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Automatic segmentation of fine-grained brain structures remains a challenging task. Current segmentation methods mainly utilize 2D and 3D deep neural networks. The 2D networks take image slices as input to produce coarse segmentation in…

Computer Vision and Pattern Recognition · Computer Science 2019-05-08 Yuemeng Li , Hangfan Liu , Hongming Li , Yong Fan

Reconstruction of neuroanatomy is a fundamental problem in neuroscience. Stochastic expression of colors in individual cells is a promising tool, although its use in the nervous system has been limited due to various sources of variability…

Neurons and Cognition · Quantitative Biology 2017-01-24 Uygar Sümbül , Douglas Roussien , Fei Chen , Nicholas Barry , Edward S. Boyden , Dawen Cai , John P. Cunningham , Liam Paninski

Recent trends in cell segmentation have shifted towards universal models to handle diverse cell morphologies and imaging modalities. However, for continuously emerging cell types and imaging techniques, these models still require hundreds…

Computer Vision and Pattern Recognition · Computer Science 2024-12-03 Peilin Zhou , Bo Du , Yongchao Xu

We propose an unsupervised image segmentation approach, that combines a variational energy functional and deep convolutional neural networks. The variational part is based on a recent multichannel multiphase Chan-Vese model, which is…

Computer Vision and Pattern Recognition · Computer Science 2023-06-19 Nadja Gruber , Johannes Schwab , Sebastien Court , Elke Gizewski , Markus Haltmeier

In this work, we present a novel background subtraction system that uses a deep Convolutional Neural Network (CNN) to perform the segmentation. With this approach, feature engineering and parameter tuning become unnecessary since the…

Computer Vision and Pattern Recognition · Computer Science 2017-02-07 Mohammadreza Babaee , Duc Tung Dinh , Gerhard Rigoll

Automated segmentation of the vertebral column in Computed Tomography (CT) scans is a prerequisite for pathological assessment and surgical planning. However, state-of-the-art methods, particularly those based on Transformers or large-scale…

Computer Vision and Pattern Recognition · Computer Science 2026-05-21 K S Nithurshen , Saurabh J. Shigwan

Automatic cell segmentation is an essential step in the pipeline of computer-aided diagnosis (CAD), such as the detection and grading of breast cancer. Accurate segmentation of cells can not only assist the pathologists to make a more…

Image and Video Processing · Electrical Eng. & Systems 2020-12-29 Muyi Sun , Zeyi Yao , Guanhong Zhang

Automated semantic segmentation of cell nuclei in microscopic images is crucial for disease diagnosis and tissue microenvironment analysis. Nonetheless, this task presents challenges due to the complexity and heterogeneity of cells. While…

Image and Video Processing · Electrical Eng. & Systems 2023-08-10 Zhuchen Shao , Sourya Sengupta , Hua Li , Mark A. Anastasio

In recent years, several unsupervised cell segmentation methods have been presented, trying to omit the requirement of laborious pixel-level annotations for the training of a cell segmentation model. Most if not all of these methods handle…

Computer Vision and Pattern Recognition · Computer Science 2023-12-04 Mehdi Naouar , Gabriel Kalweit , Anusha Klett , Yannick Vogt , Paula Silvestrini , Diana Laura Infante Ramirez , Roland Mertelsmann , Joschka Boedecker , Maria Kalweit

Deep convolutional neural networks (CNNs) have been immensely successful in many high-level computer vision tasks given large labeled datasets. However, for video semantic object segmentation, a domain where labels are scarce, effectively…

Computer Vision and Pattern Recognition · Computer Science 2016-06-08 Huiling Wang , Tapani Raiko , Lasse Lensu , Tinghuai Wang , Juha Karhunen

Skin cancer segmentation poses a significant challenge in medical image analysis. Numerous existing solutions, predominantly CNN-based, face issues related to a lack of global contextual understanding. Alternatively, some approaches resort…

Computer Vision and Pattern Recognition · Computer Science 2024-09-06 Shehan Perera , Yunus Erzurumlu , Deepak Gulati , Alper Yilmaz

Image segmentation, the process of partitioning an image into meaningful regions, plays a pivotal role in computer vision and medical imaging applications. Unsupervised segmentation, particularly in the absence of labeled data, remains a…

Computer Vision and Pattern Recognition · Computer Science 2024-05-13 Kovvuri Sai Gopal Reddy , Bodduluri Saran , A. Mudit Adityaja , Saurabh J. Shigwan , Nitin Kumar

It is well accepted that image segmentation can benefit from utilizing multilevel cues. The paper focuses on utilizing the FCNN-based dense semantic predictions in the bottom-up image segmentation, arguing to take semantic cues into account…

Computer Vision and Pattern Recognition · Computer Science 2016-06-07 Qiyang Zhao , Lewis D Griffin

Automated histopathological image analysis plays a vital role in computer-aided diagnosis of various diseases. Among developed algorithms, deep learning-based approaches have demonstrated excellent performance in multiple tasks, including…

Computer Vision and Pattern Recognition · Computer Science 2025-10-24 Nima Torbati , Anastasia Meshcheryakova , Ramona Woitek , Diana Mechtcheriakova , Amirreza Mahbod

Though performed almost effortlessly by humans, segmenting 2D gray-scale or color images into respective regions of interest (e.g.~background, objects, or portions of objects) constitutes one of the greatest challenges in science and…

Computer Vision and Pattern Recognition · Computer Science 2023-08-23 Alexandre Benatti , Luciano da F. Costa

Segmentation of white matter lesions and deep grey matter structures is an important task in the quantification of magnetic resonance imaging in multiple sclerosis. In this paper we explore segmentation solutions based on convolutional…

Accurate, real-time segmentation of vessel structures in ultrasound image sequences can aid in the measurement of lumen diameters and assessment of vascular diseases. This, however, remains a challenging task, particularly for extremely…

Image and Video Processing · Electrical Eng. & Systems 2021-11-05 Baichuan Jiang , Alvin Chen , Shyam Bharat , Mingxin Zheng

In recent years, 3D convolutional neural networks have become the dominant approach for volumetric medical image segmentation. However, compared to their 2D counterparts, 3D networks introduce substantially more training parameters and…

Image and Video Processing · Electrical Eng. & Systems 2022-06-01 Yuan Wang , Laura Blackie , Irene Miguel-Aliaga , Wenjia Bai

Cellular Electron Cryo-Tomography (CECT) is a powerful imaging technique for the 3D visualization of cellular structure and organization at submolecular resolution. It enables analyzing the native structures of macromolecular complexes and…

Quantitative Methods · Quantitative Biology 2018-05-16 Chang Liu , Xiangrui Zeng , Ruogu Lin , Xiaodan Liang , Zachary Freyberg , Eric Xing , Min Xu

Convolutional neural networks (CNNs) are the current state-of-the-art meta-algorithm for volumetric segmentation of medical data, for example, to localize COVID-19 infected tissue on computer tomography scans or the detection of tumour…

Image and Video Processing · Electrical Eng. & Systems 2021-10-22 Christoph Reich , Tim Prangemeier , Özdemir Cetin , Heinz Koeppl