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Magnetic Resonance Imaging (MRI) is the primary imaging modality used in the diagnosis, assessment, and treatment planning for brain pathologies. However, most automated MRI analysis tools, such as segmentation and registration pipelines,…

Deep learning-based models in medical imaging often struggle to generalize effectively to new scans due to data heterogeneity arising from differences in hardware, acquisition parameters, population, and artifacts. This limitation presents…

Image and Video Processing · Electrical Eng. & Systems 2023-08-09 Sebastian Nørgaard Llambias , Mads Nielsen , Mostafa Mehdipour Ghazi

Head MRI pre-processing involves converting raw images to an intensity-normalized, skull-stripped brain in a standard coordinate space. In this paper, we propose an end-to-end weakly supervised learning approach, called Neural…

Image and Video Processing · Electrical Eng. & Systems 2023-03-23 Xinzi He , Alan Wang , Mert R. Sabuncu

Lack of standardization and various intrinsic parameters for magnetic resonance (MR) image acquisition results in heterogeneous images across different sites and devices, which adversely affects the generalization of deep neural networks.…

Deep learning has achieved remarkable success in medical image analysis, yet its performance remains highly sensitive to the heterogeneity of clinical data. Differences in imaging hardware, staining protocols, and acquisition conditions…

Image and Video Processing · Electrical Eng. & Systems 2026-03-18 Callen MacPhee , Yiming Zhou , Koichiro Kishima , Bahram Jalali

Image Quality of MRI brain scans is strongly influenced by within scanner head movements and the resulting image artifacts alter derived measures like brain volume and cortical thickness. Automated image quality assessment is key to…

Image and Video Processing · Electrical Eng. & Systems 2024-11-05 Felix Hoffstaedter , Nicolás Nieto , Simon B. Eickhoff , Kaustubh R. Patil

Automatic segmentation of brain tumors in intra-operative ultrasound (iUS) images could facilitate localization of tumor tissue during resection surgery. The lack of large annotated datasets limits the current models performances. In this…

Image and Video Processing · Electrical Eng. & Systems 2025-08-18 Mathilde Faanes , Ragnhild Holden Helland , Ole Solheim , Sébastien Muller , Ingerid Reinertsen

Accurate and reproducible brain morphometry from structural MRI is critical for monitoring neuroanatomical changes across time and across imaging domains. Although deep learning has accelerated segmentation workflows, scanner-induced…

Computer Vision and Pattern Recognition · Computer Science 2025-04-23 Ekaterina Kondrateva , Sandzhi Barg , Mikhail Vasiliev

Large-scale brain imaging datasets provide unprecedented opportunities for developing domain foundation models through pretraining. However, unlike natural image datasets in computer vision, these neuroimaging data often exhibit high…

Computer Vision and Pattern Recognition · Computer Science 2025-12-19 Yanteng Zhang , Songheng Li , Zeyu Shen , Qizhen Lan , Lipei Zhang , Yang Liu , Vince Calhoun

Medical image analysis using deep neural networks has been actively studied. Deep neural networks are trained by learning data. For accurate training of deep neural networks, the learning data should be sufficient, of good quality, and…

Image and Video Processing · Electrical Eng. & Systems 2021-01-05 Sunho Kim , Byungjai Kim , HyunWook Park

The complex heterogeneity of brain tumours is increasingly recognized to demand data of magnitudes and richness only fully-inclusive, large-scale collections drawn from routine clinical care could plausibly offer. This is a task…

Computer Vision and Pattern Recognition · Computer Science 2023-05-01 James K Ruffle , Samia Mohinta , Robert J Gray , Harpreet Hyare , Parashkev Nachev

Magnetic Resonance Imaging (MRI) is the most commonly used non-intrusive technique for medical image acquisition. Brain tumor segmentation is the process of algorithmically identifying tumors in brain MRI scans. While many approaches have…

Image and Video Processing · Electrical Eng. & Systems 2022-11-04 Jason Walsh , Alice Othmani , Mayank Jain , Soumyabrata Dev

A brain tumor, whether benign or malignant, can potentially be life threatening and requires painstaking efforts in order to identify the type, origin and location, let alone cure one. Manual segmentation by medical specialists can be…

Image and Video Processing · Electrical Eng. & Systems 2023-05-02 Ayan Gupta , Mayank Dixit , Vipul Kumar Mishra , Attulya Singh , Atul Dayal

Tumor segmentation from multi-modal brain MRI images is a challenging task due to the limited samples, high variance in shapes and uneven distribution of tumor morphology. The performance of automated medical image segmentation has been…

Image and Video Processing · Electrical Eng. & Systems 2024-02-13 Tianyi Ren , Ethan Honey , Harshitha Rebala , Abhishek Sharma , Agamdeep Chopra , Mehmet Kurt

Most of the current state-of-the-art methods for tumor segmentation are based on machine learning models trained on manually segmented images. This type of training data is particularly costly, as manual delineation of tumors is not only…

Computer Vision and Pattern Recognition · Computer Science 2019-08-21 Pawel Mlynarski , Hervé Delingette , Antonio Criminisi , Nicholas Ayache

Despite the large amount of brain CT data generated in clinical practice, the availability of CT datasets for deep learning (DL) research is currently limited. Furthermore, the data can be insufficiently or improperly prepared for machine…

Image and Video Processing · Electrical Eng. & Systems 2023-09-27 Alessandro Fontanella , Wenwen Li , Grant Mair , Antreas Antoniou , Eleanor Platt , Chloe Martin , Paul Armitage , Emanuele Trucco , Joanna Wardlaw , Amos Storkey

In real-world clinical practice, overlooking unanticipated findings can result in serious consequences. However, supervised learning, which is the foundation for the current success of deep learning, only encourages models to identify…

We explore three representative lines of research and demonstrate the utility of our methods on a classification benchmark of brain cancer MRI data. First, we present a capsule network that explicitly learns a representation robust to…

Image and Video Processing · Electrical Eng. & Systems 2020-05-13 Neil Getty , Thomas Brettin , Dong Jin , Rick Stevens , Fangfang Xia

Existing image segmentation networks mainly leverage large-scale labeled datasets to attain high accuracy. However, labeling medical images is very expensive since it requires sophisticated expert knowledge. Thus, it is more desirable to…

Image and Video Processing · Electrical Eng. & Systems 2021-02-04 Yuhang Ding , Xin Yu , Yi Yang

Purpose: The segmentation of brain tumors is one of the most active areas of medical image analysis. While current methods perform superhuman on benchmark data sets, their applicability in daily clinical practice has not been evaluated. In…

Image and Video Processing · Electrical Eng. & Systems 2020-12-17 Sabine Müller , Joachim Weickert , Norbert Graf