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We present PPI++: a computationally lightweight methodology for estimation and inference based on a small labeled dataset and a typically much larger dataset of machine-learning predictions. The methods automatically adapt to the quality of…

Machine Learning · Statistics 2024-03-27 Anastasios N. Angelopoulos , John C. Duchi , Tijana Zrnic

Classification is the task of assigning a new instance to one of a set of predefined categories based on the attributes of the instance. A classification tree is one of the most commonly used techniques in the area of classification. In…

Methodology · Statistics 2021-08-26 Abdulmajeed Atiah Alharbi , Frank P. A. Coolen , Tahani Coolen-Maturi

The use of big data in official statistics and the applied sciences is accelerating, but statistics computed using only big data often suffer from substantial selection bias. This leads to inaccurate estimation and invalid statistical…

Methodology · Statistics 2023-08-11 Ryan Covey , Lucca Buonamano

Generalized variational inference (GVI) provides an optimization-theoretic framework for statistical estimation that encapsulates many traditional estimation procedures. The typical GVI problem is to compute a distribution of parameters…

Optimization and Control · Mathematics 2023-10-27 Aurya S. Javeed , Drew P. Kouri , Thomas M. Surowiec

Data-adaptive (machine learning-based) effect estimators are increasingly popular to reduce bias in high-dimensional bioinformatic and clinical studies (e.g. real-world data, target trials, -omic discovery). Their relative statistical…

Methodology · Statistics 2022-06-13 Xiang Meng , Jonathan Huang

This paper considers the problem of design-based inference for the average treatment effect in finely stratified experiments. Here, by "design-based'' we mean that the only source of uncertainty stems from the randomness in treatment…

Econometrics · Economics 2025-05-08 Yuehao Bai , Xun Huang , Joseph P. Romano , Azeem M. Shaikh , Max Tabord-Meehan

Accurate conditional prediction in the regression setting plays an important role in many real-world problems. Typically, a point prediction often falls short since no attempt is made to quantify the prediction accuracy. Classically, under…

Methodology · Statistics 2025-09-04 Kejin Wu , Dimitris N. Politis

The Gini score is a popular tool in statistical modeling and machine learning for model validation and model selection. It is a purely rank based score that allows one to assess risk rankings. The Gini score for statistical modeling has…

Machine Learning · Statistics 2025-11-20 Alexej Brauer , Mario V. Wüthrich

Uncertainty quantification is critical in scientific inverse problems to distinguish identifiable parameters from those that remain ambiguous given available measurements. The Conditional Diffusion Model-based Inverse Problem Solver (CDI)…

Machine Learning · Computer Science 2026-01-27 Dmitrii Torbunov , Yihui Ren , Lijun Wu , Yimei Zhu

We consider problems of parameter estimation where design variables can be actively optimized to maximize information gain. To this end, we introduce JADAI, a framework that jointly amortizes Bayesian adaptive design and inference by…

Evaluation of treatment effects and more general estimands is typically achieved via parametric modelling, which is unsatisfactory since model misspecification is likely. Data-adaptive model building (e.g. statistical/machine learning) is…

Statistics Theory · Mathematics 2022-01-14 Oliver Hines , Oliver Dukes , Karla Diaz-Ordaz , Stijn Vansteelandt

Physics-informed neural networks (PINNs) are one popular approach to incorporate a priori knowledge about physical systems into the learning framework. PINNs are known to be robust for smaller training sets, derive better generalization…

Machine Learning · Computer Science 2024-06-19 Birgit Hillebrecht , Benjamin Unger

By recasting indirect inference estimation as a prediction rather than a minimization and by using regularized regressions, we can bypass the three major problems of estimation: selecting the summary statistics, defining the distance…

Econometrics · Economics 2020-02-04 Ernesto Carrella , Richard M. Bailey , Jens Koed Madsen

In classification tasks, the long-tailed minority classes usually offer the predictions that are most important. Yet these classes consistently exhibit low accuracies, whereas a few high-performing classes dominate the game. We pursue a…

Machine Learning · Computer Science 2026-03-18 Ruixi Lin

Currently, the high-precision estimation of nonlinear parameters such as Gini indices, low-income proportions or other measures of inequality is particularly crucial. In the present paper, we propose a general class of estimators for such…

Methodology · Statistics 2014-07-01 Camelia Goga , Anne Ruiz-Gazen

Indirect Inference (I-I) is a popular technique for estimating complex parametric models whose likelihood function is intractable, however, the statistical efficiency of I-I estimation is questionable. While the efficient method of moments,…

Econometrics · Economics 2020-06-19 Veronika Czellar , David T. Frazier , Eric Renault

Unbinned likelihood fits aim at maximizing the information one can extract from experimental data, yet their application in realistic statistical analyses is often hindered by the computational cost of profiling systematic uncertainties.…

High Energy Physics - Phenomenology · Physics 2026-02-16 Davide Valsecchi , Mauro Donegà , Rainer Wallny

Deep neural networks exhibit remarkable performance, yet their black-box nature limits their utility in fields like healthcare where interpretability is crucial. Existing explainability approaches often sacrifice accuracy and lack…

Machine Learning · Computer Science 2025-04-08 Linhui Huang , Sayeri Lala , Niraj K. Jha

This paper analyzes several different biases that emerge from the (possibly) low-precision nonparametric ingredient in a semiparametric model. We show that both the variance part and the bias part of the nonparametric ingredient can lead to…

Statistics Theory · Mathematics 2020-10-15 Jungjun Choi , Xiye Yang

We consider the problem of precision matrix estimation where, due to extraneous confounding of the underlying precision matrix, the data are independent but not identically distributed. While such confounding occurs in many scientific…

Machine Learning · Statistics 2019-07-01 Sinong Geng , Mladen Kolar , Oluwasanmi Koyejo