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Pulmonary arterial hypertension (PAH) is a progressive cardiopulmonary disease that leads to increased pulmonary pressures, vascular remodeling, and eventual right ventricular (RV) failure. Pediatric PAH remains understudied due to limited…

Cardiotocography (CTG) is a key element when it comes to monitoring fetal well-being. Obstetricians use it to observe the fetal heart rate (FHR) and the uterine contraction (UC). The goal is to determine how the fetus reacts to the…

Signal Processing · Electrical Eng. & Systems 2022-10-03 Julien Bertieaux , Mohammadhadi Shateri , Fabrice Labeau , Thierry Dutoit

The hierarchical Dirichlet process (HDP) has become an important Bayesian nonparametric model for grouped data, such as document collections. The HDP is used to construct a flexible mixed-membership model where the number of components is…

Machine Learning · Statistics 2012-01-10 Chong Wang , David M. Blei

Accurately predicting hospital readmission risks using electronic health records (EHRs) is critical for effective patient management and healthcare resource allocation. Patient populations in health systems are highly heterogeneous across…

The majority of Americans fail to achieve recommended levels of physical activity, which leads to numerous preventable health problems such as diabetes, hypertension, and heart diseases. This has generated substantial interest in monitoring…

There are many issues that can cause problems when attempting to infer model parameters from data. Data and models are both imperfect, and as such there are multiple scenarios in which standard methods of inference will lead to misleading…

Computation · Statistics 2024-05-01 Simon L. Cotter

We present a method for identification of models with good predictive performances in the family of Bayesian log-linear mixed models with Dirichlet process random effects. Such a problem arises in many different applications; here we…

Methodology · Statistics 2018-01-17 Cinzia Carota , Maurizio Filippone , Silvia Polettini

Hypertension is one of the most common age-related chronic diseases and by predisposing individuals for heart failure, stroke and kidney disease, it is a major source of morbidity and mortality. Its etiology remains enigmatic despite…

Tissues and Organs · Quantitative Biology 2015-06-15 Klas H. Pettersen , Scott M. Bugenhagen , Javaid Nauman , Daniel A. Beard , Stig W. Omholt

One of the most significant barriers to medication treatment is patients' non-adherence to a prescribed medication regimen. The extent of the impact of poor adherence on resulting health measures is often unknown, and typical analyses…

Applications · Statistics 2018-12-04 Luis F. Campos , Mark E. Glickman , Kristen B. Hunter

Observational causal inference is useful for decision making in medicine when randomized clinical trials (RCT) are infeasible or non generalizable. However, traditional approaches fail to deliver unconfounded causal conclusions in practice.…

Recent studies show the existing clinical tests to detect Cardio/cerebrovascular diseases (CVD) are ineffectual as they do not consider different stages of platelet activation or the molecular dynamics involved in platelet interactions.…

This paper considers the practically important case of nonparametrically estimating heterogeneous average treatment effects that vary with a limited number of discrete and continuous covariates in a selection-on-observables framework where…

Econometrics · Economics 2019-08-26 Michael Zimmert , Michael Lechner

Aggressive behavior in autistic inpatient youth often arises in temporally clustered bursts complicating efforts to distinguish external triggers from internal escalation. The sample population branching factor-the expected number of new…

Statistical agencies and other institutions collect data under the promise to protect the confidentiality of respondents. When releasing microdata samples, the risk that records can be identified must be assessed. To this aim, a widely…

Applications · Statistics 2015-06-03 Cinzia Carota , Maurizio Filippone , Roberto Leombruni , Silvia Polettini

Prenatal psychological stress affects 15-25% of pregnancies and increases risks of preterm birth, low birth weight, and adverse neurodevelopmental outcomes. Current screening relies on subjective questionnaires (PSS-10), limiting continuous…

Quantitative Methods · Quantitative Biology 2026-04-28 Martin G. Frasch , Marlene J. E. Mayer , Clara Becker , Peter Zimmermann , Camilla Zelgert , Marta C. Antonelli , Silvia M. Lobmaier

A database of fetal heart rate (FHR) time series measured from 7221 patients during labor is analyzed with the aim of learning the types of features of these recordings that are informative of low cord pH. Our 'highly comparative' analysis…

Machine Learning · Computer Science 2014-12-04 B. D. Fulcher , A. E. Georgieva , C. W. G. Redman , Nick S. Jones

Hierarchical model fitting has become commonplace for case-control studies of cognition and behaviour in mental health. However, these techniques require us to formalise assumptions about the data-generating process at the group level,…

Computers and Society · Computer Science 2020-11-04 Vincent Valton , Toby Wise , Oliver J. Robinson

Efficient management of low blood pressure (BP) in preterm neonates remains challenging with a considerable variability in clinical practice. The ability to assess preterm wellbeing during episodes of low BP will help to decide when and…

Multi-level modeling is an important approach for analyzing complex survey data using multi-stage sampling. However, estimation of multi-level models can be challenging when we combine several datasets with distinct hierarchies with…

Methodology · Statistics 2023-09-26 Seho Park , A James OMalley

Heart disease is the major cause of non-communicable and silent death worldwide. Heart diseases or cardiovascular diseases are classified into four types: coronary heart disease, heart failure, congenital heart disease, and cardiomyopathy.…

Machine Learning · Computer Science 2023-06-22 Achyut Tiwari , Aryan Chugh , Aman Sharma
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