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The potential benefits of applying machine learning methods to -omics data are becoming increasingly apparent, especially in clinical settings. However, the unique characteristics of these data are not always well suited to machine learning…

Customization is a general trend in software engineering, demanding systems that support variable stakeholder requirements. Two opposing strategies are commonly used to create variants: software clone & own and software configuration with…

Software Engineering · Computer Science 2021-03-03 Wardah Mahmood , Daniel Strüber , Thorsten Berger , Ralf Lämmel , Mukelabai Mukelabai

Computational micromagnetics requires numerical solution of partial differential equations to resolve complex interactions in magnetic nanomaterials. The Virtual Micromagnetics project described here provides virtual machine simulation…

Other Computer Science · Computer Science 2016-11-28 Mark Vousden , Marc-Antonio Bisotti , Maximilian Albert , Hans Fangohr

Virtualization technologies allow multiple tenants to share physical resources with a degree of security and isolation that cannot be guaranteed by mere containerization. Further, virtualization allows protected transparent introspection of…

Cryptography and Security · Computer Science 2018-08-03 Roberto Di Pietro , Flavio Lombardi

Cloud computing has become the backbone of the computing industry and offers subscription-based on-demand services. Through virtualization, which produces a virtual instance of a computer system running in an abstracted hardware layer, it…

Distributed, Parallel, and Cluster Computing · Computer Science 2022-07-19 Sakshi Chhabra , Ashutosh Kumar Singh

Be it for a malicious or legitimate purpose, packing, a transformation that consists in applying various operations like compression or encryption to a binary file, i.e. for making reverse engineering harder or obfuscating code, is widely…

Cryptography and Security · Computer Science 2023-02-21 Alexandre D'Hondt , Charles-Henry Bertrand Van Ouytsel , Axel Legay

The Rocker Project provides widely used Docker images for R across different application scenarios. This article surveys downstream projects that build upon the Rocker Project images and presents the current state of R packages for managing…

Containers are standalone, self-contained units that package software and its dependencies together. They offer lightweight performance isolation, fast and flexible deployment, and fine-grained resource sharing. They have gained popularity…

Distributed, Parallel, and Cluster Computing · Computer Science 2018-12-04 Maria A. Rodriguez , Rajkumar Buyya

The multidisciplinarity of robotics creates a need for robust integration methodologies that can facilitate the adoption of state-of-the-art research components in an industrial application. Unfortunately, there are no clear, community…

Rapid advances in quantum computing technology lead to an increasing need for software simulators that enable both algorithm design and the validation of results obtained from quantum hardware. This includes calculations that aim at probing…

Quantum Physics · Physics 2025-01-09 Amit Jamadagni , Andreas M. Läuchli , Cornelius Hempel

The challenge of translating vast, multimodal biological data into predictive and mechanistic understanding of cellular function is a central theme in modern biology. Virtual cells, or digital cellular twins, have emerged as a critical…

Quantitative Methods · Quantitative Biology 2025-09-24 Saurabh Bhardwaj , Gaurav Kumar , Haochen Yang , Shaurya Bhardwaj , Qun Wang , Minjie Shen , Yizhi Wang , Cristabelle Madona De Souza

In the last years, Distributed Visualization over Personal Computer (PC) clusters has become important for research and industrial communities. They have made large-scale visualizations practical and more accessible. In this work we survey…

Graphics · Computer Science 2015-07-07 Jose Rodrigues , Andre Balan , Luciana Zaina , Agma Traina

Containers are an emerging technology that hold promise for improving productivity and code portability in scientific computing. We examine Linux container technology for the distribution of a non-trivial scientific computing software stack…

Distributed, Parallel, and Cluster Computing · Computer Science 2017-06-19 Jack S. Hale , Lizao Li , Chris N. Richardson , Garth N. Wells

Container technique is gaining increasing attention in recent years and has become an alternative to traditional virtual machines. Some of the primary motivations for the enterprise to adopt the container technology include its convenience…

Distributed, Parallel, and Cluster Computing · Computer Science 2018-07-06 Qi Zhang , Ling Liu , Calton Pu , Qiwei Dou , Liren Wu , Wei Zhou

At present, the mostly used and developed mechanism is hardware virtualization which provides a common platform to run multiple operating systems and applications in independent partitions. More precisely, it is all about resource…

Hardware Architecture · Computer Science 2009-09-02 Kamanashis Biswas , Md. Ashraful Islam

Software development industries are increasingly adopting containers to enhance the scalability and flexibility of software applications. Security in containerized projects is a critical challenge that can lead to data breaches and…

Software Engineering · Computer Science 2025-04-11 Maha Sroor , Rahul Mohanani , Ricardo Colomo-Palacios , Sandun Dasanayake , Tommi Mikkonen

Development of scientific and engineering software is usually different and could be more challenging than the development of conventional enterprise software. The authors were involved in a technology-transfer project between academia and…

Software Engineering · Computer Science 2020-03-03 Vahid Garousi , Ehsan Abbasi , Bedir Tekinerdogan

At the frontier of most areas in science, computer simulations play a central role. The traditional division of natural science into experimental and theoretical investigations is now completely outdated. Instead, theory, simulation, and…

Astrophysics · Physics 2008-11-26 Piet Hut

Recent developments in spatial omics technologies have enabled the generation of high dimensional molecular data, such as transcriptomes, proteomes, and epigenomes, within their spatial tissue context, either through coprofiling on the same…

Quantitative Methods · Quantitative Biology 2026-01-21 Esra Busra Isik , Yusuf Hakan Usta , Haozhe Liu , Maryam Riazi , William Roach , Hongpeng Zhou , Magnus Rattray , Sokratia Georgaka

Open software ecosystems are beneficial for customers; they benefit from 3rd party services and applications, e.g. analysis of data using apps, developed and deployed by other companies or open-source communities. One significant advantage…

Cryptography and Security · Computer Science 2024-05-21 Christian Binkowski , Stefan Appel , Andreas Aßmuth