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Recent efforts in Machine Learning (ML) interpretability have focused on creating methods for explaining black-box ML models. However, these methods rely on the assumption that simple approximations, such as linear models or decision-trees,…

Machine Learning · Computer Science 2019-06-13 Owen Lahav , Nicholas Mastronarde , Mihaela van der Schaar

Black-box deep learning approaches have showcased significant potential in the realm of medical image analysis. However, the stringent trustworthiness requirements intrinsic to the medical field have catalyzed research into the utilization…

Computer Vision and Pattern Recognition · Computer Science 2024-01-17 Yequan Bie , Luyang Luo , Hao Chen

Natural disasters ravage the world's cities, valleys, and shores on a regular basis. Deploying precise and efficient computational mechanisms for assessing infrastructure damage is essential to channel resources and minimize the loss of…

Computer Vision and Pattern Recognition · Computer Science 2022-01-28 Thomas Y. Chen

Although deep learning models are powerful among various applications, most deep learning models are still a black box, lacking verifiability and interpretability, which means the decision-making process that human beings cannot understand.…

Computer Vision and Pattern Recognition · Computer Science 2021-09-29 Qianmengke Zhao , Ye Wang , Qun Liu

As an intuitive description of complex physical, social, or brain systems, complex networks have fascinated scientists for decades. Recently, to abstract a network's structural and dynamical attributes for utilization, network…

Social and Information Networks · Computer Science 2022-10-21 Yue Deng

Convolutional neural networks (CNNs) are widely used for high-stakes applications like medicine, often surpassing human performance. However, most explanation methods rely on post-hoc attribution, approximating the decision-making process…

Machine Learning · Computer Science 2026-02-23 Kerol Djoumessi , Philipp Berens

In recent years, the scientific community has focused on the development of CAD tools that could improve bone fractures' classification, mostly based on Convolutional Neural Network (CNN). However, the discerning accuracy of fractures'…

Artificial Intelligence · Computer Science 2021-10-27 Leonardo Tanzi , Andrea Audisio , Giansalvo Cirrincione , Alessandro Aprato , Enrico Vezzetti

Digital mammography is essential to breast cancer detection, and deep learning offers promising tools for faster and more accurate mammogram analysis. In radiology and other high-stakes environments, uninterpretable ("black box") deep…

Computer Vision and Pattern Recognition · Computer Science 2024-06-11 Julia Yang , Alina Jade Barnett , Jon Donnelly , Satvik Kishore , Jerry Fang , Fides Regina Schwartz , Chaofan Chen , Joseph Y. Lo , Cynthia Rudin

In intensive care units (ICUs), critically ill patients are monitored with electroencephalograms (EEGs) to prevent serious brain injury. The number of patients who can be monitored is constrained by the availability of trained physicians to…

Explanations for deep neural network predictions in terms of domain-related concepts can be valuable in medical applications, where justifications are important for confidence in the decision-making. In this work, we propose a methodology…

Machine Learning · Computer Science 2019-04-10 Mara Graziani , Vincent Andrearczyk , Henning Müller

Deep reinforcement learning (DRL), through learning policies or values represented by neural networks, has successfully addressed many complex control problems. However, the neural networks introduced by DRL lack interpretability and…

Machine Learning · Computer Science 2025-02-04 Zeyu Jiang , Hai Huang , Xingquan Zuo

The use of deep neural models for diagnosis prediction from clinical text has shown promising results. However, in clinical practice such models must not only be accurate, but provide doctors with interpretable and helpful results. We…

Neuron identification is a popular tool in mechanistic interpretability, aiming to uncover the human-interpretable concepts represented by individual neurons in deep networks. While algorithms such as Network Dissection and CLIP-Dissect…

Artificial Intelligence · Computer Science 2025-12-23 Ge Yan , Tuomas Oikarinen , Tsui-Wei , Weng

We describe a method for verifying the output of a deep neural network for medical image segmentation that is robust to several classes of random as well as worst-case perturbations i.e. adversarial attacks. This method is based on a…

Computer Vision and Pattern Recognition · Computer Science 2023-12-21 Fahim Ahmed Zaman , Xiaodong Wu , Weiyu Xu , Milan Sonka , Raghuraman Mudumbai

Deep learning methods, in particular convolutional neural networks, have emerged as a powerful tool in medical image computing tasks. While these complex models provide excellent performance, their black-box nature may hinder real-world…

Image and Video Processing · Electrical Eng. & Systems 2022-10-18 Yuzhe Lu , Adam Perer

Despite the remarkable performance, Deep Neural Networks (DNNs) behave as black-boxes hindering user trust in Artificial Intelligence (AI) systems. Research on opening black-box DNN can be broadly categorized into post-hoc methods and…

Machine Learning · Computer Science 2021-06-25 Sandareka Wickramanayake , Wynne Hsu , Mong Li Lee

Deep learning methods for classifying medical images have demonstrated impressive accuracy in a wide range of tasks but often these models are hard to interpret, limiting their applicability in clinical practice. In this work we introduce a…

Image and Video Processing · Electrical Eng. & Systems 2019-08-13 James R. Clough , Ilkay Oksuz , Esther Puyol-Anton , Bram Ruijsink , Andrew P. King , Julia A. Schnabel

Large datasets often contain multiple distinct feature sets, or views, that offer complementary information that can be exploited by multi-view learning methods to improve results. We investigate anatomical multi-view data, where each brain…

Quantitative Methods · Quantitative Biology 2024-01-17 Yuxiang Wei , Yuqian Chen , Tengfei Xue , Leo Zekelman , Nikos Makris , Yogesh Rathi , Weidong Cai , Fan Zhang , Lauren J. O' Donnell

Explaining recommendations enables users to understand whether recommended items are relevant to their needs and has been shown to increase their trust in the system. More generally, if designing explainable machine learning models is key…

Machine Learning · Computer Science 2020-08-27 Darius Afchar , Romain Hennequin

Interpretability of deep learning is widely used to evaluate the reliability of medical imaging models and reduce the risks of inaccurate patient recommendations. For models exceeding human performance, e.g. predicting RNA structure from…

Quantitative Methods · Quantitative Biology 2022-08-31 Mara Graziani , Niccolò Marini , Nicolas Deutschmann , Nikita Janakarajan , Henning Müller , María Rodríguez Martínez