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Accurate prediction of clinical outcomes using Electronic Health Records (EHRs) is critical for early intervention, efficient resource allocation, and improved patient care. EHRs contain multimodal data, including both structured data and…

Machine Learning · Computer Science 2025-08-29 Rituparna Datta , Jiaming Cui , Zihan Guan , Vishal G. Reddy , Joshua C. Eby , Gregory Madden , Rupesh Silwal , Anil Vullikanti

Electronic health records (EHR) contain narrative notes that provide extensive details on the medical condition and management of patients. Natural language processing (NLP) of clinical notes can use observed frequencies of clinical terms…

Computation and Language · Computer Science 2023-07-04 Bryan Cai , Sihang Zeng , Yucong Lin , Zheng Yuan , Doudou Zhou , Lu Tian

Accessing longitudinal multimodal Electronic Healthcare Records (EHRs) is challenging due to privacy concerns, which hinders the use of ML for healthcare applications. Synthetic EHRs generation bypasses the need to share sensitive real…

Computation and Language · Computer Science 2022-11-04 Zifeng Wang , Jimeng Sun

Clinical coding is currently a labour-intensive, error-prone, but critical administrative process whereby hospital patient episodes are manually assigned codes by qualified staff from large, standardised taxonomic hierarchies of codes.…

Machine Learning · Computer Science 2023-02-28 Thomas Searle , Zina Ibrahim , Richard JB Dobson

Accurate clinical prognosis requires synthesizing structured Electronic Health Records (EHRs) with real-time physiological signals like the Electrocardiogram (ECG). Large Language Models (LLMs) offer a powerful reasoning engine for this…

Machine Learning · Computer Science 2026-01-27 Jialu Tang , Tong Xia , Yuan Lu , Aaqib Saeed

The shift to electronic medical records (EMRs) has engendered research into machine learning and natural language technologies to analyze patient records, and to predict from these clinical outcomes of interest. Two observations motivate…

Computation and Language · Computer Science 2019-04-09 Sarthak Jain , Ramin Mohammadi , Byron C. Wallace

Difficulty replicating baselines, high computational costs, and required domain expertise create persistent barriers to clinical AI research. To address these challenges, we introduce PyHealth 2.0, an enhanced clinical deep learning toolkit…

Background and Objective: Open-source deep learning toolkits are one of the driving forces for developing medical image segmentation models. Existing toolkits mainly focus on fully supervised segmentation and require full and accurate…

Image and Video Processing · Electrical Eng. & Systems 2023-02-14 Guotai Wang , Xiangde Luo , Ran Gu , Shuojue Yang , Yijie Qu , Shuwei Zhai , Qianfei Zhao , Kang Li , Shaoting Zhang

Background Predicting mortality and resource utilization from electronic health records (EHRs) is challenging yet crucial for optimizing patient outcomes and managing costs in intensive care unit (ICU). Existing approaches predominantly…

Computation and Language · Computer Science 2025-08-29 Yucheng Ruan , Xiang Lan , Daniel J. Tan , Hairil Rizal Abdullah , Mengling Feng

Research projects, including those focused on cancer, rely on the manual extraction of information from clinical reports. This process is time-consuming and prone to errors, limiting the efficiency of data-driven approaches in healthcare.…

Computation and Language · Computer Science 2025-05-16 J. Moreno-Casanova , J. M. Auñón , A. Mártinez-Pérez , M. E. Pérez-Martínez , M. E. Gas-López

Electronic Health Records (EHRs) hold immense potential for advancing healthcare, offering rich, longitudinal data that combines structured information with valuable insights from unstructured clinical notes. However, the unstructured…

Computation and Language · Computer Science 2025-01-31 Huaiyuan Ying , Hongyi Yuan , Jinsen Lu , Zitian Qu , Yang Zhao , Zhengyun Zhao , Isaac Kohane , Tianxi Cai , Sheng Yu

Electronic health record (EHR) data are becoming an increasingly common data source for understanding clinical risk of acute events. While their longitudinal nature presents opportunities to observe changing risk over time, these analyses…

Clinical notes containing valuable patient information are written by different health care providers with various scientific levels and writing styles. It might be helpful for clinicians and researchers to understand what information is…

Computation and Language · Computer Science 2023-03-17 Hoda Memarzadeh , Nasser Ghadiri , Matthias Samwald , Maryam Lotfi Shahreza

Objective: Clinical trials are essential for advancing pharmaceutical interventions, but they face a bottleneck in selecting eligible participants. Although leveraging electronic health records (EHR) for recruitment has gained popularity,…

Computation and Language · Computer Science 2026-01-15 Mojdeh Rahmanian , Seyed Mostafa Fakhrahmad , Seyedeh Zahra Mousavi

Monitoring the health status of patients in the Intensive Care Unit (ICU) is a critical aspect of providing superior care and treatment. The availability of large-scale electronic health records (EHR) provides machine learning models with…

Artificial Intelligence · Computer Science 2023-05-05 Jun Wu , Xuesong Ye , Chengjie Mou , Weinan Dai

Deep learning models exhibit state-of-the-art performance for many predictive healthcare tasks using electronic health records (EHR) data, but these models typically require training data volume that exceeds the capacity of most healthcare…

Machine Learning · Computer Science 2018-10-24 Edward Choi , Cao Xiao , Walter F. Stewart , Jimeng Sun

Real-world clinical text-to-SQL requires reasoning over heterogeneous EHR tables, temporal windows, and patient-similarity cohorts to produce executable queries. We introduce CLINSQL, a benchmark of 633 expert-annotated tasks on MIMIC-IV…

Computation and Language · Computer Science 2026-01-16 Yifei Shen , Yilun Zhao , Justice Ou , Tinglin Huang , Arman Cohan

Recently natural language processing (NLP) tools have been developed to identify and extract salient risk indicators in electronic health records (EHRs). Sentiment analysis, although widely used in non-medical areas for improving decision…

Computation and Language · Computer Science 2019-04-09 Eben Holderness , Philip Cawkwell , Kirsten Bolton , James Pustejovsky , Mei-Hua Hall

The study of historical languages presents unique challenges due to their complex orthographic systems, fragmentary textual evidence, and the absence of standardized digital representations of text in those languages. Tackling these…

Computation and Language · Computer Science 2025-03-25 Farhan Farsi , Parnian Fazel , Sepand Haghighi , Sadra Sabouri , Farzaneh Goshtasb , Nadia Hajipour , Ehsaneddin Asgari , Hossein Sameti

Foundation models trained on patient electronic health records (EHRs) require tokenizing medical data into sequences of discrete vocabulary items. Existing tokenizers treat medical codes from EHRs as isolated textual tokens. However, each…

Computation and Language · Computer Science 2025-07-01 Xiaorui Su , Shvat Messica , Yepeng Huang , Ruth Johnson , Lukas Fesser , Shanghua Gao , Faryad Sahneh , Marinka Zitnik