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Low-dose CT (LDCT) protocols reduce radiation exposure but increase image noise, compromising diagnostic confidence. Diffusion-based generative models have shown promise for LDCT denoising by learning image priors and performing iterative…

Computer Vision and Pattern Recognition · Computer Science 2025-08-14 Tomás de la Sotta , José M. Saavedra , Héctor Henríquez , Violeta Chang , Aline Xavier

We propose a dual-domain cascade of U-nets (i.e. a "W-net") operating in both the spatial frequency and image domains to enhance low-dose CT (LDCT) images without the need for proprietary x-ray projection data. The central slice theorem…

Image and Video Processing · Electrical Eng. & Systems 2020-05-28 Kevin J. Chung , Roberto Souza , Richard Frayne , Ting-Yim Lee

Background: Limited-angle (LA) dual-energy (DE) cone-beam CT (CBCT) is considered as a potential solution to achieve fast and low-dose DE imaging on current CBCT scanners without hardware modification. However, its clinical implementations…

Low-dose CT (LDCT) reduces radiation exposure but introduces protocol-dependent noise and artifacts that vary across institutions. While federated learning enables collaborative training without centralizing patient data, existing methods…

Image and Video Processing · Electrical Eng. & Systems 2026-03-17 Anas Zafar , Muhammad Waqas , Amgad Muneer , Rukhmini Bandyopadhyay , Jia Wu

The image purification strategy constructs an intermediate distribution with aligned anatomical structures, which effectively corrects the spatial misalignment between real-world ultra-low-dose CT and normal-dose CT images and significantly…

Computer Vision and Pattern Recognition · Computer Science 2026-02-24 Guoliang Gong , Man Yu

Purpose: This study proposes a systematic method for determining the optimal x-ray tube settings/energy windows and fluence for minimal noise and maximum CNR in material density images obtained from DECT scans by fixing the subject size and…

Medical Physics · Physics 2023-08-02 Fatma Terzioglu , Emil Y. Sidky , Jp Phillips , Ingrid Reiser , Guillaume Bal , Xiaochuan Pan

Sparse views X-ray computed tomography has emerged as a contemporary technique to mitigate radiation dose. Because of the reduced number of projection views, traditional reconstruction methods can lead to severe artifacts. Recently,…

Computer Vision and Pattern Recognition · Computer Science 2024-09-04 Liutao Yang , Jiahao Huang , Guang Yang , Daoqiang Zhang

Spectral computed tomography (CT) with photon-counting detectors holds immense potential for material discrimination and tissue characterization. However, under ultra-low-dose conditions, the sharply degraded signal-to-noise ratio (SNR) in…

Computer Vision and Pattern Recognition · Computer Science 2026-02-10 Peng Peng , Xinrui Zhang , Junlin Wang , Lei Li , Shaoyu Wang , Qiegen Liu

Score-based diffusion models have significantly advanced generative deep learning for image processing. Measurement conditioned models have also been applied to inverse problems such as CT reconstruction. However, the conventional approach,…

Medical Physics · Physics 2025-02-24 Matthew Tivnan , Dufan Wu , Quanzheng Li

Limited-Angle Computed Tomography (LACT) is a challenging inverse problem where missing angular projections lead to incomplete sinograms and severe artifacts in the reconstructed images. While recent learning-based methods have demonstrated…

Image and Video Processing · Electrical Eng. & Systems 2025-07-09 Jiaqi Guo , Santiago López-Tapia

Low-dose computed tomography (LDCT) reduces the X-ray radiation but compromises image quality with more noises and artifacts. A plethora of transformer models have been developed recently to improve LDCT image quality. However, the success…

Image and Video Processing · Electrical Eng. & Systems 2022-10-18 Dayang Wang , Yongshun Xu , Shuo Han , Hengyong Yu

Computed tomography and magnetic resonance imaging are two widely used clinical imaging modalities for non-invasive diagnosis. However, both of these modalities come with certain problems. CT uses harmful ionising radiation, and MRI suffers…

Image and Video Processing · Electrical Eng. & Systems 2023-03-03 Philipp Ernst , Soumick Chatterjee , Georg Rose , Oliver Speck , Andreas Nürnberger

Multi-energy CT takes advantage of the non-linearly varying attenuation properties of elemental media with respect to energy, enabling more precise material identification than single-energy CT. The increased precision comes with the cost…

Medical Physics · Physics 2020-02-14 Jussi Toivanen , Alexander Meaney , Samuli Siltanen , Ville Kolehmainen

Low-dose computed tomography (LDCT) reduces radiation exposure but often degrades image quality, potentially compromising diagnostic accuracy. Existing deep learning-based denoising methods focus primarily on pixel-level mappings,…

Image and Video Processing · Electrical Eng. & Systems 2025-07-09 Zhihao Chen , Tao Chen , Chenhui Wang , Qi Gao , Huidong Xie , Chuang Niu , Ge Wang , Hongming Shan

Low-dose emission tomography (ET) plays a crucial role in medical imaging, enabling the acquisition of functional information for various biological processes while minimizing the patient dose. However, the inherent randomness in the photon…

Recent developments in low-field (LF) magnetic resonance imaging (MRI) systems present remarkable opportunities for affordable and widespread MRI access. A robust denoising method to overcome the intrinsic low signal-noise-ratio (SNR)…

Image and Video Processing · Electrical Eng. & Systems 2024-05-01 Zheren Zhu , Azaan Rehman , Xiaozhi Cao , Congyu Liao , Yoo Jin Lee , Michael Ohliger , Hui Xue , Yang Yang

The application of iodinated contrast media (ICM) improves the sensitivity and specificity of computed tomography (CT) for a wide range of clinical indications. However, overdose of ICM can cause problems such as kidney damage and…

Computer Vision and Pattern Recognition · Computer Science 2026-01-29 Genyuan Zhang , Zihao Wang , Zhifan Gao , Lei Xu , Zhen Zhou , Haijun Yu , Jianjia Zhang , Xiujian Liu , Weiwei Zhang , Shaoyu Wang , Huazhu Fu , Fenglin Liu , Weiwen Wu

Organ segmentation in Positron Emission Tomography (PET) plays a vital role in cancer quantification. Low-dose PET (LDPET) provides a safer alternative by reducing radiation exposure. However, the inherent noise and blurred boundaries make…

Tissues and Organs · Quantitative Biology 2025-06-30 Zanting Ye , Xiaolong Niu , Xu Han , Xuanbin Wu , Wantong Lu , Yijun Lu , Hao Sun , Yanchao Huang , Hubing Wu , Lijun Lu

Performing X-ray computed tomography (CT) examinations with less radiation has recently received increasing interest: in medical imaging this means less (potentially harmful) radiation for the patient; in non-destructive testing of…

Medical Physics · Physics 2018-09-25 Dragos Trinca , Eduard Libin

Image denoising is of great importance for medical imaging system, since it can improve image quality for disease diagnosis and downstream image analyses. In a variety of applications, dynamic imaging techniques are utilized to capture the…

Image and Video Processing · Electrical Eng. & Systems 2021-06-24 Junshen Xu , Elfar Adalsteinsson
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