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Purpose: Target delineation for radiation therapy is a time-consuming and complex task. Autocontouring gross tumor volumes (GTVs) has been shown to increase efficiency. However, there is limited literature on post-operative target…

We give a scenario-based treatment plan optimization formulation that is equivalent to planning with geometric margins if the scenario doses are calculated using the static dose cloud approximation. If the scenario doses are instead…

Medical Physics · Physics 2016-03-23 Albin Fredriksson , Rasmus Bokrantz

In this paper, we present a new method to generate an instantaneous volumetric image using a single x-ray projection. To fully extract motion information hidden in projection images, we partitioned a projection image into small patches. We…

Medical Physics · Physics 2017-02-08 Yuan Xu , Hao Yan , Luo Ouyang , Jing Wang , Linghong Zhou , Laura Cervino , Steve B. Jiang , Xun Jia

Personalized medicine is the future of medical practice. In oncology, tumor heterogeneity assessment represents a pivotal step for effective treatment planning and prognosis prediction. Despite new procedures for DNA sequencing and…

Bootstrap is a principled and powerful frequentist statistical tool for uncertainty quantification. Unfortunately, standard bootstrap methods are computationally intensive due to the need of drawing a large i.i.d. bootstrap sample to…

Machine Learning · Computer Science 2022-09-02 Mao Ye , Qiang Liu

Proton therapy is a cancer treatment technique currently in growth worldwide. It offers advantages with respect to conventional X-ray and $\gamma$-ray radiotherapy, in particular, a better control of the dose deposition allowing to reach a…

A challenge in high-dimensional inverse problems is developing iterative solvers to find the accurate solution of regularized optimization problems with low computational cost. An important example is computed tomography (CT) where both…

Numerical Analysis · Mathematics 2024-12-16 Alessandro Perelli , Carola-Bibiane Schonlieb , Matthias J. Ehrhardt

Objective evaluation of new and improved methods for PET imaging requires access to images with ground truth, as can be obtained through simulation studies. However, for these studies to be clinically relevant, it is important that the…

This paper addresses the challenges of designing mesh convolution neural networks for 3D mesh dense prediction. While deep learning has achieved remarkable success in image dense prediction tasks, directly applying or extending these…

Computer Vision and Pattern Recognition · Computer Science 2024-08-27 Shi Hezi , Jiang Luo , Zheng Jianmin , Zeng Jun

Balancing the trade-off between safety and efficiency is of significant importance for path planning under uncertainty. Many risk-aware path planners have been developed to explicitly limit the probability of collision to an acceptable…

Robotics · Computer Science 2022-10-26 Fei Meng , Liangliang Chen , Han Ma , Jiankun Wang , Max Q. -H. Meng

Recently neural scene representations have provided very impressive results for representing 3D scenes visually, however, their study and progress have mainly been limited to visualization of virtual models in computer graphics or scene…

Computer Vision and Pattern Recognition · Computer Science 2022-09-26 Yassine Ahmine , Arnab Dey , Andrew I. Comport

We present a method of directly optimizing on deviations in clinical goal values in radiation therapy treatment planning. Using a new mathematical framework in which metrics derived from the dose-volume histogram are regarded as functionals…

Medical Physics · Physics 2021-09-07 Tianfang Zhang , Rasmus Bokrantz , Jimmy Olsson

Proton radiography is a technique extensively used to resolve magnetic field structures in high energy density plasmas, revealing a whole variety of interesting phenomena such as magnetic reconnection and collisionless shocks found in…

We propose a method to achieve the geometric calibration of cone-beam imaging and delivery systems in radiation therapy; our approach applies to devices where an X-ray source and a flat-panel detector, facing each other, move in circular…

Medical Physics · Physics 2007-05-23 Evangelos Matsinos , Wolfgang Kaissl

External beam X-ray therapy (XRT) and proton therapy (PT) are effective and widely accepted forms of treatment for many types of cancer. However, the procedures require extensive computerized planning. Current planning systems for both XRT…

Graphics · Computer Science 2018-11-30 Felix G. Hamza-Lup , Shane Farrar , Erik Leon

To improve the quality of cancer treatment with protons, a translation of X-ray Computed Tomography (CT) images into a map of the proton stopping powers needs to be more accurate. Proton stopping powers determined from CT images have…

The iso-frequency contours of a photonic crystal are important for predicting and understanding exotic optical phenomena that are not apparent from high-symmetry band structure visualizations. Here, we demonstrate a method to directly…

In post-operative radiotherapy for prostate cancer, the cancerous prostate gland has been surgically removed, so the clinical target volume (CTV) to be irradiated encompasses the microscopic spread of tumor cells, which cannot be visualized…

Radiotherapy inverse planning often requires planners to modify parameters in the treatment planning system's objective function to produce clinically acceptable plans. Due to the manual steps in this process, plan quality can vary…

Medical Physics · Physics 2022-05-11 Kelsey Maass , Aleksandr Aravkin , Minsun Kim

We study the problem of reconstructing an image from information stored at contour locations. We show that high-quality reconstructions with high fidelity to the source image can be obtained from sparse input, e.g., comprising less than…

Computer Vision and Pattern Recognition · Computer Science 2018-04-11 Tali Dekel , Chuang Gan , Dilip Krishnan , Ce Liu , William T. Freeman