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Related papers: In-BoXBART: Get Instructions into Biomedical Multi…

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To enhance the performance of large language models (LLMs) in biomedical natural language processing (BioNLP) by introducing a domain-specific instruction dataset and examining its impact when combined with multi-task learning principles.…

Computation and Language · Computer Science 2024-06-10 Hieu Tran , Zhichao Yang , Zonghai Yao , Hong Yu

Large Language Models (LLMs) are expected to significantly contribute to patient care, diagnostics, and administrative processes. Emerging biomedical LLMs aim to address healthcare-specific challenges, including privacy demands and…

Computation and Language · Computer Science 2025-10-14 Amin Dada , Marie Bauer , Amanda Butler Contreras , Osman Alperen Koraş , Constantin Marc Seibold , Kaleb E Smith , Jens Kleesiek

Large Language Models (LLMs), particularly those similar to ChatGPT, have significantly influenced the field of Natural Language Processing (NLP). While these models excel in general language tasks, their performance in domain-specific…

Computation and Language · Computer Science 2024-01-02 Omid Rohanian , Mohammadmahdi Nouriborji , David A. Clifton

Large language models (LLMs) such as ChatGPT are fine-tuned on large and diverse instruction-following corpora, and can generalize to new tasks. However, those instruction-tuned LLMs often perform poorly in specialized medical natural…

Computation and Language · Computer Science 2025-03-11 Yujuan Velvin Fu , Giridhar Kaushik Ramachandran , Namu Park , Kevin Lybarger , Fei Xia , Ozlem Uzuner , Meliha Yetisgen

Multi-task learning (MTL), instruction tuning, and prompting have recently been shown to improve the generalizability of large language models to new tasks. However, the benefits of such methods are less well-documented in smaller language…

Computation and Language · Computer Science 2022-10-11 Alon Albalak , Akshat Shrivastava , Chinnadhurai Sankar , Adithya Sagar , Mike Ross

Instruction tuning, a new learning paradigm that fine-tunes pre-trained language models on tasks specified through instructions, has shown promising zero-shot performance on various natural language processing tasks. However, it has yet to…

Computation and Language · Computer Science 2023-06-13 Zhiyang Xu , Ying Shen , Lifu Huang

Large language models (LLMs) are typically prompted to follow a single instruction per inference call. In this work, we analyze whether LLMs also hold the capability to handle multiple instructions simultaneously, denoted as Multi-Task…

Computation and Language · Computer Science 2024-06-07 Guijin Son , Sangwon Baek , Sangdae Nam , Ilgyun Jeong , Seungone Kim

Large language models (LLMs) have become important tools in solving biological problems, offering improvements in accuracy and adaptability over conventional methods. Several benchmarks have been proposed to evaluate the performance of…

Foundational models, pretrained on a large scale, have demonstrated substantial success across non-medical domains. However, training these models typically requires large, comprehensive datasets, which contrasts with the smaller and more…

Computer Vision and Pattern Recognition · Computer Science 2023-11-17 Raphael Schäfer , Till Nicke , Henning Höfener , Annkristin Lange , Dorit Merhof , Friedrich Feuerhake , Volkmar Schulz , Johannes Lotz , Fabian Kiessling

Recently, Language Models (LMs) instruction-tuned on multiple tasks, also known as multitask-prompted fine-tuning (MT), have shown the capability to generalize to unseen tasks. Previous work has shown that scaling the number of training…

Computation and Language · Computer Science 2023-02-10 Joel Jang , Seungone Kim , Seonghyeon Ye , Doyoung Kim , Lajanugen Logeswaran , Moontae Lee , Kyungjae Lee , Minjoon Seo

The integration of large language model (LLM) techniques in the field of medical analysis has brought about significant advancements, yet the scarcity of large, diverse, and well-annotated datasets remains a major challenge. Medical data…

Computation and Language · Computer Science 2024-10-18 Wenhan Han , Meng Fang , Zihan Zhang , Yu Yin , Zirui Song , Ling Chen , Mykola Pechenizkiy , Qingyu Chen

In multi-task learning, difficulty levels of different tasks are varying. There are many works to handle this situation and we classify them into five categories, including the direct sum approach, the weighted sum approach, the maximum…

Machine Learning · Computer Science 2020-02-13 Sicong Liang , Yu Zhang

Multi-task learning (MTL) has achieved remarkable success in natural language processing applications. In this work, we study a multi-task learning model with multiple decoders on varieties of biomedical and clinical natural language…

Computation and Language · Computer Science 2020-05-07 Yifan Peng , Qingyu Chen , Zhiyong Lu

Large language models (LLMs) have shown great potential in medical question answering (MedQA), yet adapting them to biomedical reasoning remains challenging due to domain-specific complexity and limited supervision. In this work, we study…

Computation and Language · Computer Science 2025-11-12 Chenqian Le , Ziheng Gong , Chihang Wang , Haowei Ni , Panfeng Li , Xupeng Chen

Instruction tuning (IT) achieves impressive zero-shot generalization results by training large language models (LLMs) on a massive amount of diverse tasks with instructions. However, how to select new tasks to improve the performance and…

Computation and Language · Computer Science 2023-11-02 Po-Nien Kung , Fan Yin , Di Wu , Kai-Wei Chang , Nanyun Peng

Large language models are able to perform a task by conditioning on a few input-output demonstrations - a paradigm known as in-context learning. We show that language models can explicitly infer an underlying task from a few demonstrations…

Computation and Language · Computer Science 2022-05-24 Or Honovich , Uri Shaham , Samuel R. Bowman , Omer Levy

Recent work has shown that language models (LMs) trained with multi-task \textit{instructional learning} (MTIL) can solve diverse NLP tasks in zero- and few-shot settings with improved performance compared to prompt tuning. MTIL illustrates…

Computation and Language · Computer Science 2022-10-24 Budhaditya Deb , Guoqing Zheng , Ahmed Hassan Awadallah

Predicting multiple heterogeneous biological and medical targets is a challenge for traditional deep learning models. In contrast to single-task learning, in which a separate model is trained for each target, multi-task learning (MTL)…

Machine Learning · Computer Science 2022-05-31 Raquel Aoki , Frederick Tung , Gabriel L. Oliveira

Large Language Models (LLMs), with their remarkable task-handling capabilities and innovative outputs, have catalyzed significant advancements across a spectrum of fields. However, their proficiency within specialized domains such as…

Quantitative Methods · Quantitative Biology 2024-03-05 Yin Fang , Xiaozhuan Liang , Ningyu Zhang , Kangwei Liu , Rui Huang , Zhuo Chen , Xiaohui Fan , Huajun Chen

Recent work has shown that fine-tuning large pre-trained language models on a collection of tasks described via instructions, a.k.a. instruction-tuning, improves their zero and few-shot generalization to unseen tasks. However, there is a…

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