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Many intracellular processes continue to oscillate during the cell cycle. Although it is not well-understood how they are affected by discontinuities in the cellular environment, the general assumption is that oscillations remain robust…

Molecular Networks · Quantitative Biology 2014-09-25 David S. Tourigny

Mechanical oscillations are important for many cellular processes, e.g. the beating of cilia and flagella or the sensation of sound by hair cells. These dynamic states originate from spontaneous oscillations of molecular motors. A…

Biological Physics · Physics 2009-01-29 Stefan Gunther , Karsten Kruse

The vertex model is widely used to describe the dynamics of epithelial tissues, because of its simplicity and versatility and the direct inclusion of biophysical parameters. Here, it is shown that quite generally, when cells modify their…

Soft Condensed Matter · Physics 2020-11-25 Fernanda Perez-Verdugo , Jean-Francois Joanny , Rodrigo Soto

Undoped and strongly photoexcited semiconductor superlattices with field-dependent recombination behave as excitable or oscillatory media with spatially discrete nonlinear convection and diffusion. Infinitely long, dc-current-biased…

Mesoscale and Nanoscale Physics · Physics 2015-05-30 J. I. Arana , L. L. Bonilla , H. T. Grahn

Experimental evidence shows that there is a feedback between cell shape and cell motion. How this feedback impacts the collective behavior of dense cell monolayers remains an open question. We investigate the effect of a feedback that tends…

Research on magnetic particles dispersed in a fluid medium, actuated by a rotating magnetic field, is becoming increasingly active for both lab-on-chip and bio-sensing applications. In this study, we experimentally investigate the behaviour…

Soft Condensed Matter · Physics 2020-02-25 Abdelqader Zaben , Guntars Kitenbergs , Andrejs Cēbers

Understanding cellular response to mechanical forces is immensely important for a plethora of biological processes. Focal adhesions are multi-molecular protein assemblies that connect the cell to the extracellular matrix and play a pivotal…

Biological Physics · Physics 2019-10-25 Rumi De

Many microorganisms, with phytoplankton and zooplankton as prominent examples, display phototactic behaviour, that is, the ability to perform directed motion within a light gradient. Here we experimentally demonstrate that sensing of light…

Soft Condensed Matter · Physics 2016-10-03 Celia Lozano , Borge ten Hagen , Hartmut Löwen , Clemens Bechinger

In the cellular phenomena of cytoplasmic streaming, molecular motors carrying cargo along a network of microtubules entrain the surrounding fluid. The piconewton forces produced by individual motors are sufficient to deform long…

Soft Condensed Matter · Physics 2021-01-20 David B. Stein , Gabriele De Canio , Eric Lauga , Michael J. Shelley , Raymond E. Goldstein

A biophysical model of epimorphic regeneration based on a continuum percolation process of fully penetrable disks in two dimensions is proposed. All cells within a randomly chosen disk of the regenerating organism are assumed to receive a…

Biological Physics · Physics 2023-11-06 Vladimir García-Morales

Confluent cell monolayers and epithelia tissues show remarkable patterns and correlations in structural arrangements and actively-driven collective flows. We simulate these properties using multiphase field models. The models are based on…

Soft Condensed Matter · Physics 2021-12-08 Dennis Wenzel , Axel Voigt

Recent research has shown that motile cells can adapt their mode of propulsion to the mechanical properties of the environment in which they find themselves--crawling in some environments while swimming in others. The latter can involve…

Biological Physics · Physics 2018-05-24 Hao Wu , Marco Avila Ponce de Leon , Hans G. Othmer

Migratory and tissue resident cells exhibit highly branched morphologies to perform their function and to adapt to the microenvironment. Immune cells, for example, display transient branched shapes while exploring the surrounding tissues.…

Biological Physics · Physics 2024-04-02 Jiayi Liu , Javier Boix-Campos , Jonathan E. Ron , Johan M. Kux , Nir S. Gov , Pablo J. Sáez

Chemo-mechanical waves on active deformable surfaces are a key component for many vital cellular functions. In particular, these waves play a major role in force generation and long-range signal transmission in cells that dynamically change…

In order to grasp the features arising from cellular discreteness and individuality, in large parts of cell tissue modelling agent-based models are favoured. The subclass of off-lattice models allows for a physical motivation of the…

Biological Physics · Physics 2007-06-21 Gernot Schaller , Michael Meyer-Hermann

Since a long time the application of small electric potentials on biological membranes (iontophoresis) proved enabling control and improvement of transdermal delivery of substances across this barrier. In spite of a large experimental data,…

Tissues and Organs · Quantitative Biology 2019-05-07 Neila Machado , Clarissa Callegaro , Marcelo Augusto Christoffolete , Herculano Martinho

Gyrotactic algae are bottom heavy, motile cells whose swimming direction is determined by a balance between a buoyancy torque directing them upwards and fluid velocity gradients. Gyrotaxis has, in recent years, become a paradigmatic model…

Chaotic Dynamics · Physics 2019-03-25 Massimo Cencini , Guido Boffetta , Matteo Borgnino , Filippo De Lillo

Biological cells are able to generate intricate structures and respond to external stimuli, sculpting their membrane from within. Simplified biomimetic systems can aid in understanding the principles which govern these shape changes and…

Cell walls define a cell shape in bacteria. They are rigid to resist large internal pressures, but remarkably plastic to adapt to a wide range of external forces and geometric constraints. Currently, it is unknown how bacteria maintain…

Soft Condensed Matter · Physics 2014-05-01 Ariel Amir , Farinaz Babaeipour , Dustin B. McIntosh , David R. Nelson , Suckjoon Jun

Magnetotactic bacteria moving on circular orbits form hydrodynamically bound states. When close to a surface and with the tilting of the field in a direction close to the perpendicular to this surface these swarms move perpendicularly to…

Soft Condensed Matter · Physics 2017-07-11 K. Bente , G. Kitenbergs , D. Kriman , K. Erglis , M. Belovs , D. Faivre , A. Cebers
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