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A low-cost, accurate device to measure and record knee range of motion (ROM) is of the essential need to improve confidence in at-home rehabilitation. It is to reduce hospital stay duration and overall medical cost after Total Knee…

Knee osteoarthritis (OA) is one of the most widespread and burdensome health problems [1-4]. Total knee replacement (TKR) may be offered as treatment for end-stage knee OA. Nevertheless, TKR is an invasive procedure involving prosthesis…

Image and Video Processing · Electrical Eng. & Systems 2025-11-20 Zhisen Hu , Dominic Cullen , David S. Johnson , Aleksei Tiulpin , Timothy F. Cootes , Claudia Lindner

We developed deep learning models for predicting Total Knee Replacement (TKR) need within various time horizons in knee osteoarthritis patients, with a novel capability: the models can perform TKR prediction using a single scan, and…

Image and Video Processing · Electrical Eng. & Systems 2025-03-31 Haresh Rengaraj Rajamohan , Richard Kijowski , Kyunghyun Cho , Cem M. Deniz

Objective: To assess the ability of imaging-based deep learning to predict radiographic patellofemoral osteoarthritis (PFOA) from knee lateral view radiographs. Design: Knee lateral view radiographs were extracted from The Multicenter…

Computer Vision and Pattern Recognition · Computer Science 2021-01-13 Neslihan Bayramoglu , Miika T. Nieminen , Simo Saarakkala

Knee Osteoarthritis (OA) is a common musculoskeletal disorder in the United States. When diagnosed at early stages, lifestyle interventions such as exercise and weight loss can slow OA progression, but at later stages, only an invasive…

Image and Video Processing · Electrical Eng. & Systems 2020-02-26 Aniket A. Tolpadi , Jinhee J. Lee , Valentina Pedoia , Sharmila Majumdar

Radiographic knee alignment (KA) measurement is important for predicting joint health and surgical outcomes after total knee replacement. Traditional methods for KA measurements are manual, time-consuming and require long-leg radiographs.…

Computer Vision and Pattern Recognition · Computer Science 2025-06-24 Zhisen Hu , Dominic Cullen , Peter Thompson , David Johnson , Chang Bian , Aleksei Tiulpin , Timothy Cootes , Claudia Lindner

Total knee arthroplasty (TKA) and total hip arthroplasty (THA) improve symptoms in end-stage osteoarthritis, yet long-term objective characterization of perioperative physical activity trajectories remains limited. We conducted a…

Knee Osteoarthritis (KOA) is a highly prevalent chronic musculoskeletal condition with no currently available treatment. The manifestation of KOA is heterogeneous and prediction of its progression is challenging. Current literature suggests…

Image and Video Processing · Electrical Eng. & Systems 2023-07-04 Egor Panfilov , Simo Saarakkala , Miika T. Nieminen , Aleksei Tiulpin

The recovery of morphologically accurate anatomical images from deformed ones is challenging in ultrasound (US) image acquisition, but crucial to accurate and consistent diagnosis, particularly in the emerging field of computer-assisted…

Image and Video Processing · Electrical Eng. & Systems 2023-08-09 Zhongliang Jiang , Yue Zhou , Dongliang Cao , Nassir Navab

Objective: To establish an automated pipeline for post-processing of quantitative spin-lattice relaxation time constant in the rotating frame ($T_{1\rho}$) imaging of knee articular cartilage. Design: The proposed post-processing pipeline…

Image and Video Processing · Electrical Eng. & Systems 2024-09-20 Junru Zhong , Yongcheng Yao , Fan Xiao , Tim-Yun Michael Ong , Ki-Wai Kevin Ho , Siyue Li , Chaoxing Huang , Queenie Chan , James F. Griffith , Weitian Chen

Individuals who suffer anterior cruciate ligament (ACL) injury are at higher risk of developing knee osteoarthritis (OA) and almost 50% display symptoms 10 to 20 years post injury. Anterior cruciate ligament reconstruction (ACLR) often does…

Computational Engineering, Finance, and Science · Computer Science 2015-08-19 Abhijit Chandra , Oliva Kar , Kuan-Chuen Wu , Michelle Hall , Jason Gillette

Knee osteoarthritis (OA) is the most common musculoskeletal disease without a cure, and current treatment options are limited to symptomatic relief. Prediction of OA progression is a very challenging and timely issue, and it could, if…

Computer Vision and Pattern Recognition · Computer Science 2019-05-07 Aleksei Tiulpin , Stefan Klein , Sita M. A. Bierma-Zeinstra , Jérôme Thevenot , Esa Rahtu , Joyce van Meurs , Edwin H. G. Oei , Simo Saarakkala

Adaptive optics (AO) system performance is improved using post-processing techniques, such as point spread function (PSF) deconvolution. The PSF estimation involves characterization of the different wavefront (WF) error sources in the AO…

Instrumentation and Methods for Astrophysics · Physics 2018-08-29 Florian Ferreira , Eric Gendron , Gérard Rousset , Damien Gratadour

Achilles Tendon Rupture (ATR) is one of the typical soft tissue injuries. Rehabilitation after such a musculoskeletal injury remains a prolonged process with a very variable outcome. Accurately predicting rehabilitation outcome is crucial…

Quantitative Methods · Quantitative Biology 2019-08-14 Charles Hamesse , Ruibo Tu , Paul Ackermann , Hedvig Kjellström , Cheng Zhang

Osteoarthritis (OA) is a common musculoskeletal condition typically diagnosed from radiographic assessment after clinical examination. However, a visual evaluation made by a practitioner suffers from subjectivity and is highly dependent on…

Computer Vision and Pattern Recognition · Computer Science 2017-04-07 Aleksei Tiulpin , Jérôme Thevenot , Esa Rahtu , Simo Saarakkala

For whole-body (WB) kinetic modeling based on a typical PET scanner, a multi-pass multi-bed scanning protocol is necessary given the limited axial field-of-view. Such a protocol introduces loss of early-dynamics in time-activity curves…

Medical Physics · Physics 2024-05-14 Kyung-Nam Lee , Arman Rahmim , Carlos Uribe

Radiotherapy often involves a prolonged treatment period. During this time, patients may experience organ motion due to breathing and other physiological factors. Predicting and modeling this motion before treatment is crucial for ensuring…

Image and Video Processing · Electrical Eng. & Systems 2025-05-20 Yuxiang Lai , Jike Zhong , Vanessa Su , Xiaofeng Yang

Echocardiography is a key imaging modality for cardiac assessment but remains highly operator-dependent, and access to trained sonographers is limited in underserved settings. Teleoperated robotic echocardiography has been proposed as a…

The diagnostic accuracy and subjectivity of existing Knee Osteoarthritis (OA) ordinal grading systems has been a subject of on-going debate and concern. Existing automated solutions are trained to emulate these imperfect systems, whilst…

Machine Learning · Computer Science 2025-05-30 Niamh Belton , Aonghus Lawlor , Kathleen M. Curran

Total knee arthroplasty (TKA) is a common orthopaedic surgery to replace a damaged knee joint with artificial implants. The inaccuracy of achieving the planned implant position can result in the risk of implant component aseptic loosening,…

Robotics · Computer Science 2022-08-09 Shuai Zhang , Liang Zhao , Shoudong Huang , Hua Wang , Qi Luo , Qi Hao
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