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Markov models of character substitution on phylogenies form the foundation of phylogenetic inference frameworks. Early models made the simplifying assumption that the substitution process is homogeneous over time and across sites in the…

Populations and Evolution · Quantitative Biology 2019-06-13 Guy Baele , Mandev S. Gill , Philippe Lemey , Marc A. Suchard

Multi-species distribution modeling, which relates the occurrence of multiple species to environmental variables, is an important tool used by ecologists for both predicting the distribution of species in a community and identifying the…

Applications · Statistics 2015-09-17 Francis K. C. Hui , David I. Warton , Scott D. Foster

Dynamic networks are a general language for describing time-evolving complex systems, and discrete time network models provide an emerging statistical technique for various applications. It is a fundamental research question to detect the…

Methodology · Statistics 2017-12-21 Kevin H. Lee , Lingzhou Xue , David R. Hunter

Recent strides in interpretable machine learning (ML) research reveal that models exploit undesirable patterns in the data to make predictions, which potentially causes harms in deployment. However, it is unclear how we can fix these…

Cluster-Weighted Modeling (CWM) is a flexible mixture approach for modeling the joint probability of data coming from a heterogeneous population as a weighted sum of the products of marginal distributions and conditional distributions. In…

Methodology · Statistics 2012-12-20 Salvatore Ingrassia , Simona C. Minotti , Antonio Punzo , Giorgio Vittadini

Copulas provide a modular parameterization of multivariate distributions that decouples the modeling of marginals from the dependencies between them. Gaussian Mixture Copula Model (GMCM) is a highly flexible copula that can model many kinds…

Methodology · Statistics 2021-09-29 Siva Rajesh Kasa , Vaibhav Rajan

We introduce a novel class of Bayesian mixtures for normal linear regression models which incorporates a further Gaussian random component for the distribution of the predictor variables. The proposed cluster-weighted model aims to…

Methodology · Statistics 2026-05-26 Panagiotis Papastamoulis , Konstantinos Perrakis

This review provides a systematic overview of methods that combine covariate-based clustering of observational units (patients) with outcome models for clinical studies. We distinguish between informed-cluster models, where the outcome…

The Generalized Additive Model (GAM) is a powerful tool and has been well studied. This model class helps to identify additive regression structure. Via available test procedures one may identify the regression structure even sharper if…

Methodology · Statistics 2020-09-11 Rong Liu , Wolfgang Karl Härdle

We propose a novel approach for modeling multivariate longitudinal data in the presence of unobserved heterogeneity for the analysis of the Health and Retirement Study (HRS) data. Our proposal can be cast within the framework of linear…

Methodology · Statistics 2015-09-17 Laura Anderlucci , Cinzia Viroli

Understanding variable dependence, particularly eliciting their statistical properties given a set of covariates, provides the mathematical foundation in practical operations management such as risk analysis and decision-making given…

Methodology · Statistics 2023-09-06 Yunyun Wang , Tatsushi Oka , Dan Zhu

Conditional copulas are flexible statistical tools that couple joint conditional and marginal conditional distributions. In a linear regression setting with more than one covariate and two dependent outcomes, we propose the use of additive…

Methodology · Statistics 2014-07-31 Avideh Sabeti , Mian Wei , Radu V. Craiu

Two of the principle tasks of causal inference are to define and estimate the effect of a treatment on an outcome of interest. Formally, such treatment effects are defined as a possibly functional summary of the data generating…

Statistics Theory · Mathematics 2023-01-26 Herbert Susmann , Antoine Chambaz

Biclustering is used for simultaneous clustering of the observations and variables when there is no group structure known \textit{a priori}. It is being increasingly used in bioinformatics, text analytics, etc. Previously, biclustering has…

Methodology · Statistics 2020-09-14 Wangshu Tu , Sanjeena Subedi

Finite mixture distributions arise in sampling a heterogeneous population. Data drawn from such a population will exhibit extra variability relative to any single subpopulation. Statistical models based on finite mixtures can assist in the…

Methodology · Statistics 2024-01-19 Andrew M. Raim , Nagaraj K. Neerchal , Jorge G. Morel

Integrating various data modalities brings valuable insights into underlying phenomena. Multimodal factor analysis (FA) uncovers shared axes of variation underlying different simple data modalities, where each sample is represented by a…

Machine Learning · Computer Science 2025-04-29 Małgorzata Łazęcka , Ewa Szczurek

In this article, a copula-based method for mixed regression models is proposed, where the conditional distribution of the response variable, given covariates, is modelled by a parametric family of continuous or discrete distributions, and…

Methodology · Statistics 2025-01-13 Pavel Krupskii , Bouchra R Nasri , Bruno N Remillard

Attrition is a common occurrence in cluster randomised trials (CRTs) which leads to missing outcome data. Two approaches for analysing such trials are cluster-level analysis and individual-level analysis. This paper compares the performance…

Methodology · Statistics 2016-03-15 Anower Hossain , Karla Diaz-Ordaz , Jonathan W. Bartlett

Joint models of longitudinal and survival data have become an important tool for modeling associations between longitudinal biomarkers and event processes. The association between marker and log-hazard is assumed to be linear in existing…

Methodology · Statistics 2017-10-24 Meike Köhler , Nikolaus Umlauf , Sonja Greven

Linear regression is a frequently used tool in statistics, however, its validity and interpretability relies on strong model assumptions. While robust estimates of the coefficients' covariance extend the validity of hypothesis tests and…

Methodology · Statistics 2015-04-23 Werner Brannath , Martin Scharpenberg