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Although the existing uncertainty-based semi-supervised medical segmentation methods have achieved excellent performance, they usually only consider a single uncertainty evaluation, which often fails to solve the problem related to…

Computer Vision and Pattern Recognition · Computer Science 2024-04-12 Yuanpeng He , Lijian Li

Medical experts often manually segment images to obtain diagnostic statistics and discard the resulting annotations. We aim to train segmentation models to alleviate this burden, but constrained to the retained summary statistics (e.g., the…

Computer Vision and Pattern Recognition · Computer Science 2026-05-06 Omkar Kulkarni , Edward Raff , Tim Oates

Generalizability is seen as one of the major challenges in deep learning, in particular in the domain of medical imaging, where a change of hospital or in imaging routines can lead to a complete failure of a model. To tackle this, we…

Computer Vision and Pattern Recognition · Computer Science 2022-06-01 Birk Torpmann-Hagen , Vajira Thambawita , Kyrre Glette , Pål Halvorsen , Michael A. Riegler

Deep learning has played a major role in the interpretation of dermoscopic images for detecting skin defects and abnormalities. However, current deep learning solutions for dermatological lesion analysis are typically limited in providing…

Computer Vision and Pattern Recognition · Computer Science 2021-07-20 Gun-Hee Lee , Han-Bin Ko , Seong-Whan Lee

We propose an approach to instance-level image segmentation that is built on top of category-level segmentation. Specifically, for each pixel in a semantic category mask, its corresponding instance bounding box is predicted using a deep…

Computer Vision and Pattern Recognition · Computer Science 2016-05-24 Zifeng Wu , Chunhua Shen , Anton van den Hengel

The segmentation of substantial brain lesions is a significant and challenging task in the field of medical image segmentation. Substantial brain lesions in brain imaging exhibit high heterogeneity, with indistinct boundaries between lesion…

Computer Vision and Pattern Recognition · Computer Science 2025-08-07 Hongming Wang , Yifeng Wu , Huimin Huang , Hongtao Wu , Jia-Xuan Jiang , Xiaodong Zhang , Hao Zheng , Xian Wu , Yefeng Zheng , Jinping Xu , Jing Cheng

Quantitative molecular imaging is central to treatment response assessment in oncology, yet clinical practice remains largely dominated by patient-level or limited target-lesion criteria that ignore inter-lesion heterogeneity. This…

Medical Physics · Physics 2026-03-25 Fereshteh Yousefirizi , Jean-Mathieu Beauregard , Arman Rahmim

Stroke lesion volume is a key radiologic measurement for assessing the prognosis of Acute Ischemic Stroke (AIS) patients, which is challenging to be automatically measured on Non-Contrast CT (NCCT) scans. Recent diffusion probabilistic…

Computer Vision and Pattern Recognition · Computer Science 2023-07-19 Jianhai Zhang , Tonghua Wan , Ethan MacDonald , Bijoy Menon , Aravind Ganesh , Qiu Wu

Melanoma is the most deadly form of skin cancer. Tracking the evolution of nevi and detecting new lesions across the body is essential for the early detection of melanoma. Despite prior work on longitudinal tracking of skin lesions in 3D…

Computer Vision and Pattern Recognition · Computer Science 2024-12-25 Wei-Lun Huang , Minghao Xue , Zhiyou Liu , Davood Tashayyod , Jun Kang , Amir Gandjbakhche , Misha Kazhdan , Mehran Armand

Monitoring treatment response in longitudinal studies plays an important role in clinical practice. Accurately identifying lesions across serial imaging follow-up is the core to the monitoring procedure. Typically this incorporates both…

Computer Vision and Pattern Recognition · Computer Science 2021-04-13 Jinzheng Cai , Youbao Tang , Ke Yan , Adam P. Harrison , Jing Xiao , Gigin Lin , Le Lu

Precision medicine is an approach for disease treatment that defines treatment strategies based on the individual characteristics of the patients. Motivated by an open problem in cancer genomics, we develop a novel model that flexibly…

Methodology · Statistics 2023-09-04 Matteo Pedone , Raffaele Argiento , Francesco C. Stingo

Deep learning implemented with convolutional network architectures can exceed specialists' diagnostic accuracy. However, whole-image deep learning trained on a given dataset may not generalize to other datasets. The problem arises because…

Computer Vision and Pattern Recognition · Computer Science 2023-05-17 Norsang Lama , R. Joe Stanley , Anand Nambisan , Akanksha Maurya , Jason Hagerty , William V. Stoecker

In this work, we present LesionLocator, a framework for zero-shot longitudinal lesion tracking and segmentation in 3D medical imaging, establishing the first end-to-end model capable of 4D tracking with dense spatial prompts. Our model…

Computer Vision and Pattern Recognition · Computer Science 2025-03-03 Maximilian Rokuss , Yannick Kirchhoff , Seval Akbal , Balint Kovacs , Saikat Roy , Constantin Ulrich , Tassilo Wald , Lukas T. Rotkopf , Heinz-Peter Schlemmer , Klaus Maier-Hein

Multiple sclerosis lesion activity segmentation is the task of detecting new and enlarging lesions that appeared between a baseline and a follow-up brain MRI scan. While deep learning methods for single-scan lesion segmentation are common,…

Computer Vision and Pattern Recognition · Computer Science 2020-06-02 Nils Gessert , Marcel Bengs , Julia Krüger , Roland Opfer , Ann-Christin Ostwaldt , Praveena Manogaran , Sven Schippling , Alexander Schlaefer

Brain lesions are abnormalities or injuries in brain tissue that are often detectable using magnetic resonance imaging (MRI), which reveals structural changes in the affected areas. This broad definition of brain lesions includes areas of…

Computer Vision and Pattern Recognition · Computer Science 2025-07-09 Omar Zamzam , Haleh Akrami , Anand Joshi , Richard Leahy

In pathology, the spatial distribution and proportions of tissue types are key indicators of disease progression, and are more readily available than fine-grained annotations. However, these assessments are rarely mapped to pixel-wise…

Image and Video Processing · Electrical Eng. & Systems 2026-04-28 Yangping Li , Thomas Pinetz , Michael Hölzel , Marieta Toma , Alexander Effland

In voxel-based neuroimage analysis, lesion features have been the main focus in disease prediction due to their interpretability with respect to the related diseases. However, we observe that there exists another type of features introduced…

Applications · Statistics 2017-06-13 Xinwei Sun , Lingjing Hu , Yuan Yao , Yizhou Wang

In this paper, a Bayesian method for piecewise regression is adapted to handle counting processes data distributed as Poisson. A numerical code in Mathematica is developed and tested analyzing simulated data. The resulting method is…

Data Analysis, Statistics and Probability · Physics 2017-02-21 Diego Sevilla

Automated segmentation of medical imaging is of broad interest to clinicians and machine learning researchers alike. The goal of segmentation is to increase efficiency and simplicity of visualization and quantification of regions of…

Image and Video Processing · Electrical Eng. & Systems 2020-06-04 Shruti Jadon , Owen P. Leary , Ian Pan , Tyler J. Harder , David W. Wright , Lisa H. Merck , Derek L. Merck

Matrix-Assisted Laser Desorption/Ionisation Mass Spectrometry Imaging (MSI) is a powerful technique for spatially resolved molecular profiling and cancer biomarker discovery. Recent advances, including a novel multiomics workflow, enable…

Methodology · Statistics 2025-09-03 Francesco Denti , Cecilia Balocchi , Vanna Denti , Giulia Capitoli