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Many common estimators in machine learning and causal inference are linear smoothers, where the prediction is a weighted average of the training outcomes. Some estimators, such as ordinary least squares and kernel ridge regression, allow…

Machine Learning · Computer Science 2026-04-02 David Arbour , Harsh Parikh , Bijan Niknam , Elizabeth Stuart , Kara Rudolph , Avi Feller

The computation of the maximum likelihood (ML) estimator for heteroscedastic regression models is considered. The traditional Newton algorithms for the problem require matrix multiplications and inversions, which are bottlenecks in modern…

Computation · Statistics 2016-08-24 Hien D. Nguyen , Luke R. Lloyd-Jones , Geoffrey J. McLachlan

Quantifying uncertainty in deep regression models is important both for understanding the confidence of the model and for safe decision-making in high-risk domains. Existing approaches that yield prediction intervals overlook distributional…

Machine Learning · Computer Science 2025-12-02 Adriel Sosa Marco , John Daniel Kirwan , Alexia Toumpa , Simos Gerasimou

Throughout the life sciences we routinely seek to interpret measurements and observations using parameterised mechanistic mathematical models. A fundamental and often overlooked choice in this approach involves relating the solution of a…

Quantitative Methods · Quantitative Biology 2023-11-10 Ryan J. Murphy , Oliver J. Maclaren , Matthew J. Simpson

The problem of fitting experimental data to a given model function $f(t; p_1,p_2,\dots,p_N)$ is conventionally solved numerically by methods such as that of Levenberg-Marquardt, which are based on approximating the Chi-squared measure of…

Optimization and Control · Mathematics 2017-03-14 Alberto Herrera-Gomez , R. Michael Porter

Regularization in fitting regression models has been a highly active topic of research in the past few decades, but most of the existing methods are designed for particular situations, e.g. for the case of a sparse coefficient vector. We…

Methodology · Statistics 2025-05-15 Asaf Weinstein , Jonas Wallin , Daniel Yekutieli , Małgorzata Bogdan

We propose algorithms for addressing the bias of the posterior mean when used as an estimator of parameters. These algorithms build upon the recently proposed Bayesian infinitesimal jackknife approximation (Giordano and Broderick (2023))…

Methodology · Statistics 2024-09-06 Yukito Iba

In this paper we revisit one of the classical statistical problems, the so-called sparse maximum-likelihood (ML) linear regression. As a way of attacking this type of regression, we present a novel CLuP mechanism that to a degree relies on…

Information Theory · Computer Science 2020-11-24 Mihailo Stojnic

The two primary approaches for high-dimensional regression problems are sparse methods (e.g., best subset selection, which uses the L0-norm in the penalty) and ensemble methods (e.g., random forests). Although sparse methods typically yield…

Methodology · Statistics 2024-10-31 Anthony-Alexander Christidis , Stefan Van Aelst , Ruben Zamar

We consider a model for logistic regression where only a subset of features of size $p$ is used for training a linear classifier over $n$ training samples. The classifier is obtained by running gradient descent (GD) on logistic loss. For…

Machine Learning · Statistics 2020-05-12 Zeyu Deng , Abla Kammoun , Christos Thrampoulidis

The effort to understand network systems in increasing detail has resulted in a diversity of methods designed to extract their large-scale structure from data. Unfortunately, many of these methods yield diverging descriptions of the same…

Data Analysis, Statistics and Probability · Physics 2015-03-27 Tiago P. Peixoto

We introduce a novel approach called the Bayesian Jackknife empirical likelihood method for analyzing survey data obtained from various unequal probability sampling designs. This method is particularly applicable to parameters described by…

Methodology · Statistics 2023-09-14 Mengdong Shang , Xia Chen

Combining matching and regression for causal inference provides double-robustness in removing treatment effect estimation bias due to confounding variables. In most real-world applications, however, treatment and control populations are not…

Methodology · Statistics 2015-07-14 Alireza S. Mahani , Mansour T. A. Sharabiani

Prediction intervals in supervised Machine Learning bound the region where the true outputs of new samples may fall. They are necessary in the task of separating reliable predictions of a trained model from near random guesses, minimizing…

Machine Learning · Computer Science 2019-12-20 Anton Akusok , Yoan Miche , Kaj-Mikael Björk , Amaury Lendasse

Outliers widely occur in big-data applications and may severely affect statistical estimation and inference. In this paper, a framework of outlier-resistant estimation is introduced to robustify an arbitrarily given loss function. It has a…

Methodology · Statistics 2023-04-20 Yiyuan She , Zhifeng Wang , Jiahui Shen

Large language models are typically aligned with human preferences by optimizing $\textit{reward models}$ (RMs) fitted to human feedback. However, human preferences are multi-faceted, and it is increasingly common to derive reward from a…

In system identification, estimating parameters of a model using limited observations results in poor identifiability. To cope with this issue, we propose a new method to simultaneously select and estimate sensitive parameters as key model…

Generalized linear models (GLMs) are fundamental tools for statistical modeling, with maximum likelihood estimation (MLE) serving as the classical approach for parameter inference. While MLE performs well for canonical GLMs, it can become…

Methodology · Statistics 2026-03-03 Linglingzhi Zhu , Jonghyeok Lee , Yao Xie

Downsampling or under-sampling is a technique that is utilized in the context of large and highly imbalanced classification models. We study optimal downsampling for imbalanced classification using generalized linear models (GLMs). We…

Machine Learning · Statistics 2025-05-20 Yan Chen , Jose Blanchet , Krzysztof Dembczynski , Laura Fee Nern , Aaron Flores

This paper develops an approach to inference in a linear regression model when the number of potential explanatory variables is larger than the sample size. The approach treats each regression coefficient in turn as the interest parameter,…

Methodology · Statistics 2022-11-14 Heather S. Battey , Nancy Reid
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