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Evidential Deep Learning (EDL) has emerged as an efficient, sampling-free strategy for uncertainty estimation. A series of EDL variants have been proposed to address specific limitations of the original framework, achieving notable success.…

Machine Learning · Computer Science 2026-05-26 Yuanye Liu , Yibo Gao , Yuanyang Chen , Xiahai Zhuang

Entities lie in the heart of biomedical natural language understanding, and the biomedical entity linking (EL) task remains challenging due to the fine-grained and diversiform concept names. Generative methods achieve remarkable…

Computation and Language · Computer Science 2022-05-24 Hongyi Yuan , Zheng Yuan , Sheng Yu

Molecular property prediction (e.g., energy) is an essential problem in chemistry and biology. Unfortunately, many supervised learning methods usually suffer from the problem of scarce labeled molecules in the chemical space, where such…

Machine Learning · Computer Science 2020-07-08 Zhongkai Hao , Chengqiang Lu , Zheyuan Hu , Hao Wang , Zhenya Huang , Qi Liu , Enhong Chen , Cheekong Lee

Despite the recent progresses, particularly in developing Language Models, there are fundamental challenges and unanswered questions about how such models can continually learn/memorize, self-improve, and find effective solutions. In this…

Machine Learning · Computer Science 2026-01-01 Ali Behrouz , Meisam Razaviyayn , Peilin Zhong , Vahab Mirrokni

Expectation maximisation (EM) is an unsupervised learning method for estimating the parameters of a finite mixture distribution. It works by introducing "hidden" or "latent" variables via Baum's auxiliary function $Q$ that allow the joint…

Machine Learning · Computer Science 2022-05-19 Graham W. Pulford

Understanding how the brain encodes stimuli has been a fundamental problem in computational neuroscience. Insights into this problem have led to the design and development of artificial neural networks that learn representations by…

Neurons and Cognition · Quantitative Biology 2025-12-04 Shubham Choudhary , Paul Masset , Demba Ba

Recently, label distribution learning (LDL) has drawn much attention in machine learning, where LDL model is learned from labelel instances. Different from single-label and multi-label annotations, label distributions describe the instance…

Machine Learning · Computer Science 2021-04-13 Qinghai Zheng , Jihua Zhu , Haoyu Tang , Xinyuan Liu , Zhongyu Li , Huimin Lu

The ever-increasing size of modern data sets combined with the difficulty of obtaining label information has made semi-supervised learning one of the problems of significant practical importance in modern data analysis. We revisit the…

Machine Learning · Computer Science 2014-11-06 Diederik P. Kingma , Danilo J. Rezende , Shakir Mohamed , Max Welling

Deep neural networks (DNNs) excel on fixed datasets but struggle with incremental and shifting data in real-world scenarios. Continual learning addresses this challenge by allowing models to learn from new data while retaining previously…

Computer Vision and Pattern Recognition · Computer Science 2025-06-10 Lu Yu , Zhe Tao , Dipam Goswami , Hantao Yao , Bartłomiej Twardowski , Joost Van de Weijer , Changsheng Xu

Large language model pretraining is compute-intensive, yet many tokens contribute marginally to learning, resulting in inefficiency. We introduce Efficient Selective Language Modeling (ESLM), a risk-aware algorithm that improves training…

Machine Learning · Computer Science 2025-05-27 Melis Ilayda Bal , Volkan Cevher , Michael Muehlebach

The classification of amino acids and their sequence analysis plays a vital role in life sciences and is a challenging task. This article uses and compares state-of-the-art deep learning models like convolution neural networks (CNN), long…

Biomolecules · Quantitative Biology 2022-07-26 Sarwar Khan , Faisal Ghaffar , Imad Ali , Qazi Mazhar

Although zero-shot learning (ZSL) has an inferential capability of recognizing new classes that have never been seen before, it always faces two fundamental challenges of the cross modality and crossdomain challenges. In order to alleviate…

Computer Vision and Pattern Recognition · Computer Science 2021-01-26 Cheng Xie , Hongxin Xiang , Ting Zeng , Yun Yang , Beibei Yu , Qing Liu

The recent advance in deep generative models outlines a promising perspective in the realm of Zero-Shot Learning (ZSL). Most generative ZSL methods use category semantic attributes plus a Gaussian noise to generate visual features. After…

Computer Vision and Pattern Recognition · Computer Science 2021-12-24 Xiaojie Zhao , Yuming Shen , Shidong Wang , Haofeng Zhang

Semi-supervised learning aims to learn prediction models from both labeled and unlabeled samples. There has been extensive research in this area. Among existing work, generative mixture models with Expectation-Maximization (EM) is a popular…

Machine Learning · Computer Science 2020-08-31 Wenchong He , Zhe Jiang

Continual learning is essential for medical image classification systems to adapt to dynamically evolving clinical environments. The integration of multimodal information can significantly enhance continual learning of image classes.…

Computer Vision and Pattern Recognition · Computer Science 2025-08-06 Jiantao Tan , Peixian Ma , Kanghao Chen , Zhiming Dai , Ruixuan Wang

Drug discovery using deep learning has attracted a lot of attention of late as it has obvious advantages like higher efficiency, less manual guessing and faster process time. In this paper, we present a novel neural network for generating…

Biomolecules · Quantitative Biology 2021-10-08 Abhinav Sagar

We introduce a generative learning framework to model high-dimensional parametric systems using gradient guidance and virtual observations. We consider systems described by Partial Differential Equations (PDEs) discretized with structured…

Machine Learning · Computer Science 2024-08-02 Han Gao , Sebastian Kaltenbach , Petros Koumoutsakos

Multi-task learning for molecular property prediction is becoming increasingly important in drug discovery. However, in contrast to other domains, the performance of multi-task learning in drug discovery is still not satisfying as the…

Biomolecules · Quantitative Biology 2022-10-07 Shengchao Liu , Meng Qu , Zuobai Zhang , Huiyu Cai , Jian Tang

Graphs and networks are a key research tool for a variety of science fields, most notably chemistry, biology, engineering and social sciences. Modeling and generation of graphs with efficient sampling is a key challenge for graphs. In…

Machine Learning · Computer Science 2019-09-26 Ruud van Deursen , Guillaume Godin

Automatic histopathology image segmentation is crucial to disease analysis. Limited available labeled data hinders the generalizability of trained models under the fully supervised setting. Semi-supervised learning (SSL) based on generative…

Computer Vision and Pattern Recognition · Computer Science 2020-12-18 Hongxiao Wang , Hao Zheng , Jianxu Chen , Lin Yang , Yizhe Zhang , Danny Z. Chen