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Computer-aided diagnosis (CAD), a vibrant medical imaging research field, is expanding quickly. Because errors in medical diagnostic systems might lead to seriously misleading medical treatments, major efforts have been made in recent years…

Machine Learning · Computer Science 2023-08-04 Farzaneh Tajidini , Mohammad-Javad Kheiri

Multiple sclerosis is an inflammatory autoimmune demyelinating disease that is characterized by lesions in the central nervous system. Typically, magnetic resonance imaging (MRI) is used for tracking disease progression. Automatic image…

Image and Video Processing · Electrical Eng. & Systems 2020-08-06 Nils Gessert , Julia Krüger , Roland Opfer , Ann-Christin Ostwaldt , Praveena Manogaran , Hagen H. Kitzler , Sven Schippling , Alexander Schlaefer

Breast ultrasound imaging is a valuable tool for early breast cancer detection, but automated tumor segmentation is challenging due to inherent noise, variations in scale of lesions, and fuzzy boundaries. To address these challenges, we…

Image and Video Processing · Electrical Eng. & Systems 2025-06-23 Muhammad Azeem Aslam , Asim Naveed , Nisar Ahmed

Medical image segmentation assists in computer-aided diagnosis, surgeries, and treatment. Digitize tissue slide images are used to analyze and segment glands, nuclei, and other biomarkers which are further used in computer-aided medical…

Image and Video Processing · Electrical Eng. & Systems 2022-09-05 Saad Wazir , Muhammad Moazam Fraz

Skin lesion segmentation is a critical task in computer-aided diagnosis systems for dermatological diseases. Accurate segmentation of skin lesions from medical images is essential for early detection, diagnosis, and treatment planning. In…

Computer Vision and Pattern Recognition · Computer Science 2024-05-07 Viet-Thanh Nguyen , Van-Truong Pham , Thi-Thao Tran

With the development of computer-aided diagnosis (CAD) and image scanning technology, Whole-slide Image (WSI) scanners are widely used in the field of pathological diagnosis. Therefore, WSI analysis has become the key to modern digital…

Computer Vision and Pattern Recognition · Computer Science 2021-02-23 Chen Li , Xintong Li , Md Rahaman , Xiaoyan Li , Hongzan Sun , Hong Zhang , Yong Zhang , Xiaoqi Li , Jian Wu , Yudong Yao , Marcin Grzegorzek

Deep learning techniques have shown their superior performance in dermatologist clinical inspection. Nevertheless, melanoma diagnosis is still a challenging task due to the difficulty of incorporating the useful dermatologist clinical…

Image and Video Processing · Electrical Eng. & Systems 2021-12-03 Xiaohong Wang , Xudong Jiang , Henghui Ding , Yuqian Zhao , Jun Liu

Accurate diagnostics of a skin lesion is a critical task in classification dermoscopic images. In this research, we form a new type of image features, called hybrid features, which has stronger discrimination ability than single method…

Image and Video Processing · Electrical Eng. & Systems 2021-12-21 Redha Ali , Hussin K. Ragb

Age-related macular degeneration (AMD) is a degenerative disorder affecting the macula, a key area of the retina for visual acuity. Nowadays, it is the most frequent cause of blindness in developed countries. Although some promising…

Image and Video Processing · Electrical Eng. & Systems 2022-12-06 José Morano , Álvaro S. Hervella , José Rouco , Jorge Novo , José I. Fernández-Vigo , Marcos Ortega

In this paper, we present an automated approach for segmenting multiple sclerosis (MS) lesions from multi-modal brain magnetic resonance images. Our method is based on a deep end-to-end 2D convolutional neural network (CNN) for slice-based…

Computer Vision and Pattern Recognition · Computer Science 2019-04-09 Shahab Aslani , Michael Dayan , Loredana Storelli , Massimo Filippi , Vittorio Murino , Maria A Rocca , Diego Sona

The analysis of fundus images is critical for the early detection and diagnosis of retinal diseases such as Diabetic Retinopathy (DR), Glaucoma, and Age-related Macular Degeneration (AMD). Traditional diagnostic workflows, however, often…

Computer Vision and Pattern Recognition · Computer Science 2025-07-31 Faisal Ahmed

Deep learning models show promise in digital pathology, but their opaque decision-making processes limit trust and clinical adoption. To address this challenge, we present HIPPO, an explainable AI method for analyzing weakly-supervised…

Tissues and Organs · Quantitative Biology 2025-12-10 Jakub R. Kaczmarzyk , Chanwoo Kim , Soham Gadgil , Deepika Savant , Zhen Zhao , Joel H. Saltz , Su-In Lee , Peter K. Koo

Early diagnosis is essential for the successful treatment of bowel cancers including colorectal cancer (CRC) and capsule endoscopic imaging with robotic actuation can be a valuable diagnostic tool when combined with automated image…

The utilisation of deep learning segmentation algorithms that learn complex organs and tissue patterns and extract essential regions of interest from the noisy background to improve the visual ability for medical image diagnosis has…

Computer Vision and Pattern Recognition · Computer Science 2023-11-03 Yanming Guo

The computer-aided detection (CADe) systems are developed to assist pathologists in slide assessment, increasing diagnosis efficiency and reducing missing inspections. Many studies have shown such a CADe system with deep learning approaches…

Computer Vision and Pattern Recognition · Computer Science 2019-03-05 Wei-Wen Hsu , Chung-Hao Chen , Chang Hoa , Yu-Ling Hou , Xiang Gao , Yun Shao , Xueli Zhang , Jingjing Wang , Tao He , Yanghong Tai

Optical coherence tomography (OCT) is widely used for diagnosing and monitoring retinal diseases, such as age-related macular degeneration (AMD). The segmentation of biomarkers such as layers and lesions is essential for patient diagnosis…

Computer Vision and Pattern Recognition · Computer Science 2025-09-26 Botond Fazekas , Guilherme Aresta , Philipp Seeböck , Julia Mai , Ursula Schmidt-Erfurth , Hrvoje Bogunović

Parotid gland lesion segmentation is essential for the treatment of parotid gland diseases. However, due to the variable size and complex lesion boundaries, accurate parotid gland lesion segmentation remains challenging. Recently, the…

Computer Vision and Pattern Recognition · Computer Science 2025-08-14 Zhongyuan Wu , Chuan-Xian Ren , Yu Wang , Xiaohua Ban , Jianning Xiao , Xiaohui Duan

Multiplex Imaging (MI) enables the simultaneous visualization of multiple biological markers in separate imaging channels at subcellular resolution, providing valuable insights into cell-type heterogeneity and spatial organization. However,…

Image and Video Processing · Electrical Eng. & Systems 2024-11-07 Simon Gutwein , Daria Lazic , Thomas Walter , Sabine Taschner-Mandl , Roxane Licandro

PET and CT are two modalities widely used in medical image analysis. Accurately detecting and segmenting lymphomas from these two imaging modalities are critical tasks for cancer staging and radiotherapy planning. However, this task is…

Image and Video Processing · Electrical Eng. & Systems 2021-04-28 Ling Huang , Su Ruan , Pierre Decazes , Thierry Denoeux

Diabetic retinopathy is one of the leading causes of preventable blindness in the world. Its earliest sign are red lesions, a general term that groups both microaneurysms and hemorrhages. In daily clinical practice, these lesions are…

Computer Vision and Pattern Recognition · Computer Science 2017-10-16 José Ignacio Orlando , Elena Prokofyeva , Mariana del Fresno , Matthew B. Blaschko