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Nuclear spin imaging at the atomic level is essential for the understanding of fundamental biological phenomena and for applications such as drug discovery. The advent of novel nano-scale sensors has given hope of achieving the…

Quantum Physics · Physics 2015-11-25 Ashok Ajoy , Ulf Bissbort , Mikhail D. Lukin , Ronald L. Walsworth , Paola Cappellaro

Single-molecule nuclear magnetic resonance (NMR) is a crown-jewel challenge in the field of magnetic resonance spectroscopy and has important applications in chemical analysis and in quantum computing. Recently, it becomes possible to…

Mesoscale and Nanoscale Physics · Physics 2015-06-17 Fazhan Shi , Xi Kong , Pengfei Wang , Fei Kong , Nan Zhao , Ren-Bao Liu , Jiangfeng Du

Optically active spin defects in solids offer promising platforms to investigate nuclear spin clusters with high sensitivity and atomic-site resolution. To leverage near-surface defects for molecular structure analysis in chemical and…

Nuclear Magnetic Resonance (NMR) spectrometry uses electro-frequency pulses to probe the resonance of a compound's nucleus, which is then analyzed to determine its structure. The acquisition time of high-resolution NMR spectra remains a…

Nuclear magnetic resonance (NMR) spectroscopy is a powerful technique to study local magnetism in a variety of materials. However, the inherently low sensitivity of conventional inductively detected solid state NMR typically requires a…

Mesoscale and Nanoscale Physics · Physics 2025-12-16 Louis Beaudoin , Aimé Verrier , Youcef A. Bioud , Mathieu Massicotte , Bertrand Reulet , Jeffrey A. Quilliam

In this review, we describe the potentialities offered by the nuclear magnetic resonance (NMR) technique to explore at a microscopic level new quantum states of condensed matter induced by high magnetic fields. We focus on experiments…

Strongly Correlated Electrons · Physics 2017-11-30 Claude Berthier , Mladen Horvatić , Marc-Henri Julien , Hadrien Mayaffre , Steffen Krämer

Nuclear magnetic resonance (NMR) at the single-molecule level with atomic resolution holds transformative potential for structural biology and surface chemistry. Near-surface solid-state spin sensors with optical readout ability offer a…

Quantum Physics · Physics 2025-12-12 Yu Chen , Qi Zhang , Yuanhong Teng , Chihang Luo , Zhijie Li , Jinpeng Liu , Ya Wang , Fazhan Shi , Jiangfeng Du

Nanoscale magnetic resonance imaging (NanoMRI) is an active area of applied research with potential use in structural biology and quantum engineering. The success of this technological vision hinges on improving the instrument's sensitivity…

Magnetic resonance spectroscopy is universally regarded as one of the most important tools in chemical and bio-medical research. However, sensitivity limitations typically restrict imaging resolution to length scales greater than 10 \mu m.…

Nuclear magnetic resonance (NMR) spectroscopy has approached the limit of single molecule sensitivity, however the spectral resolution is currently insufficient to obtain detailed information on chemical structure and molecular…

Quantum Physics · Physics 2015-08-19 Xi Kong , Alexander Stark , Jiangfeng Du , Liam P. McGuinness , Fedor Jelezko

The nitrogen-vacancy (NV) center has enabled widespread study of nanoscale nuclear magnetic resonance (NMR) spectroscopy at low magnetic fields. NMR spectroscopy at high magnetic fields significantly improves the technique's spectral…

Mesoscale and Nanoscale Physics · Physics 2021-09-15 Benjamin Fortman , Laura Mugica-Sanchez , Noah Tischler , Cooper Selco , Yuxiao Hang , Karoly Holczer , Susumu Takahashi

Quantum sensors based on nitrogen-vacancy centers in diamond have emerged as a promising detection modality for nuclear magnetic resonance (NMR) spectroscopy owing to their micron-scale detection volume and non-inductive based detection. A…

Nuclear magnetic resonance (NMR) schemes can be applied to micron-, and nanometer-sized samples by the aid of quantum sensors such as nitrogen-vacancy (NV) color centers in diamond. These minute devices allow for magnetometry of nuclear…

Quantum Physics · Physics 2021-07-19 C. Munuera-Javaloy , R. Puebla , J. Casanova

Nitrogen vacancy (NV) centers in diamond have been used as ultrasensitive magnetometers to perform nuclear magnetic resonance (NMR) spectroscopy of statistically polarized samples at 1 - 100 nm length scales. However, the spectral linewidth…

We experimentally demonstrate precision addressing of single quantum emitters by combined optical microscopy and spin resonance techniques. To this end we utilize nitrogen-vacancy (NV) color centers in diamond confined within a few ten…

Quantum Physics · Physics 2017-10-20 Matthias Pfender , Nabeel Aslam , Gerald Waldherr , Jörg Wrachtrup

Quantum sensors have attracted broad interest in the quest towards sub-micronscale NMR spectroscopy. Such sensors predominantly operate at low magnetic fields. Instead, however, for high resolution spectroscopy, the high-field regime is…

The nuclear spins in nanostructured semiconductors play a central role in quantum applications. The nuclear spins represent a useful resource for generating local magnetic fields but nuclear spin noise represents a major source of dephasing…

We review instrumentation for nuclear magnetic resonance (NMR) in zero and ultra-low magnetic field (ZULF, below 0.1 $\mu$T) where detection is based on a low-cost, non-cryogenic, spin-exchange relaxation free (SERF) $^{87}$Rb atomic…

Distance measurements via the dipolar interaction are fundamental to the application of nuclear magnetic resonance (NMR) to molecular structure determination, but they only provide information on the absolute distance $r$ and polar angle…

Quantum Physics · Physics 2018-10-30 J. Zopes , K. Herb , K. S. Cujia , C. L. Degen

The ultimate precision limit in estimating the Larmor frequency of $N$ unentangled rotating spins is well established, and is highly important for magnetometers, gyroscopes and many other sensors. However this limit assumes perfect, single…

Quantum Physics · Physics 2020-10-06 Daniel Cohen , Tuvia Gefen , Laura Ortiz , Alex Retzker