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The replicator equation is ubiquitous for many areas of mathematical biology. One of major shortcomings of this equation is that it does not allow for an explicit spatial structure. Here we review analytical approaches to include spatial…

Populations and Evolution · Quantitative Biology 2011-05-06 Artem S. Novozhilov , Vladimir P. Posvyanskii , Alexander S. Bratus

Fitting models to data is an important part of the practice of science. Advances in machine learning have made it possible to fit more -- and more complex -- models, but have also exacerbated a problem: when multiple models fit the data…

Methodology · Statistics 2025-10-27 Alexandre René , André Longtin

Binary observations are often repeated to improve data quality, creating technical replicates. Several scoring methods are commonly used to infer the actual individual state and obtain a probability for each state. The common practice of…

Methodology · Statistics 2025-01-24 Manuela Royer-Carenzi , Hadrien Lorenzo , Pierre Pudlo

In this work we present a model for computation of random processes in digital computers which solves the problem of periodic sequences and hidden errors produced by correlations. We show that systems with non-invertible non-linearities can…

Statistical Mechanics · Physics 2007-05-23 Monica A. Garcia-Nustes , Leonardo Trujillo , Jorge A. Gonzalez

Metastability is a common obstacle to performing long molecular dynamics simulations. Many numerical methods have been proposed to overcome it. One method is parallel replica dynamics, which relies on the rapid convergence of the underlying…

Numerical Analysis · Mathematics 2015-05-20 Andrew Binder , Tony Lelièvre , Gideon Simpson

This paper is about how we study statistical methods. As an example, it uses the random regressions model, in which the intercept and slope of cluster-specific regression lines are modeled as a bivariate random effect. Maximizing this…

Other Statistics · Statistics 2019-05-22 James S. Hodges

Discrete mixture models are routinely used for density estimation and clustering. While conducting inferences on the cluster-specific parameters, current frequentist and Bayesian methods often encounter problems when clusters are placed too…

Methodology · Statistics 2012-09-21 Francesca Petralia , Vinayak Rao , David B. Dunson

A systematic replica field theory calculations are analysed using the examples of two particular one-dimensional "toy" random models with Gaussian disorder. Due to apparent simplicity of the model the replica trick calculations can be…

Statistical Mechanics · Physics 2010-10-20 Victor Dotsenko

Mixture models are one of the most widely used statistical tools when dealing with data from heterogeneous populations. This paper considers the long-standing debate over finite mixture and infinite mixtures and brings the two modelling…

Methodology · Statistics 2019-04-23 Raffaele Argiento , Maria De Iorio

A reaction--diffusion replicator equation is studied. A novel method to apply the principle of global regulation is used to write down the model with explicit spatial structure. Properties of stationary solutions together with their…

Populations and Evolution · Quantitative Biology 2013-08-28 Artem S. Novozhilov , Vladimir P. Posvyanskii , Alexander S. Bratus

The fluctuations in nonequilibrium systems are under intense theoretical and experimental investigation. Topical ``fluctuation relations'' describe symmetries of the statistical properties of certain observables, in a variety of models and…

Statistical Mechanics · Physics 2011-09-08 Lamberto Rondoni , Carlos Mejia-Monasterio

This manuscript contributes a general and practical framework for casting a Markov process model of a system at equilibrium as a structural causal model, and carrying out counterfactual inference. Markov processes mathematically describe…

Machine Learning · Statistics 2019-11-07 Robert Osazuwa Ness , Kaushal Paneri , Olga Vitek

We develop a method for the evaluation of extreme event statistics associated with nonlinear dynamical systems, using a small number of samples. From an initial dataset of design points, we formulate a sequential strategy that provides the…

Machine Learning · Computer Science 2022-06-08 Mustafa A. Mohamad , Themistoklis P. Sapsis

There is a lot of research on probabilistic transition systems. There are not many studies in probabilistic process models. The lack of investigation into the interactive aspect of probabilistic processes is mainly due to the difficulty…

Logic in Computer Science · Computer Science 2019-06-25 Yuxi Fu

The convergence to equilibrium for renormalised solutions to nonlinear reaction-diffusion systems is studied. The considered reaction-diffusion systems arise from chemical reaction networks with mass action kinetics and satisfy the complex…

Analysis of PDEs · Mathematics 2018-05-09 Klemens Fellner , Bao Q. Tang

System modeling is a classical approach to ensure their reliability since it is suitable both for a formal verification and for software testing techniques. In the context of model-based testing an approach combining random testing and…

Software Engineering · Computer Science 2018-06-14 Julien Bernard , Pierre-Cyrille Héam , Olga Kouchnarenko

Alignment algorithms usually rely on simplified models of gaps for computational efficiency. Based on an isomorphism between alignments and physical helix-coil models, we show in statistical mechanics that alignments with realistic laws for…

Genomics · Quantitative Biology 2015-06-26 E. Yeramian , E. Debonneuil

We describe an approach to improving model fitting and model generalization that considers the entropy of distributions of modelling residuals. We use simple simulations to demonstrate the observational signatures of overfitting on ordered…

Methodology · Statistics 2019-08-05 Barnaby Rowe

We suggest a novel stochastic-approximation algorithm to compute a symmetric Nash-equilibrium strategy in a general queueing game with a finite action space. The algorithm involves a single simulation of the queueing process with dynamic…

Probability · Mathematics 2023-08-30 Liron Ravner , Ran I. Snitkovsky

The paper deals with the problem of output regulation of nonlinear systems by presenting a learning-based adaptive internal model-based design strategy. We borrow from the adaptive internal model design technique recently proposed in [1]…

Systems and Control · Electrical Eng. & Systems 2022-06-27 Lorenzo Gentilini , Michelangelo Bin , Lorenzo Marconi