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Medical question-answering (QA) systems can benefit from advances in large language models (LLMs), but directly applying LLMs to the clinical domain poses challenges such as maintaining factual accuracy and avoiding hallucinations. In this…

Computation and Language · Computer Science 2025-12-08 Tasnimul Hassan , Md Faisal Karim , Haziq Jeelani , Elham Behnam , Robert Green , Fayeq Jeelani Syed

Recent advancements in Large Language Models (LLMs) and Large Multi-modal Models (LMMs) have shown potential in various medical applications, such as Intelligent Medical Diagnosis. Although impressive results have been achieved, we find…

In Question Answering (QA), Retrieval Augmented Generation (RAG) has revolutionized performance in various domains. However, how to effectively capture multi-document relationships, particularly critical for biomedical tasks, remains an…

Computation and Language · Computer Science 2025-04-03 Lingxiao Guan , Yuanhao Huang , Jie Liu

Multimodal/vision language models (VLMs) are increasingly being deployed in healthcare settings worldwide, necessitating robust benchmarks to ensure their safety, efficacy, and fairness. Multiple-choice question and answer (QA) datasets…

We introduce MedXpertQA, a highly challenging and comprehensive benchmark to evaluate expert-level medical knowledge and advanced reasoning. MedXpertQA includes 4,460 questions spanning 17 specialties and 11 body systems. It includes two…

Artificial Intelligence · Computer Science 2025-06-09 Yuxin Zuo , Shang Qu , Yifei Li , Zhangren Chen , Xuekai Zhu , Ermo Hua , Kaiyan Zhang , Ning Ding , Bowen Zhou

Drug-drug interaction prediction is a crucial issue in molecular biology. Traditional methods of observing drug-drug interactions through medical experiments require significant resources and labor. This paper presents a medical knowledge…

Computation and Language · Computer Science 2024-07-29 Peng Gao , Feng Gao , Jian-Cheng Ni , Yu Wang , Fei Wang

Users typically engage with LLMs interactively, yet most existing benchmarks evaluate them in a static, single-turn format, posing reliability concerns in interactive scenarios. We identify a key obstacle towards reliability: LLMs are…

Computation and Language · Computer Science 2024-11-08 Shuyue Stella Li , Vidhisha Balachandran , Shangbin Feng , Jonathan S. Ilgen , Emma Pierson , Pang Wei Koh , Yulia Tsvetkov

Recent advances in multimodal question answering have primarily focused on combining heterogeneous modalities or fine-tuning multimodal large language models. While these approaches have shown strong performance, they often rely on a…

Computation and Language · Computer Science 2026-04-22 Krishna Singh Rajput , Tejas Anvekar , Chitta Baral , Vivek Gupta

We focus on a conversational question answering task which combines the challenges of understanding questions in context and reasoning over evidence gathered from heterogeneous sources like text, knowledge graphs, tables, and infoboxes. Our…

Computation and Language · Computer Science 2024-07-16 Parag Jain , Mirella Lapata

Clinicians are increasingly looking towards machine learning to gain insights about patient evolutions. We propose a novel approach named Multi-Modal UMLS Graph Learning (MMUGL) for learning meaningful representations of medical concepts…

Machine Learning · Computer Science 2024-02-07 Manuel Burger , Gunnar Rätsch , Rita Kuznetsova

Multi-modal learning has significantly advanced generative AI, especially in vision-language modeling. Innovations like GPT-4V and open-source projects such as LLaVA have enabled robust conversational agents capable of zero-shot task…

Computation and Language · Computer Science 2024-06-17 Zekai Chen , Arda Pekis , Kevin Brown

Large Language Models (LLMs) have the potential of facilitating the development of Artificial Intelligence technology to assist medical experts for interactive decision support, which has been demonstrated by their competitive performances…

Computation and Language · Computer Science 2024-11-12 Iñigo Alonso , Maite Oronoz , Rodrigo Agerri

Recently, both closed-source LLMs and open-source communities have made significant strides, outperforming humans in various general domains. However, their performance in specific professional fields such as medicine, especially within the…

Computation and Language · Computer Science 2024-06-19 Lulu Zhao , Weihao Zeng , Xiaofeng Shi , Hua Zhou , Donglin Hao , Yonghua Lin

Multimodal search-based dialogue is a challenging new task: It extends visually grounded question answering systems into multi-turn conversations with access to an external database. We address this new challenge by learning a neural…

Computation and Language · Computer Science 2018-11-22 Shubham Agarwal , Ondrej Dusek , Ioannis Konstas , Verena Rieser

Knowledge graphs (KGs) are increasingly used to represent biomedical information in structured, interpretable formats. However, existing biomedical KGs often focus narrowly on molecular interactions or adverse events, overlooking the rich…

Artificial Intelligence · Computer Science 2025-10-01 Asmita Sengupta , David Antony Selby , Sebastian Josef Vollmer , Gerrit Großmann

In this paper, we propose a novel system that integrates state-of-the-art, domain-specific large language models with advanced information retrieval techniques to deliver comprehensive and context-aware responses. Our approach facilitates…

Conversational Health Agents (CHAs) are interactive systems that provide healthcare services, such as assistance and diagnosis. Current CHAs, especially those utilizing Large Language Models (LLMs), primarily focus on conversation aspects.…

Computation and Language · Computer Science 2024-09-26 Mahyar Abbasian , Iman Azimi , Amir M. Rahmani , Ramesh Jain

In this paper we introduce ClinQueryAgent, a system for translating natural language population health questions into executable database queries using agents with access to both local and external knowledge bases. Our novel architecture…

Information Retrieval · Computer Science 2026-05-20 Joseph S. Boyle , Anthony Dranfield , Mike O'Neil , Maria Liakata , Alison Q. Smithard

Knowledge graphs and large language models (LLMs) are key tools for biomedical knowledge integration and reasoning, facilitating structured organization of scientific articles and discovery of complex semantic relationships. However,…

Computation and Language · Computer Science 2025-04-01 Yichun Feng , Jiawei Wang , Ruikun He , Lu Zhou , Yixue Li

Great research interests have been attracted to devise AI services that are able to provide mental health support. However, the lack of corpora is a main obstacle to this research, particularly in Chinese language. In this paper, we propose…

Computation and Language · Computer Science 2021-06-04 Hao Sun , Zhenru Lin , Chujie Zheng , Siyang Liu , Minlie Huang
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