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Medical image segmentation is a challenging task, particularly due to inter- and intra-observer variability, even between medical experts. In this paper, we propose a novel model, called Probabilistic Inter-Observer and iNtra-Observer…

Image and Video Processing · Electrical Eng. & Systems 2023-07-24 Arne Schmidt , Pablo Morales-Álvarez , Rafael Molina

We propose a unified objective function, termed CATMIL, that augments the base segmentation loss with two auxiliary supervision terms operating at different levels. The first term, Component-Adaptive Tversky, reweights voxel contributions…

Computer Vision and Pattern Recognition · Computer Science 2026-04-28 Minh Sao Khue Luu , Evgeniy N. Pavlovskiy , Bair N. Tuchinov

Automatic skin lesion segmentation on dermoscopic images is an essential component in computer-aided diagnosis of melanoma. Recently, many fully supervised deep learning based methods have been proposed for automatic skin lesion…

Computer Vision and Pattern Recognition · Computer Science 2018-08-14 Xiaomeng Li , Lequan Yu , Hao Chen , Chi-Wing Fu , Pheng-Ann Heng

Segmenting small lesions in medical images remains notoriously difficult. Most prior work tackles this challenge by either designing better architectures, loss functions, or data augmentation schemes; and collecting more labeled data. We…

Computer Vision and Pattern Recognition · Computer Science 2025-11-25 Rachit Saluja , Asli Cihangir , Ruining Deng , Johannes C. Paetzold , Fengbei Liu , Mert R. Sabuncu

Lesion detection is an important problem within medical imaging analysis. Most previous work focuses on detecting and segmenting a specialized category of lesions (e.g., lung nodules). However, in clinical practice, radiologists are…

Computer Vision and Pattern Recognition · Computer Science 2020-05-29 Ke Yan , Jinzheng Cai , Adam P. Harrison , Dakai Jin , Jing Xiao , Le Lu

The automatic segmentation of pathological regions within whole-body PET-CT volumes has the potential to streamline various clinical applications such as diagno-sis, prognosis, and treatment planning. This study aims to address this…

Image and Video Processing · Electrical Eng. & Systems 2024-09-24 Mehdi Astaraki , Simone Bendazzoli

Discriminative convolutional neural networks (CNNs), for which a voxel-wise conditional Multinoulli distribution is assumed, have performed well in many brain lesion segmentation tasks. For a trained discriminative CNN to be used in…

Image and Video Processing · Electrical Eng. & Systems 2021-02-22 Kevin Raina

This paper proposes a new methodology to perform Bayesian inference for a class of multidimensional Cox processes in which the intensity function is piecewise constant. Poisson processes with piecewise constant intensity functions are…

Methodology · Statistics 2022-11-16 Flavio B. Gonçalves , Barbara C. C. Dias

Chronic wounds significantly impact quality of life. If not properly managed, they can severely deteriorate. Image-based wound analysis could aid in objectively assessing the wound status by quantifying important features that are related…

Computer Vision and Pattern Recognition · Computer Science 2021-11-03 Gaetano Scebba , Jia Zhang , Sabrina Catanzaro , Carina Mihai , Oliver Distler , Martin Berli , Walter Karlen

Segmentation is a key stage in dermoscopic image processing, where the accuracy of the border line that defines skin lesions is of utmost importance for subsequent algorithms (e.g., classification) and computer-aided early diagnosis of…

Computer Vision and Pattern Recognition · Computer Science 2019-02-21 Pedro M. M. Pereira , Rui Fonseca-Pinto , Rui Pedro Paiva , Luis M. N. Tavora , Pedro A. A. Assuncao , Sergio M. M. de Faria

Deep convolutional neural networks are widely used in medical image segmentation but require many labeled images for training. Annotating three-dimensional medical images is a time-consuming and costly process. To overcome this limitation,…

Computer Vision and Pattern Recognition · Computer Science 2024-07-08 Weiyi Xie , Nathalie Willems , Nikolas Lessmann , Tom Gibbons , Daniele De Massari

Poisson regression is a popular tool for modeling count data and is applied in a vast array of applications from the social to the physical sciences and beyond. Real data, however, are often over- or under-dispersed and, thus, not conducive…

Applications · Statistics 2010-11-10 Kimberly F. Sellers , Galit Shmueli

Large-scale datasets with high-quality labels are desired for training accurate deep learning models. However, due to the annotation cost, datasets in medical imaging are often either partially-labeled or small. For example, DeepLesion is…

Computer Vision and Pattern Recognition · Computer Science 2021-01-05 Ke Yan , Jinzheng Cai , Youjing Zheng , Adam P. Harrison , Dakai Jin , Youbao Tang , Yuxing Tang , Lingyun Huang , Jing Xiao , Le Lu

Machine learning holds tremendous promise for transforming the fundamental practice of scientific discovery by virtue of its data-driven nature. With the ever-increasing stream of research data collection, it would be appealing to…

Machine Learning · Computer Science 2024-03-06 Jianan Fan , Dongnan Liu , Hang Chang , Heng Huang , Mei Chen , Weidong Cai

A major interest in longitudinal neuroimaging studies involves investigating voxel-level neuroplasticity due to treatment and other factors across visits. However, traditional voxel-wise methods are beset with several pitfalls, which can…

Neurons and Cognition · Quantitative Biology 2023-10-19 Suprateek Kundu , Alec Reinhardt , Serena Song , Joo Han , M. Lawson Meadows , Bruce Crosson , Venkatagiri Krishnamurthy

Generalized linear regressions, such as logistic regressions or Poisson regressions, are long-studied regression analysis approaches, and their applications are widely employed in various classification problems. Our study considers a…

Machine Learning · Statistics 2024-01-17 Vu Duc Anh , Tran Anh Tuan , Tran Ngoc Thang , Nguyen Thi Ngoc Anh

Brain lesion segmentation provides a valuable tool for clinical diagnosis, and convolutional neural networks (CNNs) have achieved unprecedented success in the task. Data augmentation is a widely used strategy that improves the training of…

Image and Video Processing · Electrical Eng. & Systems 2021-09-29 Xinru Zhang , Chenghao Liu , Ni Ou , Xiangzhu Zeng , Xiaoliang Xiong , Yizhou Yu , Zhiwen Liu , Chuyang Ye

Neural demyelination and brain damage accumulated in white matter appear as hyperintense areas on T2-weighted MRI scans in the form of lesions. Modeling binary images at the population level, where each voxel represents the existence of a…

Methodology · Statistics 2023-05-29 Anna Menacher , Thomas E. Nichols , Chris Holmes , Habib Ganjgahi

Early and accurate diagnosis and lesion localization of bone infections are crucial for clinical treatment. PET-CT integrates anatomical information from CT with metabolic information from PET, making it an important imaging modality for…

Computer Vision and Pattern Recognition · Computer Science 2026-05-19 Zonglin Yang , Xiaolei Diao , Jishizhan Chen , Xiaozhuang Man , Wei Kong , Gen Wen , Pengfei Cheng , Daqian Shi

Skin lesion segmentation is one of the crucial steps for an efficient non-invasive computer-aided early diagnosis of melanoma. This paper investigates how color information, besides saliency, can be used to determine the pigmented lesion…

Image and Video Processing · Electrical Eng. & Systems 2021-11-08 Giuliana Ramella
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