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This paper considers the design of observational longitudinal studies with a continuous response and a binary time-invariant exposure, where, typically, the exposure is unbalanced, the mean response in the two groups differs at baseline and…

Methodology · Statistics 2022-09-27 Xavier Basagana , Donna Spiegelman

A two-stage adaptive optimal design is an attractive option for increasing the efficiency of clinical trials. In these designs, based on interim data, the locally optimal dose is chosen for further exploration, which induces dependencies…

Methodology · Statistics 2019-05-24 Zhantao Lin , Nancy Flournoy , William F. Rosenberger

Olfactory receptor usage is highly heterogeneous, with some receptor types being orders of magnitude more abundant than others. We propose an explanation for this striking fact: the receptor distribution is tuned to maximally represent…

Neurons and Cognition · Quantitative Biology 2019-01-23 Tiberiu Tesileanu , Simona Cocco , Remi Monasson , Vijay Balasubramanian

The Regression Discontinuity (RD) design is a quasi-experimental design which emulates a randomised study by exploiting situations where treatment is assigned according to a continuous variable as is common in many drug treatment…

Methodology · Statistics 2016-07-28 Sara Geneletti , Federico Ricciardi , Aidan O'Keeffe , Gianluca Baio

We study efficiency improvements in randomized experiments for estimating a vector of potential outcome means using regression adjustment (RA) when there are more than two treatment levels. We show that linear RA which estimates separate…

Econometrics · Economics 2025-01-13 Akanksha Negi , Jeffrey M. Wooldridge

We introduce Uncertain Natural Language Inference (UNLI), a refinement of Natural Language Inference (NLI) that shifts away from categorical labels, targeting instead the direct prediction of subjective probability assessments. We…

Computation and Language · Computer Science 2020-05-06 Tongfei Chen , Zhengping Jiang , Adam Poliak , Keisuke Sakaguchi , Benjamin Van Durme

A factor model with a break in its factor loadings is observationally equivalent to a model without changes in the loadings but a change in the variance of its factors. This effectively transforms a structural change problem of high…

Econometrics · Economics 2023-12-06 Jushan Bai , Jiangtao Duan , Xu Han

Robust Bayesian analysis has been mainly devoted to detecting and measuring robustness w.r.t. the prior distribution. Many contributions in the literature aim to define suitable classes of priors which allow the computation of variations of…

Statistics Theory · Mathematics 2025-09-04 Antonio Di Noia , Fabrizio Ruggeri , Antonietta Mira

Inverse reinforcement learning (IRL) aims to infer an agent's preferences (represented as a reward function $R$) from their behaviour (represented as a policy $\pi$). To do this, we need a behavioural model of how $\pi$ relates to $R$. In…

Machine Learning · Computer Science 2024-03-12 Joar Skalse , Alessandro Abate

Ordered categorical data frequently arise in the analysis of biomedical, agricultural, and social sciences data. The logistic regression model is attractive in analyzing ordered categorical data because of its use in interpretation of a…

Applications · Statistics 2016-01-08 Ali Reza Fotouhi , Theresa Mulder

Practitioners commonly align large language models using pairwise preferences, i.e., given labels of the type response A is preferred to response B for a given input. Perhaps less commonly, methods have also been developed for binary…

Computation and Language · Computer Science 2024-04-24 Jing Xu , Andrew Lee , Sainbayar Sukhbaatar , Jason Weston

Guessing random additive noise decoding (GRAND) is a recently proposed decoding paradigm particularly suitable for codes with short length and high rate. Among its variants, ordered reliability bits GRAND (ORBGRAND) exploits soft…

Information Theory · Computer Science 2024-04-30 Li Wan , Wenyi Zhang

The real-world data is often susceptible to label noise, which might constrict the effectiveness of the existing state of the art algorithms for ordinal regression. Existing works on ordinal regression do not take label noise into account.…

Machine Learning · Computer Science 2020-01-28 Bhanu Garg , Naresh Manwani

Instrumental variable methods allow for inference about the treatment effect by controlling for unmeasured confounding in randomized experiments with noncompliance. However, many studies do not consider the observed compliance behavior in…

Methodology · Statistics 2020-06-15 Kwonsang Lee , Bhaswar B. Bhattacharya , Jing Qin , Dylan S. Small

We consider a linear regression model with complex-valued response and predictors from a compact and connected Lie group. The regression model is formulated in terms of eigenfunctions of the Laplace-Beltrami operator on the Lie group. We…

Statistics Theory · Mathematics 2024-10-02 Somnath Chakraborty , Holger Dette , Martin Kroll

Estimating the ratio of two probability densities from a finite number of observations is a central machine learning problem. A common approach is to construct estimators using binary classifiers that distinguish observations from the two…

Machine Learning · Computer Science 2025-01-28 Werner Zellinger

Measurement error in observational datasets can lead to systematic bias in inferences based on these datasets. As studies based on observational data are increasingly used to inform decisions with real-world impact, it is critical that we…

Machine Learning · Statistics 2019-01-29 Roy Adams , Yuelong Ji , Xiaobin Wang , Suchi Saria

The classical tests in the instrumental variable model can behave arbitrarily if the data is contaminated. For instance, one outlying observation can be enough to change the outcome of a test. We develop a framework to construct testing…

Econometrics · Economics 2024-03-26 Jens Klooster , Mikhail Zhelonkin

Measurement error arises through a variety of mechanisms. A rich literature exists on the bias introduced by covariate measurement error and on methods of analysis to address this bias. By comparison, less attention has been given to errors…

Methodology · Statistics 2018-11-27 Pamela Shaw , Jiwei He , Bryan Shepherd

Online Learning to Rank (OL2R) eliminates the need of explicit relevance annotation by directly optimizing the rankers from their interactions with users. However, the required exploration drives it away from successful practices in offline…

Machine Learning · Computer Science 2021-06-03 Yiling Jia , Huazheng Wang , Stephen Guo , Hongning Wang