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This survey paper focuses on modulation aspects of molecular communication, an emerging field focused on building biologically-inspired systems that embed data within chemical signals. The primary challenges in designing these systems are…

Emerging Technologies · Computer Science 2020-12-29 Mehmet Sukru Kuran , H. Birkan Yilmaz , Ilker Demirkol , Nariman Farsad , Andrea Goldsmith

A diffusion molecular channel is a channel with memory, as molecules released into the medium hit the receptors after a random delay. Coding over the diffusion channel is performed by choosing the type, intensity, or the released time of…

Within the domain of molecular communications, researchers mimic the techniques in nature to come up with alternative communication methods for collaborating nanomachines. This work investigates the channel transfer function for molecular…

Information Theory · Computer Science 2014-04-18 H. Birkan Yilmaz , Akif Cem Heren , Tuna Tugcu , Chan-Byoung Chae

Intracellular cargo transport can arise from passive diffusion, active motor-driven transport along cytoskeletal filament networks, and passive advection by fluid flows entrained by such motor/cargo motion. Active and advective transport…

Biological Physics · Physics 2012-07-24 P. Khuc Trong , J. Guck , R. E. Goldstein

In this paper, a simple memory limited transmitter for molecular communication is proposed, in which information is encoded in the diffusion rate of the molecules. Taking advantage of memory, the proposed transmitter reduces the ISI problem…

Information Theory · Computer Science 2014-10-30 Mohammad Movahednasab , Mehdi Soleimanifar , Amin Gohari , Masoumeh Nasiri Kenari , Urbashi Mitra

In this paper, a diffusion-based molecular communication channel between two nano-machines is considered. The effect of the amount of memory on performance is characterized, and a simple memory-limited decoder is proposed and its…

Biological Physics · Physics 2014-05-05 Reza Mosayebi , Hamidreza Arjmandi , Amin Gohari , Masoumeh Nasiri Kenari , Urbashi Mitra

Active transport such as fluid flow is sought in molecular communication to extend coverage, improve reliability, and mitigate interference. Flow models are often over-simplified, assuming one-dimensional diffusion with constant drift.…

Emerging Technologies · Computer Science 2024-10-30 Wayan Wicke , Tobias Schwering , Arman Ahmadzadeh , Vahid Jamali , Adam Noel , Robert Schober

One of the primary computational requirements of a cellular system is the ability to transfer information between spatially separated components. To accomplish this, biology uses diverse physical channels including production or release of…

Biological Physics · Physics 2023-08-11 Samuel Bryant , Benjamin Machta

In diffusion-based molecular communication, information particles locomote via a diffusion process, characterized by random movement and heavy tail distribution for the random arrival time. As a result, the molecular communication shows…

Emerging Technologies · Computer Science 2017-04-05 Changmin Lee , H. Birkan Yilmaz , Chan-Byoung Chae , Nariman Farsad , Andrea Goldsmith

In a diffusion-based molecular communication system, molecules are employed to convey information. When propagation and reception processes are considered in a framework of first passage processes, we need to focus on absorbing receivers.…

Emerging Technologies · Computer Science 2016-09-05 H. Birkan Yilmaz , Gee-Yong Suk , Chan-Byoung Chae

Morphogens are secreted signaling molecules that mediate tissue patterning and growth of embryonic tissues. They are secreted in a localized region and spread through the tissue to form a graded concentration profile. We present a…

Intercellular exchange networks are essential for the adaptive capabilities of populations of cells. While diffusional exchanges have traditionally been difficult to map, recent advances in nanotechnology enable precise probing of exchange…

Statistical Mechanics · Physics 2024-12-13 Luís C. F. Latoski , Andrea De Martino , Daniele De Martino

Spatial distributions of morphogens provide positional information in developing systems, but how the distributions are established and maintained remains an open problem. Transport by diffusion has been the traditional mechanism, but…

Cell Behavior · Quantitative Biology 2022-11-23 Jay A. Stotsky , Hans G. Othmer

In this paper, we propose adding enzymes to the propagation environment of a diffusive molecular communication system as a strategy for mitigating intersymbol interference. The enzymes form reaction intermediates with information molecules…

Information Theory · Computer Science 2014-10-17 Adam Noel , Karen C. Cheung , Robert Schober

The transport of particles in cells is influenced by the properties of intracellular networks they traverse while searching for localized target regions or reaction partners. Moreover, given the rapid turnover in many intracellular…

Biological Physics · Physics 2024-06-21 Lachlan Elam , Mónica C. Quiñones-Frías , Ying Zhang , Avital A. Rodal , Thomas G. Fai

Molecular communication emerges as a promising communication paradigm for nanotechnology. However, solid mathematical foundations for information-theoretic analysis of molecular communication have not yet been built. In particular, no one…

Information Theory · Computer Science 2013-11-19 Ya-Ping Hsieh , Ping-Cheng Yeh

Energy efficient information transmission may be relevant to biological sensory signal processing as well as to low power electronic devices. We explore its consequences in two different regimes. In an ``immediate'' regime, we argue that…

Statistical Mechanics · Physics 2007-05-23 Vijay Balasubramanian , Don Kimber , Michael J Berry

The reliable detection of environmental molecules in the presence of noise is an important cellular function, yet the underlying computational mechanisms are not well understood. We introduce a model of two interacting sensors which allows…

Biological Physics · Physics 2020-02-25 Vudtiwat Ngampruetikorn , David J. Schwab , Greg J. Stephens

Information molecules play a crucial role in molecular communication (MC), acting as carriers for information transfer. A common approach to get information molecules in MC involves harvesting them from the environment; however, the…

Information Theory · Computer Science 2025-08-08 Dongliang Jing , Linjuan Li , Zhen Cheng , Lin Lin , Andrew W. Eckford

Among the main actors of organism development there are morphogens, which are signaling molecules diffusing in the developing organism and acting on cells to produce local responses. Growth is thus determined by the distribution of such…

Optimization and Control · Mathematics 2016-09-21 Francesco Rossi , Nastassia Pouradier Duteil , Nir Yakoby , Benedetto Piccoli