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One of the largest problems in medical image processing is the lack of annotated data. Labeling medical images often requires highly trained experts and can be a time-consuming process. In this paper, we evaluate a method of reducing the…

Computer Vision and Pattern Recognition · Computer Science 2022-06-02 Marin Benčević , Marija Habijan , Irena Galić , Aleksandra Pizurica

Unsupervised Anomaly Detection (UAD) aims to identify abnormal regions by establishing correspondences between test images and normal templates. Existing methods primarily rely on image reconstruction or template retrieval but face a…

Computer Vision and Pattern Recognition · Computer Science 2026-02-24 Mingxiu Cai , Zhe Zhang , Gaochang Wu , Tianyou Chai , Xiatian Zhu

Unsupervised anomaly detection in brain images is crucial for identifying injuries and pathologies without access to labels. However, the accurate localization of anomalies in medical images remains challenging due to the inherent…

Computer Vision and Pattern Recognition · Computer Science 2025-07-25 Farzad Beizaee , Gregory Lodygensky , Christian Desrosiers , Jose Dolz

Machine learning (ML) algorithms are optimized for the distribution represented by the training data. For outlier data, they often deliver predictions with equal confidence, even though these should not be trusted. In order to deploy…

Image and Video Processing · Electrical Eng. & Systems 2021-03-17 Milda Pocevičiūtė , Gabriel Eilertsen , Claes Lundström

To develop a domain-agnostic, semi-supervised anomaly detection framework that integrates deep reinforcement learning (DRL) to address challenges such as large-scale data, overfitting, and class imbalance, focusing on brain MRI volumes.…

Computer Vision and Pattern Recognition · Computer Science 2025-08-05 Zeduo Zhang , Yalda Mohsenzadeh

Collecting large-scale datasets is crucial for training deep models, annotating the data, however, inevitably yields noisy labels, which poses challenges to deep learning algorithms. Previous efforts tend to mitigate this problem via…

Computer Vision and Pattern Recognition · Computer Science 2023-02-16 Yuanpeng Tu , Boshen Zhang , Yuxi Li , Liang Liu , Jian Li , Jiangning Zhang , Yabiao Wang , Chengjie Wang , Cai Rong Zhao

We propose a supervised anomaly detection method based on neural density estimators, where the negative log likelihood is used for the anomaly score. Density estimators have been widely used for unsupervised anomaly detection. By the recent…

Machine Learning · Statistics 2019-04-15 Tomoharu Iwata , Yuki Yamanaka

In this study, a new Anomaly Detection (AD) approach for industrial and medical images is proposed. This method leverages the theoretical strengths of unsupervised learning and the data availability of both normal and abnormal classes.…

Computer Vision and Pattern Recognition · Computer Science 2024-01-24 Arnaud Bougaham , Valentin Delchevalerie , Mohammed El Adoui , Benoît Frénay

Deep learning models in medical imaging often encounter challenges when adapting to new clinical settings unseen during training. Test-time adaptation offers a promising approach to optimize models for these unseen domains, yet its…

Machine Learning · Computer Science 2024-10-28 Sameer Ambekar , Julia A. Schnabel , Cosmin I. Bercea

Deep neural networks (DNN) can achieve high performance when applied to In-Distribution (ID) data which come from the same distribution as the training set. When presented with anomaly inputs not from the ID, the outputs of a DNN should be…

Machine Learning · Computer Science 2021-10-08 Fangzhen Zhao , Chenyi Zhang , Naipeng Dong , Zefeng You , Zhenxin Wu

Deep learning models trained on medical images from a source domain (e.g. imaging modality) often fail when deployed on images from a different target domain, despite imaging common anatomical structures. Deep unsupervised domain adaptation…

Image and Video Processing · Electrical Eng. & Systems 2019-08-14 Cheng Ouyang , Konstantinos Kamnitsas , Carlo Biffi , Jinming Duan , Daniel Rueckert

Anomaly detection (AD) plays a pivotal role in multimedia applications for detecting defective products and automating quality inspection. Deep learning (DL) models typically require large-scale annotated data, which are often highly…

Computer Vision and Pattern Recognition · Computer Science 2024-10-22 Eirini Cholopoulou , Dimitris K. Iakovidis

In medical imaging, anomaly detection is a vital element of healthcare diagnostics, especially for neurological conditions which can be life-threatening. Conventional deterministic methods often fall short when it comes to capturing the…

Machine Learning · Computer Science 2025-04-23 Dip Roy

Computer-aided diagnosis for low-dose computed tomography (CT) based on deep learning has recently attracted attention as a first-line automatic testing tool because of its high accuracy and low radiation exposure. However, existing methods…

Image and Video Processing · Electrical Eng. & Systems 2022-06-28 Kyung-Su Kim , Seong Je Oh , Ju Hwan Lee , Myung Jin Chung

The amount of manually labeled data is limited in medical applications, so semi-supervised learning and automatic labeling strategies can be an asset for training deep neural networks. However, the quality of the automatically generated…

Machine Learning · Computer Science 2022-03-04 Wenhui Cui , Haleh Akrami , Anand A. Joshi , Richard M. Leahy

Although mainstream unsupervised anomaly detection (AD) (including image-level classification and pixel-level segmentation)algorithms perform well in academic datasets, their performance is limited in practical application due to the ideal…

Computer Vision and Pattern Recognition · Computer Science 2025-01-14 Chengjie Wang , Xi Jiang , Bin-Bin Gao , Zhenye Gan , Yong Liu , Feng Zheng , Lizhuang Ma

Supervised deep learning algorithms have enabled significant performance gains in medical image classification tasks. But these methods rely on large labeled datasets that require resource-intensive expert annotation. Semi-supervised…

The remarkable success of today's deep neural networks highly depends on a massive number of correctly labeled data. However, it is rather costly to obtain high-quality human-labeled data, leading to the active research area of training…

Machine Learning · Computer Science 2020-11-04 Jiacheng Wang , Yue Ma , Shuang Gao

Deep learning techniques have led to state-of-the-art image super resolution with natural images. Normally, pairs of high-resolution and low-resolution images are used to train the deep learning models. These techniques have also been…

Image and Video Processing · Electrical Eng. & Systems 2022-10-14 Yutaro Iwamoto , Kyohei Takeda , Yinhao Li , Akihiko Shiino , Yen-Wei Chen

State-of-the-art, high capacity deep neural networks not only require large amounts of labelled training data, they are also highly susceptible to label errors in this data, typically resulting in large efforts and costs and therefore…

Machine Learning · Computer Science 2020-07-20 Christian Haase-Schütz , Rainer Stal , Heinz Hertlein , Bernhard Sick