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Related papers: Vibrational Control of Cluster Synchronization: Co…

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Deep brain stimulation (DBS) is an established method for treating pathological conditions such as Parkinson's disease, dystonia, Tourette syndrome, and essential tremor. While the precise mechanisms which underly the effectiveness of DBS…

Dynamical Systems · Mathematics 2020-07-07 Daniel Kuelbs , Jacob Dunefsky , Bharat Monga , Jeff Moehlis

Cluster synchronization is of paramount importance for the normal functioning of numerous technological and natural systems. Deviations from normal cluster synchronization patterns are closely associated with various malfunctions, such as…

Optimization and Control · Mathematics 2023-08-15 Yuzhen Qin , Alberto Maria Nobili , Danielle S. Bassett , Fabio Pasqualetti

Cluster synchronization is of great importance for the normal functioning of numerous technological and natural systems. Deviations from normal cluster synchronization patterns are closely associated with various malfunctions, such as…

Systems and Control · Electrical Eng. & Systems 2025-09-23 Yuzhen Qin , Alberto Maria Nobili , Danielle S. Bassett , Fabio Pasqualetti

Brain networks typically exhibit characteristic synchronization patterns where several synchronized clusters coexist. On the other hand, neurological disorders are considered to be related to pathological synchronization such as excessive…

Systems and Control · Electrical Eng. & Systems 2025-07-31 Ryota Kokubo , Rui Kato , Hideaki Ishii

Deep brain stimulation (DBS) is an advanced surgical treatment for the symptoms of Parkinson's disease (PD), involving electrical stimulation of neurons within the basal ganglia region of the brain. DBS is traditionally delivered in an…

Systems and Control · Electrical Eng. & Systems 2025-06-19 Cédric Join , Jakub Orłowski , Antoine Chaillet , Madeleine Lowery , Hugues Mounier , Michel Fliess

Deep Brain Stimulation (DBS) is an established and powerful treatment method in various neurological disorders. It involves chronically delivering electrical pulses to a certain stimulation target in the brain in order to alleviate the…

Systems and Control · Electrical Eng. & Systems 2023-10-03 Anna Franziska Frigge , Alexander Medvedev , Elena Jiltsova , Dag Nyholm

Synchronization is an ubiquitous phenomenon in dynamical systems of networked oscillators. While it is often a goal to achieve, in some context one would like to decrease it, e.g., although synchronization is essential to the good…

Dynamical Systems · Mathematics 2025-04-07 Martin Moriamé , Timoteo Carletti

Essential Tremor is the most common neurological movement disorder. This progressive disease causes uncontrollable rhythmic motions -most often affecting the patient's dominant upper extremity- that occur during volitional movement and make…

Neurons and Cognition · Quantitative Biology 2017-06-02 Jeffrey A. Herron , Margaret C. Thompson , Timothy Brown , Howard J. Chizeck , Jeffrey G. Ojemann , Andrew L. Ko

Models of the cortico-basal ganglia network and volume conductor models of the brain can provide insight into the mechanisms of action of deep brain stimulation (DBS). In this study, the coupling of a network model, under parkinsonian…

Neurons and Cognition · Quantitative Biology 2017-05-31 Christian Schmidt , Eleanor Dunn , Madeleine Lowery , Ursula van Rienen

Suppression of excessively synchronous beta-band oscillatory activity in the brain is believed to suppress hypokinetic motor symptoms of Parkinson's disease. Recently, a lot of interest has been devoted to desynchronizing delayed feedback…

Neurons and Cognition · Quantitative Biology 2013-03-05 Andrey Dovzhenok , Choongseok Park , Robert M. Worth , Leonid L. Rubchinsky

Deep Brain Stimulation (DBS) is a therapy widely used for treating the symptoms of neurological disorders. Electrical pulses are chronically delivered in DBS to a disease-specific brain target via a surgically implanted electrode. The…

Systems and Control · Electrical Eng. & Systems 2024-10-24 Anna Franziska Frigge , Elena Jiltsova , Fredrik Olsson , Dag Nyholm , Alexander Medvedev

Synchrony of neuronal ensembles is believed to facilitate information exchange among cortical regions in the human brain. Recently, it has been observed that distant brain areas which are not directly connected by neural links also…

Chaotic Dynamics · Physics 2021-02-23 Yuzhen Qin , Yu Kawano , Ming Cao

In this paper, we propose a framework to control brain-wide functional connectivity by selectively acting on the brain's structure and parameters. Functional connectivity, which measures the degree of correlation between neural activities…

Systems and Control · Computer Science 2020-03-17 Tommaso Menara , Giacomo Baggio , Danielle S. Bassett , Fabio Pasqualetti

In this paper we study cluster synchronization in networks of oscillators with heterogenous Kuramoto dynamics, where multiple groups of oscillators with identical phases coexist in a connected network. Cluster synchronization is at the…

Optimization and Control · Mathematics 2020-05-06 Tommaso Menara , Giacomo Baggio , Danielle S. Bassett , Fabio Pasqualetti

Deep brain stimulation (DBS) has the potential to improve the quality of life of people with a variety of neurological diseases. A key challenge in DBS is in the placement of a stimulation electrode in the anatomical location that maximizes…

Computer Vision and Pattern Recognition · Computer Science 2018-11-27 Camilo Bermudez , William Rodriguez , Yuankai Huo , Allison E. Hainline , Rui Li , Robert Shults , Pierre D. DHaese , Peter E. Konrad , Benoit M. Dawant , Bennett A. Landman

Deep brain stimulation (DBS) can alleviate the movement disorders like Parkinson's disease (PD). Indeed, it is known that aberrant beta (13-30Hz)oscillations and the loss of dopaminergic neurons in the basal ganglia-thalamus (BGTH) and…

Neurons and Cognition · Quantitative Biology 2021-12-07 Hina Shaheen , Roderick Melnik

Deep Brain Stimulation (DBS) is a well-established neurosurgical treatment aiming at symptom alleviation in a range of neurological and psychiatric diseases. Computational models of DBS are widely used to investigate the effects of…

Systems and Control · Electrical Eng. & Systems 2025-11-17 Anna Franziska Frigge , Alexander Medvedev

We present a nonlinear data-driven Model Predictive Control (MPC) algorithm for deep brain stimulation (DBS) for the treatment of Parkinson's disease (PD). Although DBS is typically implemented in open-loop, closed-loop DBS (CLDBS) uses the…

Optimization and Control · Mathematics 2025-09-09 Sebastian Steffen , Mark Cannon

Based on recent advances in fibration symmetry theory, we investigate how structural symmetries influence synchronization in systems with higher-order interactions (HOI). Using bipartite graph representations, we identify a node partition…

Dynamical Systems · Mathematics 2026-01-12 Margherita Bertè , Tommaso Gili

The stability of complex networks, from power grids to biological systems, is crucial for their proper functioning. It is thus important to control such systems to maintain or restore their stability. Traditional approaches rely on…

Optimization and Control · Mathematics 2025-09-23 Yuzhen Qin , Fabio Pasqualetti , Danielle S. Bassett , Marcel van Gerven
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