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Transcranial ultrasound imaging is usually limited by skull-induced attenuation and high-order aberrations. By using contrast agents such as microbubbles in combination with ultrafast imaging, not only can the signal-to-noise ratio be…

Ultrasound localization microscopy offers new radiation-free diagnostic tools for vascular imaging deep within the tissue. Sequential localization of echoes returned from inert microbubbles with low-concentration within the bloodstream…

Medical Physics · Physics 2018-04-11 Oren Solomon , Ruud J. G. van Sloun , Hessel Wijkstra , Massimo Mischi , Yonina C. Eldar

Super-resolution ultrasound imaging with ultrasound localization microscopy (ULM) offers a high-resolution view of microvascular structures. Yet, ULM image quality heavily relies on precise microbubble (MB) detection. Despite the crucial…

Artificial Intelligence · Computer Science 2026-01-15 Sepideh K. Gharamaleki , Brandon Helfield , Hassan Rivaz

Mapping blood microflows of the whole brain is crucial for early diagnosis of cerebral diseases. Ultrasound localization microscopy (ULM) was recently applied to map and quantify blood microflows in 2D in the brain of adult patients down to…

Medical Physics · Physics 2023-04-12 Hugues Favre , Mathieu Pernot , Mickael Tanter , Clément Papadacci

Super-Resolution Ultrasound (SRUS) imaging through localising and tracking microbubbles, also known as Ultrasound Localisation Microscopy (ULM), has demonstrated significant potential for reconstructing microvasculature and flows with…

Image and Video Processing · Electrical Eng. & Systems 2025-03-26 Jipeng Yan , Qingyuan Tan , Shusei Kawara , Jingwen Zhu , Bingxue Wang , Matthieu Toulemonde , Honghai Liu , Ying Tan , Meng-Xing Tang

Ultrasound Localization Microscopy (ULM) offers a cost-effective modality for microvascular imaging by using intravascular contrast agents (microbubbles). However, ULM has a fundamental trade-off between acquisition time and spatial…

Signal Processing · Electrical Eng. & Systems 2021-01-26 Ufuk Soylu , Yoram Bresler

We propose a novel deep-learning framework for super-resolution ultrasound images and videos in terms of spatial resolution and line reconstruction. We up-sample the acquired low-resolution image through a vision-based interpolation method;…

Computer Vision and Pattern Recognition · Computer Science 2023-05-03 Simone Cammarasana , Paolo Nicolardi , Giuseppe Patanè

We present an ultra-fast, precise, parameter-free method, which we term Deep-STORM, for obtaining super-resolution images from stochastically-blinking emitters, such as fluorescent molecules used for localization microscopy. Deep-STORM uses…

Optics · Physics 2018-05-03 Elias Nehme , Lucien E. Weiss , Tomer Michaeli , Yoav Shechtman

Super-resolution reconstruction techniques entail the utilization of software algorithms to transform one or more sets of low-resolution images captured from the same scene into high-resolution images. In recent years, considerable…

Computer Vision and Pattern Recognition · Computer Science 2024-08-02 Hao Yan , Zixiang Wang , Zhengjia Xu , Zhuoyue Wang , Zhizhong Wu , Ranran Lyu

Diffusion-weighted magnetic resonance imaging (DW-MRI) can be used to characterise the microstructure of the nervous tissue, e.g. to delineate brain white matter connections in a non-invasive manner via fibre tracking. Magnetic Resonance…

Depth image super-resolution is an extremely challenging task due to the information loss in sub-sampling. Deep convolutional neural network have been widely applied to color image super-resolution. Quite surprisingly, this success has not…

Computer Vision and Pattern Recognition · Computer Science 2016-07-08 Xibin Song , Yuchao Dai , Xueying Qin

Ultrasound localization microscopy (ULM) enables microvascular imaging at spatial resolutions beyond the acoustic diffraction limit, offering significant clinical potentials. However, ULM performance relies heavily on microbubble (MB)…

Ultrafast ultrasound (US) revolutionized biomedical imaging with its capability of acquiring full-view frames at over 1 kHz, unlocking breakthrough modalities such as shear-wave elastography and functional US neuroimaging. Yet, it suffers…

Image and Video Processing · Electrical Eng. & Systems 2022-04-04 Dimitris Perdios , Manuel Vonlanthen , Florian Martinez , Marcel Arditi , Jean-Philippe Thiran

Convection of liquid metals drives large natural processes and is important in technical processes. Model experiments are conducted for research purposes where simulations are expensive and the clarification of open questions requires novel…

Fluid Dynamics · Physics 2024-04-18 David Weik , Zehua Dou , Dirk Räbiger , Tobias Vogt , Sven Eckert , Jürgen Czarske , Lars Büttner

Magnetic resonance imaging (MRI) is extensively used for diagnosis and image-guided therapeutics. Due to hardware, physical and physiological limitations, acquisition of high-resolution MRI data takes long scan time at high system cost, and…

Medical Physics · Physics 2018-10-17 Qing Lyu , Chenyu You , Hongming Shan , Ge Wang

Convolutional Neural Networks (CNNs) have been consistently proved state-of-the-art results in image Super-Resolution (SR), representing an exceptional opportunity for the remote sensing field to extract further information and knowledge…

Image and Video Processing · Electrical Eng. & Systems 2020-11-02 Francesco Salvetti , Vittorio Mazzia , Aleem Khaliq , Marcello Chiaberge

Three-dimensional ultrasound localization microscopy (ULM) enables comprehensive visualization of the vasculature, thereby improving diagnostic reliability. Nevertheless, its clinical translation remains challenging, as the exponential…

Single-Molecule Localization Microscopy (SMLM) has expanded our ability to visualize subcellular structures but is limited in its temporal resolution. Increasing emitter density will improve temporal resolution, but current analysis…

Signal Processing · Electrical Eng. & Systems 2023-05-10 Armin Abdehkakha , Craig Snoeyink

Ultrasound Localization Microscopy (ULM) relies on the injection of microbubbles (MBs) to obtain highly resolved density maps of blood circulation in vivo, with a resolution that can reach 10 {\mu}m ~ {\lambda}/10 in the rodent brain.…

In portable, three dimensional, and ultra-fast ultrasound imaging systems, there is an increasing demand for the reconstruction of high quality images from a limited number of radio-frequency (RF) measurements due to receiver (Rx) or…

Computer Vision and Pattern Recognition · Computer Science 2018-08-08 Yeo Hun Yoon , Shujaat Khan , Jaeyoung Huh , Jong Chul Ye