore, the microscopic images of cells tend to have low image quality but…

Image and Video Processing · Electrical Eng. & Systems 2021-08-31 Sota Kato , Kazuhiro Hotta

There is large consent that successful training of deep networks requires many thousand annotated training samples. In this paper, we present a network and training strategy that relies on the strong use of data augmentation to use the…

Computer Vision and Pattern Recognition · Computer Science 2015-05-19 Olaf Ronneberger , Philipp Fischer , Thomas Brox

Volumetric cell segmentation in fluorescence microscopy images is important to study a wide variety of cellular processes. Applications range from the analysis of cancer cells to behavioral studies of cells in the embryonic stage. Like in…

Image and Video Processing · Electrical Eng. & Systems 2022-11-29 Royden Wagner , Karl Rohr

Cell and nucleus segmentation are fundamental tasks for quantitative bioimage analysis. Despite progress in recent years, biologists and other domain experts still require novel algorithms to handle increasingly large and complex real-world…

Computer Vision and Pattern Recognition · Computer Science 2024-08-29 Thibaut Goldsborough , Ben Philps , Alan O'Callaghan , Fiona Inglis , Leo Leplat , Andrew Filby , Hakan Bilen , Peter Bankhead

Tracking segmentation masks of multiple instances has been intensively studied, but still faces two fundamental challenges: 1) the requirement of large-scale, frame-wise annotation, and 2) the complexity of two-stage approaches. To resolve…

Computer Vision and Pattern Recognition · Computer Science 2021-04-02 Yang Fu , Sifei Liu , Umar Iqbal , Shalini De Mello , Humphrey Shi , Jan Kautz

Spectral Embedding (SE) has often been used to map data points from non-linear manifolds to linear subspaces for the purpose of classification and clustering. Despite significant advantages, the subspace structure of data in the original…

Computer Vision and Pattern Recognition · Computer Science 2023-05-16 Hira Yaseen , Arif Mahmood

Semantic segmentation is a computer vision task that associates a label with each pixel in an image. Modern approaches tend to introduce class embeddings into semantic segmentation for deeply utilizing category semantics, and regard…

Computer Vision and Pattern Recognition · Computer Science 2023-08-25 Yuhe Liu , Chuanjian Liu , Kai Han , Quan Tang , Zengchang Qin

Segmentation has been a major task in neuroimaging. A large number of automated methods have been developed for segmenting healthy and diseased brain tissues. In recent years, deep learning techniques have attracted a lot of attention as a…

Image and Video Processing · Electrical Eng. & Systems 2019-07-05 Jimit Doshi , Guray Erus , Mohamad Habes , Christos Davatzikos

Recent works on representation learning for graph structured data predominantly focus on learning distributed representations of graph substructures such as nodes and subgraphs. However, many graph analytics tasks such as graph…

Artificial Intelligence · Computer Science 2017-07-18 Annamalai Narayanan , Mahinthan Chandramohan , Rajasekar Venkatesan , Lihui Chen , Yang Liu , Shantanu Jaiswal

Spectral clustering is a leading clustering method. Two of its major shortcomings are the disjoint optimization process and the limited representation capacity. To address these issues, we propose a deep spectral clustering model (named…

Computer Vision and Pattern Recognition · Computer Science 2025-08-07 Wengang Guo , Wei Ye , Chunchun Chen , Xin Sun , Christian Böhm , Claudia Plant , Susanto Rahardja

We address the problem of acoustic source separation in a deep learning framework we call "deep clustering." Rather than directly estimating signals or masking functions, we train a deep network to produce spectrogram embeddings that are…

Neural and Evolutionary Computing · Computer Science 2015-08-19 John R. Hershey , Zhuo Chen , Jonathan Le Roux , Shinji Watanabe

The goal of metric learning is to learn a function that maps samples to a lower-dimensional space where similar samples lie closer than dissimilar ones. Particularly, deep metric learning utilizes neural networks to learn such a mapping.…

Computer Vision and Pattern Recognition · Computer Science 2021-06-14 Jenny Seidenschwarz , Ismail Elezi , Laura Leal-Taixé