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Motivated by chemical reaction rules, we introduce a rule-based epidemiological framework for the systematic mathematical modelling of future pandemics. Here we stress that we do not have a specific model in mind, but a whole collection of…

Populations and Evolution · Quantitative Biology 2024-05-24 David Alonso , Steffen Bauer , Markus Kirkilionis , Lisa Maria Kreusser , Luca Sbano

Due to the increased complexity of software development projects more and more systems are described by models. The sheer size makes it impractical to describe these systems by a single model. Instead many models are developed that provide…

Software Engineering · Computer Science 2014-09-24 Christoph Herrmann , Holger Krahn , Bernhard Rumpe , Martin Schindler , Steven Völkel

During the ongoing COVID-19 pandemic, mathematical models of epidemic spreading have emerged as powerful tools to produce valuable predictions of the evolution of the pandemic, helping public health authorities decide which intervention…

Dynamical Systems · Mathematics 2021-11-18 Lorenzo Zino , Ming Cao

World models have emerged as a unifying paradigm for learning latent dynamics, simulating counterfactual futures, and supporting planning under uncertainty. In this paper, we argue that computational epidemiology is a natural and…

Machine Learning · Computer Science 2026-04-14 Zeeshan Memon , Yiqi Su , Christo Kurisummoottil Thomas , Walid Saad , Liang Zhao , Naren Ramakrishnan

Capturing the structured mixing within a population is key to the reliable projection of infectious disease dynamics and hence informed control. Both heterogeneity in the number of contacts and age-structured mixing have been repeatedly…

Social and Information Networks · Computer Science 2026-03-17 Luke Murray Kearney , Emma L Davis , Matt J Keeling

The adoption of containment measures to reduce the amplitude of the epidemic peak is a key aspect in tackling the rapid spread of an epidemic. Classical compartmental models must be modified and studied to correctly describe the effects of…

Populations and Evolution · Quantitative Biology 2021-05-18 G. Albi , L. Pareschi , M. Zanella

The COVID-19 pandemic has brought forth the importance of epidemic forecasting for decision makers in multiple domains, ranging from public health to the economy as a whole. While forecasting epidemic progression is frequently…

Machine Learning · Computer Science 2022-07-21 Alexander Rodríguez , Harshavardhan Kamarthi , Pulak Agarwal , Javen Ho , Mira Patel , Suchet Sapre , B. Aditya Prakash

Compartmental epidemic models have been widely used for predicting the course of epidemics, from estimating the basic reproduction number to guiding intervention policies. Studies commonly acknowledge these models' assumptions but less…

Populations and Evolution · Quantitative Biology 2022-11-23 Alexander F. Siegenfeld , Pratyush K. Kollepara , Yaneer Bar-Yam

The epidemiology has recently witnessed great advances based on computational models. Its scope and impact are getting wider thanks to the new data sources feeding analytical frameworks and models. Besides traditional variables considered…

Computers and Society · Computer Science 2023-11-13 David Pastor-Escuredo

Autonomous systems require the management of several model views to assure properties such as safety and security among others. A crucial issue in autonomous systems design assurance is the notion of emergent behavior; we cannot use their…

Logic in Computer Science · Computer Science 2022-03-31 Georgios Bakirtzis , Ufuk Topcu

Many Artificial Intelligence systems depend on the agent's updating its beliefs about the world on the basis of experience. Experiments constitute one type of experience, so scientific methodology offers a natural environment for examining…

Artificial Intelligence · Computer Science 2013-04-08 Harold P. Lehmann

Epidemiological models are an important tool in coping with epidemics, as they offer a forecast, even if often simplistic, of the behavior of the disease in the population. This allows responsible health agencies to organize themselves and…

Populations and Evolution · Quantitative Biology 2023-08-03 Eliza Maria Ferreira , Ricardo Edem Ferreira , Chiara Mocenni

The abrupt outbreak and transmission of biological diseases has always been a long-time concern of humankind. For long, mathematical modeling has served as a simple and yet efficient tool to investigate, predict, and control spread of…

Populations and Evolution · Quantitative Biology 2020-04-10 Aresh Dadlani , Richard O. Afolabi , Hyoyoung Jung , Khosrow Sohraby , Kiseon Kim

Mathematical models are increasingly used in both academia and the pharmaceutical industry to understand how phenotypes emerge from systems of molecular interactions. However, their current construction as monolithic sets of equations…

Molecular Networks · Quantitative Biology 2007-10-19 Aneil Mallavarapu , Matthew Thomson , Benjamin Ullian , Jeremy Gunawardena

In the present paper, our goal is to establish a framework for the mathematical modelling and the analysis of the spread of an epidemic in a large population commuting regularly, typically along a time-periodic pattern, as is roughly…

Populations and Evolution · Quantitative Biology 2024-08-29 Pierre-Alexandre Bliman , Boureima Sangaré , Assane Savadogo

We develop a general modelling framework for compartmental epidemiological systems structured by continuous variables which are linked to the levels of expression of compartment-specific traits. We start by formulating an individual-based…

Populations and Evolution · Quantitative Biology 2025-08-14 Emanuele Bernardi , Tommaso Lorenzi , Mattia Sensi , Andrea Tosin

Deterministic compartmental models have been used extensively in modeling epidemic propagation. These models are required to fit available data and numerical procedures are often implemented to this end. But not every model architecture is…

Populations and Evolution · Quantitative Biology 2021-11-23 Gabriel Turinici

Epidemic modeling is essential for public health planning, yet traditional approaches rely on fixed model classes that require manual redesign as pathogens, policies, and scenario assumptions evolve. We introduce EPIAGENT, an agentic…

Augmenting classical epidemiological models with information from the social sciences helps unveil the interplay between contagion dynamics and social responses. However, multidisciplinary integration of social analysis and epidemiological…

Physics and Society · Physics 2025-07-29 Daniele Proverbio , Riccardo Tessarin , Giulia Giordano

The emergence of large language models offers new possibilities for structured exploration of scientific knowledge. Rather than viewing scientific discovery as isolated ideas or content, we propose a structured approach that emphasizes the…

Artificial Intelligence · Computer Science 2025-04-15 Junlan Chen , Kexin Zhang , Daifeng Li , Yangyang Feng , Yuxuan Zhang , Bowen Deng
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