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Solving the software dependency issue under the HPC environment has always been a difficult task for both computing system administrators and application scientists. This work would like to tackle the issue by introducing the modern…

Distributed, Parallel, and Cluster Computing · Computer Science 2015-09-29 Hsi-En Yu , Weicheng Huang

Virtualization is generally adopted in server and desktop environments to provide for fault tolerance, resource management, and energy efficiency. Virtualization enables parallel execution of multiple operating systems (OSs) while sharing…

Operating Systems · Computer Science 2016-05-05 Junaid Shuja , Abdullah Gani , Sajjad A. Madani

The biomedical literature contains a vast collection of omics studies, yet most published data remain functionally inaccessible for computational reuse. When raw data are deposited in public repositories, essential information for…

Genomics · Quantitative Biology 2026-03-16 Alexandre Hutton , Jesse G. Meyer

This paper proposes a novel approach to scaling distributed collaboration in mixed reality by virtualizing collaborative tasks as independent, installable environments. By mapping group activities into dedicated virtual spaces that adapt to…

Human-Computer Interaction · Computer Science 2025-04-07 Euijun Jung , Youngki Lee

The computational demands for scientific applications are continuously increasing. The emergence of cloud computing has enabled on-demand resource allocation. However, relying solely on infrastructure as a service does not achieve the…

Distributed, Parallel, and Cluster Computing · Computer Science 2019-11-13 Marco Capuccini , Anders Larsson , Matteo Carone , Jon Ander Novella , Noureddin Sadawi , Jianliang Gao , Salman Toor , Ola Spjuth

Developing large-scale foundational datasets is a critical milestone in advancing artificial intelligence (AI)-driven scientific innovation. However, unlike AI-mature fields such as natural language processing, materials science,…

Chemical Physics · Physics 2025-11-18 Ryo Yoshida , Yoshihiro Hayashi , Hidemine Furuya , Ryohei Hosoya , Kazuyoshi Kaneko , Hiroki Sugisawa , Yu Kaneko , Aiko Takahashi , Yoh Noguchi , Shun Nanjo , Keiko Shinoda , Tomu Hamakawa , Mitsuru Ohno , Takuya Kitamura , Misaki Yonekawa , Stephen Wu , Masato Ohnishi , Chang Liu , Teruki Tsurimoto , Arifin , Araki Wakiuchi , Kohei Noda , Junko Morikawa , Teruaki Hayakawa , Junichiro Shiomi , Masanobu Naito , Kazuya Shiratori , Tomoki Nagai , Norio Tomotsu , Hiroto Inoue , Ryuichi Sakashita , Masashi Ishii , Isao Kuwajima , Kenji Furuichi , Norihiko Hiroi , Yuki Takemoto , Takahiro Ohkuma , Keita Yamamoto , Naoya Kowatari , Masato Suzuki , Naoya Matsumoto , Seiryu Umetani , Hisaki Ikebata , Yasuyuki Shudo , Mayu Nagao , Shinya Kamada , Kazunori Kamio , Taichi Shomura , Kensaku Nakamura , Yudai Iwamizu , Atsutoshi Abe , Koki Yoshitomi , Yuki Horie , Katsuhiko Koike , Koichi Iwakabe , Shinya Gima , Kota Usui , Gikyo Usuki , Takuro Tsutsumi , Keitaro Matsuoka , Kazuki Sada , Masahiro Kitabata , Takuma Kikutsuji , Akitaka Kamauchi , Yusuke Iijima , Tsubasa Suzuki , Takenori Goda , Yuki Takabayashi , Kazuko Imai , Yuji Mochizuki , Hideo Doi , Koji Okuwaki , Hiroya Nitta , Taku Ozawa , Hitoshi Kamijima , Toshiaki Shintani , Takuma Mitamura , Massimiliano Zamengo , Yuitsu Sugami , Seiji Akiyama , Yoshinari Murakami , Atsushi Betto , Naoya Matsuo , Satoru Kagao , Tetsuya Kobayashi , Norie Matsubara , Shosei Kubo , Yuki Ishiyama , Yuri Ichioka , Mamoru Usami , Satoru Yoshizaki , Seigo Mizutani , Yosuke Hanawa , Shogo Kunieda , Mitsuru Yambe , Takeru Nakamura , Hiromori Murashima , Kenji Takahashi , Naoki Wada , Masahiro Kawano , Yosuke Harada , Takehiro Fujita , Erina Fujita , Ryoji Himeno , Hiori Kino , Kenji Fukumizu

The development of critical systems is becoming more and more complex. The overall tendency is that development costs raise. In order to cut cost of development, companies are forced to build systems from proven components and larger new…

Software Engineering · Computer Science 2016-05-25 Aleksander Lodwich , Jose María Alvarez-Rodríguez

As software systems increase in complexity, conventional monitoring methods struggle to provide a comprehensive overview or identify performance issues, often missing unexpected problems. Observability, however, offers a holistic approach,…

Distributed, Parallel, and Cluster Computing · Computer Science 2024-08-29 Bartosz Balis , Konrad Czerepak , Albert Kuzma , Jan Meizner , Lukasz Wronski

Since the advent of next-generation sequencing in the early 2000s, the volume of bioinformatics software tools and databases has exploded and continues to grow rapidly. Documenting this evolution on a global and time-dependent scale is a…

Software containers are widely adopted for developing and deploying software applications. Despite their popularity, major security concerns arise during container development and deployment. Software Engineering (SE) research literature…

Software Engineering · Computer Science 2025-12-16 Maha Sroor , Teerath Das , Rahul Mohanani , Tommi Mikkonen

Computational methods are the most effective tools we have besides scientific experiments to explore the properties of complex biological systems. Progress is slowing because digital silicon computers have reached their limits in terms of…

Quantum Physics · Physics 2020-04-03 Viv Kendon

The continuing advances of omic technologies mean that it is now more tangible to measure the numerous features collectively reflecting the molecular properties of a sample. When multiple omic methods are used, statistical and computational…

Genomics · Quantitative Biology 2023-08-14 Tim Downing , Nicos Angelopoulos

Virtualization is a key building block of next-generation mobile networks. It can be implemented through two main approaches: traditional virtual machines and lighter-weight containers. Our objective in this paper is to compare these…

Networking and Internet Architecture · Computer Science 2018-09-12 Senay Semu Tadesse , Carla Fabiana Chiasserini , Francesco Malandrino

Computational models and simulations are not just appealing because of their intrinsic characteristics across spatiotemporal scales, scalability, and predictive power, but also because the set of problems in cancer biomedicine that can be…

Tissues and Organs · Quantitative Biology 2023-11-01 Nicolò Cogno , Cristian Axenie , Roman Bauer , Vasileios Vavourakis

With the growing demand for openness, scalability, and granularity, mobile network function virtualization (NFV) has emerged as a key enabler for most mobile network operators. NFV decouples network functions from hardware devices. This…

Networking and Internet Architecture · Computer Science 2022-04-04 Wissal Attaoui , Essaid Sabir , Halima Elbiaze , Mohsen Guizani

In this paper, we discuss the need for an integrated software stack that unites artificial intelligence (AI) and modeling and simulation (ModSim) tools to advance scientific discovery. The authors advocate for a unified AI/ModSim software…

Software Engineering · Computer Science 2024-11-15 Michael A. Heroux , Sameer Shende , Lois Curfman McInnes , Todd Gamblin , James M. Willenbring

Probabilistic models inform an increasingly broad range of business and policy decisions ultimately made by people. Recent algorithmic, computational, and software framework development progress facilitate the proliferation of Bayesian…

Human-Computer Interaction · Computer Science 2022-01-12 Sebastian Stein , John H. Williamson

Open source software is a rapidly evolving center for distributed work, and understanding the characteristics of this work across its different contexts is vital for informing policy, economics, and the design of enabling software. The…

Software Engineering · Computer Science 2025-04-24 Wenyi Lu , Enock Kasaadah , S M Rakib Ul Karim , Matt Germonprez , Sean Goggins

The complexity of biological systems, governed by molecular interactions across hierarchical scales, presents a challenge for computational modeling. While advances in multiomic profiling have enabled precise measurements of biological…

Quantum Physics · Physics 2025-06-18 Michael Kubal , Sonika Johri

Benchmarking, which involves collecting reference datasets and demonstrating method performances, is a requirement for the development of new computational tools, but also becomes a domain of its own to achieve neutral comparisons of…

Other Quantitative Biology · Quantitative Biology 2025-07-24 Izaskun Mallona , Charlotte Soneson , Ben Carrillo , Almut Luetge , Daniel Incicau , Reto Gerber , Anthony Sonrel , Mark D. Robinson