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Sequence discovery tools play a central role in several fields of computational biology. In the framework of Transcription Factor binding studies, motif finding algorithms of increasingly high performance are required to process the big…
The observation that some subgraphs, called motifs, appear more often in real networks than in their randomized counterparts has attracted much attention in the scientific community. In the prevalent approach the detection of motifs is…
Recent genomic and bioinformatic advances have motivated the development of numerous random network models purporting to describe graphs of biological, technological, and sociological origin. The success of a model has been evaluated by how…
Investigating the frequency and distribution of small subgraphs with a few nodes/edges, i.e., motifs, is an effective analysis method for static networks. Motif-driven analysis is also useful for temporal networks where the spectrum of…
With the rise of social networks, information on the internet is no longer solely organized by web pages. Rather, content is generated and shared among users and organized around their social relations on social networks. This presents new…
We introduce a method to convert an ensemble of sequences of symbols into a weighted directed network whose nodes are motifs, while the directed links and their weights are defined from statistically significant co-occurences of two motifs…
Network motifs can capture basic interaction patterns and inform the functional properties of networks. However, real-world complex systems often have multiple types of relationships, which cannot be represented by a monolayer network. The…
Discrete dynamic models are a powerful tool for the understanding and modeling of large biological networks. Although a lot of progress has been made in developing analysis tools for these models, there is still a need to find approaches…
Graphs are now ubiquitous in almost every field of research. Recently, new research areas devoted to the analysis of graphs and data associated to their vertices have emerged. Focusing on dynamical processes, we propose a fast, robust and…
Patterns that appear rarely or unusually in the data can be defined as outlier patterns. The basic idea behind detecting outlier patterns is comparison of their relative frequencies with frequent patterns. Their frequencies of appearance…
A subgraph is constructed by using a subset of vertices and edges of a given graph. There exist many graph properties that are hereditary for subgraphs. Hence, researchers from different communities have paid a great deal of attention in…
Motifs are patterns of subgraphs of complex networks. We studied the impact of such patterns of connectivity on the level of correlated, or synchronized, spiking activity among pairs of cells in a recurrent network model of integrate and…
Human trajectory anomaly detection has become increasingly important across a wide range of applications, including security surveillance and public health. However, existing trajectory anomaly detection methods are primarily focused on…
An important task in network analysis is the detection of anomalous events in a network time series. These events could merely be times of interest in the network timeline or they could be examples of malicious activity or network…
Hierarchies permeate the structure of real networks, whose nodes can be ranked according to different features. However, networks are far from tree-like structures and the detection of hierarchical ordering remains a challenge, hindered by…
Anomaly detection is a relevant problem in the area of data analysis. In networked systems, where individual entities interact in pairs, anomalies are observed when pattern of interactions deviates from patterns considered regular. Properly…
In real-world scenarios, large graphs represent relationships among entities in complex systems. Mining these large graphs often containing millions of nodes and edges helps uncover structural patterns and meaningful insights. Dividing a…
The identification and counting of small graph patterns, called network motifs, is a fundamental primitive in the analysis of networks, with application in various domains, from social networks to neuroscience. Several techniques have been…
Many real-world applications give rise to large heterogeneous networks where nodes and edges can be of any arbitrary type (e.g., user, web page, location). Special cases of such heterogeneous graphs include homogeneous graphs, bipartite,…
Recently, interest has grown in exploring the hypothesis that neural activity conveys information through precise spiking motifs. To investigate this phenomenon, various algorithms have been proposed to detect such motifs in Single Unit…