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Integer linear programming (ILP) is an elegant approach to solve linear optimization problems, naturally described using integer decision variables. Within the context of physics-inspired machine learning applied to chemistry, we…

Integer linear programming (ILP) encompasses a very important class of optimization problems that are of great interest to both academia and industry. Several algorithms are available that attempt to explore the solution space of this class…

Emerging Technologies · Computer Science 2018-08-31 Fabio L. Traversa , Massimiliano Di Ventra

Mixed Integer Linear Programs (MILPs) are essential tools for solving planning and scheduling problems across critical industries such as construction, manufacturing, and logistics. However, their widespread adoption is limited by long…

Machine Learning · Computer Science 2025-06-10 Xiaoke Wang , Batuhan Altundas , Zhaoxin Li , Aaron Zhao , Matthew Gombolay

Mixed-integer programming (MIP) is a well-established framework for computer-aided molecular design (CAMD). By precisely encoding the molecular space and score functions, e.g., a graph neural network, the molecular design problem is…

Computational Engineering, Finance, and Science · Computer Science 2024-11-26 Shiqiang Zhang , Christian W. Feldmann , Frederik Sandfort , Miriam Mathea , Juan S. Campos , Ruth Misener

This applied research article explores the application of Mixed-Integer Linear Programming (MILP) to address line-balancing challenges in the garment industry, focusing on optimizing production processes under multiple constraints. By…

Optimization and Control · Mathematics 2025-04-10 Ray Wai Man Kong , Ding Ning , Theodore Ho Tin Kong

In this paper, we propose a new mixed-integer linear programming (MILP) model ontology and a novel constraint typology of MILP formulations. MILP is a commonly used mathematical programming technique for modelling and solving real-life…

Artificial Intelligence · Computer Science 2021-03-02 Bahadorreza Ofoghi , Vicky Mak , John Yearwood

Mixed-integer linear programming (MILP) is widely employed for modeling combinatorial optimization problems. In practice, similar MILP instances with only coefficient variations are routinely solved, and machine learning (ML) algorithms are…

Optimization and Control · Mathematics 2023-03-07 Qingyu Han , Linxin Yang , Qian Chen , Xiang Zhou , Dong Zhang , Akang Wang , Ruoyu Sun , Xiaodong Luo

Leveraging machine learning (ML) to predict an initial solution for mixed-integer linear programming (MILP) has gained considerable popularity in recent years. These methods predict a solution and fix a subset of variables to reduce the…

Machine Learning · Computer Science 2025-03-04 Haoyang Liu , Jie Wang , Zijie Geng , Xijun Li , Yuxuan Zong , Fangzhou Zhu , Jianye Hao , Feng Wu

Quantum computing is rapidly advancing, harnessing the power of qubits' superposition and entanglement for computational advantages over classical systems. However, scalability poses a primary challenge for these machines. By implementing a…

Emerging quantum computing technologies, such as Noisy Intermediate-Scale Quantum (NISQ) devices, offer potential advancements in solving mathematical optimization problems. However, limitations in qubit availability, noise, and errors pose…

Finding optimal join orders is among the most crucial steps to be performed by query optimisers. Though extensively studied in data management research, the problem remains far from solved: While query optimisers rely on exhaustive search…

Databases · Computer Science 2025-10-24 Manuel Schönberger , Immanuel Trummer , Wolfgang Mauerer

Edge computing is a promising technology that offers a superior user experience and enables various innovative Internet of Things applications. In this paper, we present a mixed-integer linear programming (MILP) model for optimal edge…

Quantum Physics · Physics 2023-06-05 Duong The Do , Ni Trieu , Duong Tung Nguyen

Ising machines are a form of quantum-inspired processing-in-memory computer which has shown great promise for overcoming the limitations of traditional computing paradigms while operating at a fraction of the energy use. The process of…

Optimization and Control · Mathematics 2025-07-18 Isaac K. Martin , Andrew G. Moore , John T. Daly , Jess J. Meyer , Teresa M. Ranadive

We propose a new approach to utilize quantum computers for binary linear programming (BLP), which can be extended to general integer linear programs (ILP). Quantum optimization algorithms, hybrid or quantum-only, are currently general…

Data Structures and Algorithms · Computer Science 2026-02-13 András Czégel , Boglárka G. -Tóth

Mixed Integer Linear Programming (MILP) is a fundamental tool for modeling combinatorial optimization problems. Recently, a growing body of research has used machine learning to accelerate MILP solving. Despite the increasing popularity of…

Machine Learning · Computer Science 2024-10-29 Weimin Huang , Taoan Huang , Aaron M Ferber , Bistra Dilkina

In this study, we introduce an innovative deep learning framework that employs a transformer model to address the challenges of mixed-integer programs, specifically focusing on the Capacitated Lot Sizing Problem (CLSP). Our approach, to our…

Artificial Intelligence · Computer Science 2024-05-27 Joshua F. Cooper , Seung Jin Choi , I. Esra Buyuktahtakin

Constraint Programming (CP) users need significant expertise in order to model their problems appropriately, notably to select propagators and search strategies. This puts the brakes on a broader uptake of CP. In this paper, we introduce…

Artificial Intelligence · Computer Science 2016-11-29 Thierry Petit

Cutting planes (cuts) are crucial for solving Mixed Integer Linear Programming (MILP) problems. Advanced MILP solvers typically rely on manually designed heuristic algorithms for cut selection, which require much expert experience and…

Optimization and Control · Mathematics 2024-12-11 Xuefeng Zhang , Liangyu Chen , Zhengfeng Yang , Zhenbing Zeng

Model reduction, which aims to learn a simpler model of the original mixed integer linear programming (MILP), can solve large-scale MILP problems much faster. Most existing model reduction methods are based on variable reduction, which…

Machine Learning · Computer Science 2026-02-04 Jiajun Li , Yixuan Li , Ran Hou , Yu Ding , Shisi Guan , Jiahui Duan , Xiongwei Han , Tao Zhong , Vincent Chau , Weiwei Wu , Wanyuan Wang

Mixed Integer Linear Programs (MILP) are well known to be NP-hard (Non-deterministic Polynomial-time hard) problems in general. Even though pure optimization-based methods, such as constraint generation, are guaranteed to provide an optimal…

Optimization and Control · Mathematics 2022-07-18 Asunción Jiménez-Cordero , Juan Miguel Morales , Salvador Pineda