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Multiple sclerosis is a disease that affects the brain and spinal cord, it can lead to severe disability and has no known cure. The majority of prior work in machine learning for multiple sclerosis has been centered around using Magnetic…

Machine Learning · Computer Science 2023-09-12 Alexander Norcliffe , Lev Proleev , Diana Mincu , Fletcher Lee Hartsell , Katherine Heller , Subhrajit Roy

Multiple sclerosis (MS) is a chronic autoimmune disease that affects the central nervous system. The progression and severity of MS varies by individual, but it is generally a disabling disease. Although medications have been developed to…

Applications · Statistics 2013-03-06 Joyce C. Ho , Joydeep Ghosh , KP Unnikrishnan

Early multiple sclerosis (MS) disability progression prediction is challenging due to disease heterogeneity. This work predicts 48- and 72-week disability using sparse baseline clinical data and 12 weeks of daily digital Floodlight data…

Machine Learning · Computer Science 2025-06-19 Maxime Usdin , Lito Kriara , Licinio Craveiro

Personalized longitudinal disease assessment is central to quickly diagnosing, appropriately managing, and optimally adapting the therapeutic strategy of multiple sclerosis (MS). It is also important for identifying the idiosyncratic…

Multiple sclerosis (MS) affects the central nervous system with a wide range of symptoms. MS can, for example, cause pain, changes in mood and fatigue, and may impair a person's movement, speech and visual functions. Diagnosis of MS…

Computers and Society · Computer Science 2020-12-03 Patrick Schwab , Walter Karlen

Multiple Sclerosis (MS) is a chronic disease characterized by progressive or alternate impairment of neurological functions (motor, sensory, visual, and cognitive). Predicting disease progression with a probabilistic and time-dependent…

Background: An early diagnosis together with an accurate disease progression monitoring of multiple sclerosis is an important component of successful disease management. Prior studies have established that multiple sclerosis is correlated…

Audio and Speech Processing · Electrical Eng. & Systems 2021-09-28 Emil Svoboda , Tomáš Bořil , Jan Rusz , Tereza Tykalová , Dana Horáková , Charles R. G. Guttman , Krastan B. Blagoev , Hiroto Hatabu , Vlad I. Valtchinov

Multiple Sclerosis is a degenerative condition of the central nervous system that affects nearly 2.5 million of individuals in terms of their physical, cognitive, psychological and social capabilities. Researchers are currently…

Machine Learning · Statistics 2016-12-05 Samuele Fiorini , Andrea Tacchino , Giampaolo Brichetto , Alessandro Verri , Annalisa Barla

Parkinson's disease is a neurodegenerative disease that can affect a person's movement, speech, dexterity, and cognition. Clinicians primarily diagnose Parkinson's disease by performing a clinical assessment of symptoms. However,…

Neurons and Cognition · Quantitative Biology 2018-11-16 Patrick Schwab , Walter Karlen

Multiple Sclerosis (MS) is a chronic disease developed in human brain and spinal cord, which can cause permanent damage or deterioration of the nerves. The severity of MS disease is monitored by the Expanded Disability Status Scale (EDSS),…

Machine Learning · Computer Science 2023-04-11 Kai Zhang , John A. Lincoln , Xiaoqian Jiang , Elmer V. Bernstam , Shayan Shams

Stroke remains one of the most critical global health challenges, ranking as the second leading cause of death and the third leading cause of disability worldwide. This study explores the effectiveness of machine learning algorithms in…

Machine Learning · Computer Science 2025-05-16 Anastasija Tashkova , Stefan Eftimov , Bojan Ristov , Slobodan Kalajdziski

Parkinson's disease (PD) is a common neurological disorder characterized by gait impairment. PD has no cure, and an impediment to developing a treatment is the lack of any accepted method to predict disease progression rate. The primary aim…

Signal Processing · Electrical Eng. & Systems 2019-11-26 Vyom Raval , Kevin P. Nguyen , Ashley Gerald , Richard B. Dewey , Albert Montillo

Parkinsons Disease (PD) is a progressive neurological disorder that primarily affects motor functions and can lead to mild cognitive impairment (MCI) and dementia in its advanced stages. With approximately 10 million people diagnosed…

Image and Video Processing · Electrical Eng. & Systems 2025-05-02 Abu Saleh Musa Miah , taro Suzuki , Jungpil Shin

Accurate diagnosis of Parkinson disease, especially in its early stages, can be a challenging task. The application of machine learning techniques helps improve the diagnostic accuracy of Parkinson disease detection but only few studies…

Machine Learning · Computer Science 2024-12-25 Majid Ali , Hina Shakir , Asia Samreen , Sohaib Ahmed

Parkinson's disease (PD) is one of the major public health problems in the world. It is a well-known fact that around one million people suffer from Parkinson's disease in the United States whereas the number of people suffering from…

Machine Learning · Computer Science 2016-10-27 Kamal Nayan Reddy Challa , Venkata Sasank Pagolu , Ganapati Panda , Babita Majhi

Multiple sclerosis (MS) is a progressive inflammatory and neurodegenerative disease of the central nervous system affecting over 2.5 million people globally. In-clinic six-minute walk test (6MWT) is a widely used objective measure to…

Multiple sclerosis is a chronic autoimmune disease that affects the central nervous system. Understanding multiple sclerosis progression and identifying the implicated brain structures is crucial for personalized treatment decisions.…

Machine Learning (ML) algorithms are vital for supporting clinical decision-making in biomedical informatics. However, their predictive performance can vary across demographic groups, often due to the underrepresentation of historically…

Machine Learning · Computer Science 2025-03-04 Ioannis Bilionis , Ricardo C. Berrios , Luis Fernandez-Luque , Carlos Castillo

Prognosis on the occurrence of relapses in individuals with Relapsing-Remitting Multiple Sclerosis (RRMS), the most common subtype of Multiple Sclerosis (MS), could support individualized decisions and disease management and could be…

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