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Purpose: Magnetic Resonance Imaging (MRI) enables non-invasive assessment of brain abnormalities during early life development. Permanent magnet scanners operating in the neonatal intensive care unit (NICU) facilitate MRI of sick infants,…

Image and Video Processing · Electrical Eng. & Systems 2025-05-23 Yamin Arefeen , Brett Levac , Bhairav Patel , Chang Ho , Jonathan I. Tamir

Recent advances in neuroimaging analysis have enabled accurate decoding of mental state from brain activation patterns during functional magnetic resonance imaging scans. A commonly applied tool for this purpose is principal components…

Machine Learning · Statistics 2025-09-10 Jared Rieck , Julia Wrobel , Joshua L. Gowin , Yue Wang , Martin Paulus , Ryan Peterson

Diffusion models now set the benchmark in high-fidelity generative sampling, yet they can, in principle, be prone to memorization. In this case, their learned score overfits the finite dataset so that the reverse-time SDE samples are mostly…

Machine Learning · Computer Science 2025-05-30 Franck Gabriel , François Ged , Maria Han Veiga , Emmanuel Schertzer

Diffusion MRI (dMRI) is essential for studying brain microstructure, but high-resolution imaging remains challenging due to the inherent trade-offs between acquisition time and signal-to-noise ratio (SNR). Conventional methods often…

Image and Video Processing · Electrical Eng. & Systems 2025-05-20 Yinzhe Wu , Jiahao Huang , Fanwen Wang , Mengze Gao , Congyu Liao , Guang Yang , Kawin Setsompop

Random matrix theory (RMT) combined with principal component analysis has resulted in a widely used MPPCA noise mapping and denoising algorithm, that utilizes the redundancy in multiple acquisitions and in local image patches. RMT-based…

Nuclear Magnetic Resonance (NMR) spectroscopy is an important analytical tool in chemistry, biology, and life science, but it suffers from relatively low sensitivity and long acquisition time. Thus, improving the apparent signal-to-noise…

Chemical Physics · Physics 2020-07-27 Tianyu Qiu , Zi Wang , Huiting Liu , Di Guo , Xiaobo Qu

The denoising of magnetic resonance (MR) images is a task of great importance for improving the acquired image quality. Many methods have been proposed in the literature to retrieve noise free images with good performances. Howerever, the…

Computer Vision and Pattern Recognition · Computer Science 2018-02-01 Dongsheng Jiang , Weiqiang Dou , Luc Vosters , Xiayu Xu , Yue Sun , Tao Tan

Prostate cancer (PCa) is one of the leading causes of death for men worldwide. Multi-parametric magnetic resonance (mpMR) imaging has emerged as a non-invasive diagnostic tool for detecting and localising prostate tumours by specialised…

Image and Video Processing · Electrical Eng. & Systems 2021-06-07 Zhe Min , Fernando J. Bianco , Qianye Yang , Rachael Rodell , Wen Yan , Dean Barratt , Yipeng Hu

We study the problem of estimating a large, low-rank matrix corrupted by additive noise of unknown covariance, assuming one has access to additional side information in the form of noise-only measurements. We study the Whiten-Shrink-reColor…

Statistics Theory · Mathematics 2023-07-18 Matan Gavish , William Leeb , Elad Romanov

The robust principal component analysis (RPCA), which aims to estimate underlying low-rank and sparse structures from the degraded observation data, has found wide applications in computer vision. It is usually replaced by the principal…

Computer Vision and Pattern Recognition · Computer Science 2019-08-20 Huiwen Dong , Jing Yu , Chuangbai Xiao

Magnetic Resonance Imaging (MRI), including diffusion MRI (dMRI), serves as a ``microscope'' for anatomical structures and routinely mitigates the influence of low signal-to-noise ratio scans by compromising temporal or spatial resolution.…

Image and Video Processing · Electrical Eng. & Systems 2025-03-11 Chenxu Wu , Qingpeng Kong , Zihang Jiang , S. Kevin Zhou

In our previous work, a reduced order model (ROM) for a stochastic system was made, where noisy data was projected onto principal component analysis (PCA)-derived basis vectors to obtain an accurate reconstruction of the noise-free data.…

Numerical Analysis · Mathematics 2017-02-07 Indika Udagedara , Brian Helenbrook , Aaron Luttman , Jared Catenacci

Principal Component Analysis (PCA) is a very successful dimensionality reduction technique, widely used in predictive modeling. A key factor in its widespread use in this domain is the fact that the projection of a dataset onto its first…

Machine Learning · Statistics 2017-05-19 Xianghui Luo , Robert J. Durrant

In this paper, we study the problem of computing a Principal Component Analysis of data affected by Poisson noise. We assume samples are drawn from independent Poisson distributions. We want to estimate principle components of a fixed…

Methodology · Statistics 2021-05-25 Toby Kenney , Tianshu Huang , Hong Gu

To develop and evaluate a new deep learning MR denoising method that leverages quantitative noise distribution information from the reconstruction process to improve denoising performance and generalization. This retrospective study trained…

The proliferation of imaging devices and countless image data generated every day impose an increasingly high demand on efficient and effective image denoising. In this paper, we establish a theoretical connection between principal…

Computer Vision and Pattern Recognition · Computer Science 2025-12-30 Zhaoming Kong , Xiaowei Yang , Jiahuan Zhang

Principal component analysis (PCA) is arguably the most widely used dimension-reduction method for vector-type data. When applied to a sample of images, PCA requires vectorization of the image data, which in turn entails solving an…

Image and Video Processing · Electrical Eng. & Systems 2021-03-02 Szu-Chi Chung , Shao-Hsuan Wang , Po-Yao Niu , Su-Yun Huang , Wei-Hau Chang , I-Ping Tu

Diffusion Probabilistic Models have demonstrated remarkable performance across a wide range of generative tasks. However, we have observed that these models often suffer from a Signal-to-Noise Ratio-timestep (SNR-t) bias. This bias refers…

Computer Vision and Pattern Recognition · Computer Science 2026-04-20 Meng Yu , Lei Sun , Jianhao Zeng , Xiangxiang Chu , Kun Zhan

In many scientific applications, measured time series are corrupted by noise or distortions. Traditional denoising techniques often fail to recover the signal of interest, particularly when the signal-to-noise ratio is low or when certain…

Machine Learning · Computer Science 2022-11-02 Natalie Klein , Amber J. Day , Harris Mason , Michael W. Malone , Sinead A. Williamson

Hyperspectral optical imaging provides rich spectral information for estimating continuous environmental and material parameters; however, its high dimensionality and strong feature correlation pose significant challenges for machine…

Optics · Physics 2025-12-18 Parisa Parand , Mahmoud Samadpour