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The latest advances in computer-assisted precision medicine are making it feasible to move from population-wide models that are useful to discover aggregate patterns that hold for group-based analysis to patient-specific models that can…

Thoracic trauma often results in rib fractures, which demand swift and accurate diagnosis for effective treatment. However, detecting these fractures on rib CT scans poses considerable challenges, involving the analysis of many image slices…

Detection of surgical instruments plays a key role in ensuring patient safety in minimally invasive surgery. In this paper, we present a novel method for 2D vision-based recognition and pose estimation of surgical instruments that…

Deep neural networks have become the gold-standard approach for the automated segmentation of 3D medical images. Their full acceptance by clinicians remains however hampered by the lack of intelligible uncertainty assessment of the provided…

Automatic parsing of human anatomies at the instance-level from 3D computed tomography (CT) is a prerequisite step for many clinical applications. The presence of pathologies, broken structures or limited field-of-view (FOV) can all make…

Accurate lumbar spine segmentation is crucial for diagnosing spinal disorders. Existing methods typically use coarse-grained segmentation strategies that lack the fine detail needed for precise diagnosis. Additionally, their reliance on…

Osteoporosis, a major global epidemic, often goes undetected until a fracture occurs, largely due to poor access to screening using gold standard methods, such as dual-energy X-ray absorptiometry (DXA). As a potential nonionizing radiation…

Localization of focal vascular lesions on brain MRI is an important component of research on the etiology of neurological disorders. However, manual annotation of lesions can be challenging, time-consuming and subject to observer bias.…

Accurate identification and localization of the vertebrae in CT scans is a critical and standard preprocessing step for clinical spinal diagnosis and treatment. Existing methods are mainly based on the integration of multiple neural…

Foot ulcer is a common complication of diabetes mellitus and, associated with substantial morbidity and mortality, remains a major risk factor for lower leg amputations. Extracting accurate morphological features from foot wounds is crucial…

Intervertebral discs (IVDs), as small joints lying between adjacent vertebrae, have played an important role in pressure buffering and tissue protection. The fully-automatic localization and segmentation of IVDs have been discussed in the…

In this article, we present a graph-based method using a cubic template for volumetric segmentation of vertebrae in magnetic resonance imaging (MRI) acquisitions. The user can define the degree of deviation from a regular cube via a…

Radiotherapy-induced normal tissue injury is a clinically important complication, and accurate segmentation of injury regions from medical images could facilitate disease assessment, treatment planning, and longitudinal monitoring. However,…

Cortical lesions (CLs) have emerged as valuable biomarkers in multiple sclerosis (MS), offering high diagnostic specificity and prognostic relevance. However, their routine clinical integration remains limited due to subtle magnetic…

Bone fractures present a major global health challenge, often resulting in pain, reduced mobility, and productivity loss, particularly in low-resource settings where access to expert radiology services is limited. Conventional imaging…

The following paper proposes two contour-based fracture detection schemes. The development of the contour-based fracture is based on the line-based fracture detection schemes proposed in arXiv:1902.07458. Existing Computer Aided Diagnosis…

This paper introduces a novel method for characterizing fracture mechanisms in composite materials using 3D image data gained by computed tomography (CT) measurements. In mineral liberation, the understanding of these mechanisms is crucial,…

The relationship between knee osteoarthritis progression and changes in tibial bone structure has long been recognized and various texture descriptors have been proposed to detect early osteoarthritis (OA) from radiographs. This work aims…

Tissue stiffness is related to soft tissue pathologies and can be assessed through palpation or via clinical imaging systems, e.g., ultrasound or magnetic resonance imaging. Typically, the image based approaches are not suitable during…

Purpose: Proximal femur image analyses based on quantitative computed tomography (QCT) provide a method to quantify the bone density and evaluate osteoporosis and risk of fracture. We aim to develop a deep-learning-based method for…