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We investigate multi-physical topology optimization for microfluidic mixers employing the phase-field model. The optimization problem is formulated using a modified Ginzburg-Landau free energy functional. To eliminate fluid blockage in…

Optimization and Control · Mathematics 2025-10-23 Zongyuan Liu , Jiajie Li , Shengfeng Zhu

We introduce a new diffuse interface model for tumour growth in the presence of a nutrient, in which we take into account mechanical effects and reversible tissue damage. The highly nonlinear PDEs system mainly consists of a Cahn-Hilliard…

Analysis of PDEs · Mathematics 2025-10-09 Giulia Cavalleri

In this work, we develop a fully implicit Hybrid High-Order algorithm for the Cahn-Hilliard problem in mixed form. The space discretization hinges on local reconstruction operators from hybrid polynomial unknowns at elements and faces. The…

Numerical Analysis · Mathematics 2016-07-01 Florent Chave , Daniele A. Di Pietro , Fabien Marche , Franck Pigeonneau

In this work, we design and analyze semi/fully-discrete virtual element approximations for the time-dependent Navier--Stokes-Cahn--Hilliard equations, modeling the dynamics of two-phase incompressible fluid flows with diffuse interfaces. A…

Numerical Analysis · Mathematics 2026-01-27 Alberth Silgado , Giuseppe Vacca

We provide a detailed mathematical analysis of a model for phase separation on biological membranes which was recently proposed by Garcke, R\"atz, R\"oger and the second author. The model is an extended Cahn-Hilliard equation which contains…

Analysis of PDEs · Mathematics 2019-02-06 Helmut Abels , Johannes Kampmann

We describe a mathematical model for heterojunctions in semiconductors which can be used, e.g., for modeling higher efficiency solar cells. The continuum model involves well-known drift-diffusion equations posed away from the interface.…

Computational Physics · Physics 2013-09-10 David H. Foster , Timothy Costa , Malgorzata Peszynska , Guenter Schneider

In this work, we study a phase-field model for curvature-driven pattern formation in biomembranes. The model is derived as a gradient flow of an energy functional that approximates the two-phase Canham--Helfrich energy. This leads to a…

Analysis of PDEs · Mathematics 2025-11-27 Patrik Knopf , Anastasija Pešić , Dennis Trautwein

In this work, we develop an $\mathcal{O}(N)$ implicit real space method in 1D and 2D for the Cahn Hilliard (CH) and vector Cahn Hilliard (VCH) equations, based on the Method Of Lines Transpose (MOL$^\text{T}$) formulation. This formulation…

Numerical Analysis · Mathematics 2016-11-15 Matthew Causley , Hana Cho , Andrew Christlieb

Room temperature ionic liquids are attractive to numerous applications and particularly, to renewable energy devices. As solvent free electrolytes, they demonstrate a paramount connection between the material morphology and Coulombic…

Chemical Physics · Physics 2016-03-15 Nir Gavish , Arik Yochelis

The mathematical modeling and numerical simulation of semiconductor-electrolyte systems play important roles in the design of high-performance semiconductor-liquid junction solar cells. In this work, we propose a macroscopic mathematical…

Analysis of PDEs · Mathematics 2015-11-03 Yuan He , Irene M. Gamba , Heung-Chan Lee , Kui Ren

Mechanical effects have mostly been neglected so far in phase field tumour models that are based on a Cahn-Hilliard approach. In this paper we study a macroscopic mechanical model for tumour growth in which cell-cell adhesion effects are…

Analysis of PDEs · Mathematics 2021-01-20 Harald Garcke , Kei Fong Lam , Andrea Signori

Piecewise smooth hybrid systems, involving continuous and discrete variables, are suitable models for describing the multiscale regulatory machinery of the biological cells. In hybrid models, the discrete variables can switch on and off…

Computational Engineering, Finance, and Science · Computer Science 2012-08-21 Vincent Noel , Dima Grigoriev , Sergei Vakulenko , Ovidiu Radulescu

We study the Cahn-Hilliard-Biot model with respect to its mathematical well-posedness. The system models flow through deformable porous media in which the solid material has two phases with distinct material properties. The two phases of…

Analysis of PDEs · Mathematics 2024-10-04 Marvin Fritz

In this paper, we present an efficient numerical algorithm for solving the time-dependent Cahn--Hilliard--Navier--Stokes equations that model the flow of two phases with different densities. The pressure-correction step in the projection…

Numerical Analysis · Mathematics 2020-11-02 Chen Liu , Deep Ray , Christopher Thiele , Lu Lin , Beatrice Riviere

In this paper we propose a time discretization of a system of two parabolic equations describing diffusion-driven atom rearrangement in crystalline matter. The equations express the balances of microforces and microenergy; the two phase…

Analysis of PDEs · Mathematics 2019-02-20 Pierluigi Colli , Gianni Gilardi , Pavel Krejčí , Paolo Podio-Guidugli , Jürgen Sprekels

We perform computer simulations of a Cahn-Hilliard model of phase separation which has dynamical asymmetry between the two coexisting phases. The dynamical asymmetry is incorporated by considering a mobility function which is order…

Soft Condensed Matter · Physics 2009-10-31 Rajeev Ahluwalia

In this paper, the mathematical properties and numerical discretizations of multiphase models that simulate the phase separation of an $N$-component mixture are studied. For the general choice of phase variables, the unisolvent property of…

Mathematical Physics · Physics 2017-05-24 Shuonan Wu , Jinchao Xu

The paper presents a complete research cycle comprising continuum-based modeling, computational framework development, and validation setup to predict phase separation and surface hydrodynamics in lipid bilayer membranes. We starting with…

Numerical Analysis · Mathematics 2025-10-14 Maxim Olshanskii , Annalisa Quaini

We study the systematic numerical approximation of a class of Allen-Cahn type problems modeling the motion of phase interfaces. The common feature of these models is an underlying gradient flow structure which gives rise to a decay of an…

Numerical Analysis · Mathematics 2017-03-09 Anke Böttcher , Herbert Egger

We introduce a nonisothermal phase-field system of Caginalp type that describes tumor growth under hyperthermia. The model couples a possibly viscous Cahn-Hilliard equation, governing the evolution of the healthy and tumor phases, with an…

Analysis of PDEs · Mathematics 2025-10-13 Giulia Cavalleri , Pierluigi Colli , Elisabetta Rocca