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Prediction models are used amongst others to inform medical decisions on interventions. Typically, individuals with high risks of adverse outcomes are advised to undergo an intervention while those at low risk are advised to refrain from…

Causal inference is a critical research topic across many domains, such as statistics, computer science, education, public policy and economics, for decades. Nowadays, estimating causal effect from observational data has become an appealing…

Methodology · Statistics 2020-02-10 Liuyi Yao , Zhixuan Chu , Sheng Li , Yaliang Li , Jing Gao , Aidong Zhang

Risk of suicide attempt varies over time. Understanding the importance of risk factors measured at a mental health visit can help clinicians evaluate future risk and provide appropriate care during the visit. In prediction settings where…

A systematic review identifies and collates various clinical studies and compares data elements and results in order to provide an evidence based answer for a particular clinical question. The process is manual and involves lot of time. A…

Information Retrieval · Computer Science 2016-06-22 Tanmay Basu , Shraman Kumar , Abhishek Kalyan , Priyanka Jayaswal , Pawan Goyal , Stephen Pettifer , Siddhartha R. Jonnalagadda

Dropout is common in clinical studies, with up to half of patients leaving early due to side effects or other reasons. When dropout is informative (i.e., dependent on survival time), it introduces censoring bias, because of which treatment…

Machine Learning · Computer Science 2026-05-12 Yuxin Wang , Dennis Frauen , Jonas Schweisthal , Maresa Schröder , Stefan Feuerriegel

The IMPRESSIONS section of a radiology report about an imaging study is a summary of the radiologist's reasoning and conclusions, and it also aids the referring physician in confirming or excluding certain diagnoses. A cascade of tasks are…

Computation and Language · Computer Science 2022-05-03 Sanjeev Kumar Karn , Ning Liu , Hinrich Schuetze , Oladimeji Farri

We study the problem of efficiently estimating the effect of an intervention on a single variable (atomic interventions) using observational samples in a causal Bayesian network. Our goal is to give algorithms that are efficient in both…

Machine Learning · Computer Science 2020-08-07 Arnab Bhattacharyya , Sutanu Gayen , Saravanan Kandasamy , Ashwin Maran , N. V. Vinodchandran

Familiar statistical tests and estimates are obtained by the direct observation of cases of interest: a clinical trial of a new drug, for instance, will compare the drug's effects on a relevant set of patients and controls. Sometimes,…

Methodology · Statistics 2010-12-09 Bradley Efron

Predictive risk scores estimating probabilities for a binary outcome on the basis of observed covariates are common across the sciences. They are frequently developed with the intent of avoiding the outcome in question by intervening in…

Methodology · Statistics 2022-08-26 James Liley

Accurately quantifying uncertainty of individual treatment effects (ITEs) across multiple decision points is crucial for personalized decision-making in fields such as healthcare, finance, education, and online marketplaces. Previous work…

Methodology · Statistics 2025-12-10 Swaraj Bose , Walter Dempsey

Proximal causal inference provides a framework for estimating the average treatment effect (ATE) in the presence of unmeasured confounding by leveraging outcome and treatment proxies. Identification in this framework relies on the existence…

Methodology · Statistics 2025-12-29 Chunrong Ai , Jiawei Shan

Systematic reviews in medicine play a critical role in evidence-based decision-making by aggregating findings from multiple studies. A central bottleneck in automating this process is extracting numeric evidence and determining study-level…

Artificial Intelligence · Computer Science 2026-01-26 Massimiliano Pronesti , Michela Lorandi , Paul Flanagan , Oisin Redmond , Anya Belz , Yufang Hou

Large language models (LLMs) are widely explored for reasoning-intensive research tasks, yet resources for testing whether they can infer scientific conclusions from structured biomedical evidence remain limited. We introduce…

Computation and Language · Computer Science 2026-04-09 Weiyue Li , Ruizhi Qian , Yi Li , Yongce Li , Yunfan Long , Jiahui Cai , Yan Luo , Mengyu Wang

Prescriptive process monitoring is a family of techniques to optimize the performance of a business process by triggering interventions at runtime. Existing prescriptive process monitoring techniques assume that the number of interventions…

Machine Learning · Computer Science 2021-10-12 Mahmoud Shoush , Marlon Dumas

Sequential experimental design to discover interventions that achieve a desired outcome is a key problem in various domains including science, engineering and public policy. When the space of possible interventions is large, making an…

Machine Learning · Computer Science 2023-08-17 Jiaqi Zhang , Louis Cammarata , Chandler Squires , Themistoklis P. Sapsis , Caroline Uhler

Clinical trials involving multiple treatments utilize randomization of the treatment assignments to enable the evaluation of treatment efficacies in an unbiased manner. Such evaluation is performed in post hoc studies that usually use…

Artificial Intelligence · Computer Science 2018-09-10 Yogatheesan Varatharajah , Brent Berry , Sanmi Koyejo , Ravishankar Iyer

Clinicians prescribe antibiotics by looking at the patient's health record with an experienced eye. However, the therapy might be rendered futile if the patient has drug resistance. Determining drug resistance requires time-consuming…

Artificial Intelligence · Computer Science 2023-03-09 Honglin Shu , Pei Gao , Lingwei Zhu , Zheng Chen

A crucial difference between single- and multi-document summarization is how salient content manifests itself in the document(s). While such content may appear at the beginning of a single document, essential information is frequently…

Computation and Language · Computer Science 2021-10-18 Logan Lebanoff , Bingqing Wang , Zhe Feng , Fei Liu

Due to increased access to clinical trial outcomes and analysis, researchers and scientists are able to iterate or improve upon relevant approaches more effectively. However, the metrics and related results of clinical trials typically do…

Computation and Language · Computer Science 2021-01-12 Shwetha Bharadwaj , Melanie Laffin

In recent years, the trend of deploying digital systems in numerous industries has hiked. The health sector has observed an extensive adoption of digital systems and services that generate significant medical records. Electronic health…

Computation and Language · Computer Science 2022-03-01 Neel Kanwal , Giuseppe Rizzo