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A target composition scheme to optimize the combined proton acceleration regime is presented and verified by two-dimensional particle-in-cell (2D PIC) simulations by using an ultra-intense circularly-polarized (CP) laser pulse irradiating…

Plasma Physics · Physics 2016-02-17 W. P. Yao , B. W. Li , C. Y. Zheng , Z. J. Liu , X. Q. Yan

Historically, the discovery and optimization of doped bulk materials has been predominantly developed through an Edisonian approach. While successful and despite the constant progress in fundamental understanding of detector materials…

Materials Science · Physics 2015-08-25 I. V. Khodyuk , S. A. Messina , T. J. Hayden , E. D. Bourret , G. A. Bizarri

We present a highly efficient molecular dynamics scheme for calculating the concentration depth profile of dopants in ion irradiated materials. The scheme incorporates several methods for reducing the computational overhead, plus a rare…

Computational Physics · Physics 2009-10-31 Keith M. Beardmore , Niels Gronbech-Jensen

We present a highly efficient molecular dynamics scheme for calculating the concentration profile of dopants implanted in group-IV alloy, and III-V zinc blende structure materials. Our program incorporates methods for reducing computational…

Materials Science · Physics 2009-10-31 Keith M. Beardmore , Niels Gronbech-Jensen

Aerosol injectors applied in single-particle diffractive imaging experiments demonstrated their potential in efficiently delivering nanoparticles with high density. Continuous optimization of injector design is crucial for achieving…

Ablation with mixed $2\omega$--$3\omega$ lasers is investigated as a possible drive strategy for balancing drive efficiency and ablative stabilization in direct-drive inertial confinement fusion. One-dimensional radiation-hydrodynamic…

Plasma Physics · Physics 2026-05-27 Guannan Zheng , Tao Tao , Qing Jia , Jun Li , Rui Yan , Jian Zheng

High-quality proton beams generated by laser-plasma interactions are of significant interest for applications ranging from tumor therapy to fast ignition in inertial confinement fusion. However, simultaneously achieving high energy coupling…

Plasma Physics · Physics 2026-03-17 Cheng-Qi Zhang , Yang He , Mamat Ali Bake , Bai-Song Xie

Scientific software is often driven by multiple parameters that affect both accuracy and performance. Since finding the optimal configuration of these parameters is a highly complex task, it extremely common that the software is used…

Computational Engineering, Finance, and Science · Computer Science 2016-08-17 Diego Fabregat-Traver , Ahmed E. Ismail , Paolo Bientinesi

A new adaptive hybrid optimization strategy, entitled squads, is proposed for complex inverse analysis of computationally intensive physical models. The new strategy is designed to be computationally efficient and robust in identification…

Geophysics · Physics 2015-06-03 Velimir V. Vesselinov , Dylan R. Harp

One of the most important and difficult parts of constructing a multidimensional numerical simulation of flame acceleration and deflagration-to-detonation transition (DDT) in a reacting flow is finding a reliable and affordable model of the…

Fluid Dynamics · Physics 2017-09-04 Carolyn R. Kaplan , Alp Ozgen , Elaine S. Oran

Simulating the dynamics of ions near polarizable nanoparticles (NPs) using coarse-grained models is extremely challenging due to the need to solve the Poisson equation at every simulation timestep. Recently, a molecular dynamics (MD) method…

Computational Physics · Physics 2019-11-01 JCS Kadupitiya , Geoffrey C. Fox , Vikram Jadhao

Parameter fitting of data to a proposed equation almost always consider these parameters as independent variables. Here, the method proposed optimizes an arbitrary number of variables by the minimization of a function of a single variable.…

Chemical Physics · Physics 2010-06-15 Christopher G. Jesudason

A pulse shape designer for direct drive inertial confinement fusion has been developed, it aims at high compression of the fusion fuel while keeping hydrodynamics instability within tolerable level. Fast linear analysis on implosion…

Plasma Physics · Physics 2023-02-10 Tao Tao , Guannan Zheng , Qing Jia , Rui Yan , Jian Zheng

This work presents a robust design optimization approach for a char combustion process in a limited-data setting, where simulations of the fluid-solid coupled system are computationally expensive. We integrate a polynomial dimensional…

Optimization and Control · Mathematics 2025-03-11 Yulin Guo , Dongjin Lee , Boris Kramer

This paper describes a technique for identifying trends in performance degradation for inertial confinement fusion implosion experiments. It is based on reconstruction of the implosion core with a combination of low- and mid-mode…

Inverse problem or parameter estimation of ordinary differential equations (ODEs), the iterative process of minimizing the mismatch between model-predicted and experimental states by tuning the parameter values within an optimization…

Systems and Control · Electrical Eng. & Systems 2026-04-21 Siddharth Prabhu , Srinivas Rangarajan , Mayuresh Kothare

Doping to induce suitable impurity levels is an effective strategy to achieve highly efficient photocatalytic overall water splitting (POWS). However, to predict the position of impurity levels, it is not enough to only depend on the…

Materials Science · Physics 2023-08-24 Dazhong Sun , Wentao Li , Anqi Shi , Wenxia Zhang , Huabing Shu , Fengfeng Chi , Bing Wang , Xiuyun Zhang , Xianghong Niu

For many applications of pulsed radiation, the time-history of the radiation intensity must be optimized to induce a desired time-history of conditions. This optimization is normally performed using multi-physics simulations of the system.…

Computational Physics · Physics 2019-03-14 Damian C. Swift , George B. Zimmerman

Chemotherapy is one of the primary modalities of cancer treatment. Chemotherapy drug administration is a complex problem that often requires expensive clinical trials to evaluate potential regimens. One way to alleviate this burden and…

Optimization and Control · Mathematics 2021-11-04 Temitayo Ajayi , Seyedmohammadhossein Hosseinian , Andrew J. Schaefer , Clifton D. Fuller

The optimization of cooling systems is important in many cases, for example for cabin and battery cooling in electric cars. Such an optimization is governed by multiple, conflicting objectives and it is performed across a multi-dimensional…

Human-Computer Interaction · Computer Science 2025-07-25 Rainer Splechtna , Majid Behravan , Mario Jelovic , Denis Gracanin , Helwig Hauser , Kresimir Matkovic
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